Lyso-PAF,a biologically inactive phospholipid,contributes to RAF1 activation

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Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway

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RASopathy mutations provide functional insight into the BRAF cysteine-rich domain and reveal the importance of autoinhibition in BRAF regulation

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Sensor histidine kinases mediate ABA and osmostress signaling in the moss Physcomitrium patens

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Regulation of GTPase function by autophosphorylation

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Captured snapshots of PARP1 in the active state reveal the mechanics of PARP1 allostery

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RIPK1 Promotes Energy Sensing by the mTORC1 Pathway

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Modulating HIV-1 envelope glycoprotein conformation to decrease the HIV-1 reservoir

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RIF1 suppresses the formation of single-stranded ultrafine anaphase bridges via protein phosphatase 1

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Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1

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Self-incompatibility requires GPI anchor remodeling by the poppy PGAP1 ortholog HLD1

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Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1

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Molecular insight into the PCNA-binding mode of FBH1

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Virus-Mediated Suppression of the Antigen Presentation Molecule MR1

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Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A

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Failure of digit tip regeneration in the absence of Lmx1b suggests Lmx1b functions disparate from dorsoventral polarity

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Extrinsic control of the early postnatal CA1 hippocampal circuits

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PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway

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Stn1-Ten1 and Taz1 independently promote replication of subtelomeric fragile sequences in fission yeast

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Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise

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