The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining

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Unique Structural Features of Mammalian NEIL2 DNA Glycosylase Prime Its Activity for Diverse DNA Substrates and Environments

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MeCP2 Represses Enhancers through Chromosome Topology-Associated DNA Methylation

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Zinc Fingers 10 and 11 of Miz-1 undergo conformational exchange to achieve specific DNA binding

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DEAD-Box Helicase 18 Counteracts PRC2 to Safeguard Ribosomal DNA in Pluripotency Regulation

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Sequence and chromatin features guide DNA double-strand break resection initiation

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Loss of Ezh2 function remodels the DNA replication initiation landscape

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Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners

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BLM has Contrary Effects on Repeat-Mediated Deletions,based on the Distance of DNA DSBs to a Repeat and Repeat Divergence

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Calcineurin dephosphorylates topoisomerase IIβ and regulates the formation of neuronal-activity-induced DNA breaks

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Methylation of histone H3 at lysine 37 by Set1 and Set2 prevents spurious DNA replication

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Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon

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Human DNA polymerase θ harbors DNA end-trimming activity critical for DNA repair

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The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition

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Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells

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Persistence of RNA transcription during DNA replication delays duplication of transcription start sites until G2/M

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Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks

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PARylation of BRCA1 limits DNA break resection through BRCA2 and EXO1

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Thermosensitive Nucleosome Editing Reveals the Role of DNA Sequence in Targeted Histone Variant Deposition

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Functional interrogation of DNA damage response variants with base editing screens

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