Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex

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MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts

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RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation

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The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism

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GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis

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Comprehensive in vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms

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Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair

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Terminal modification,sequence, length,and PIWI-protein identity determine piRNA stability

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A functional link between lariat debranching enzyme and the intron-binding complex is defective in non-photosensitive trichothiodystrophy

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iTAG-RNA Isolates Cell-Specific Transcriptional Responses to Environmental Stimuli and Identifies an RNA-Based Endocrine Axis

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Small RNAs and Hfq capture unfolded RNA target sites during transcription

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Mammalian RNA Decay Pathways Are Highly Specialized and Widely Linked to Translation

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Probing RNA Conformational Equilibria within the Functional Cellular Context

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Expansion of the global RNA virome reveals diverse clades of bacteriophages

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Stepwise sRNA targeting of structured bacterial mRNAs leads to abortive annealing

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CRISPR-free,programmable RNA pseudouridylation to suppress premature termination codons

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Computationally reconstructing cotranscriptional RNA folding from experimental data reveals rearrangement of non-native folding intermediates

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POINT technology illuminates the processing of polymerase-associated intact nascent transcripts

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High-resolution quantitative profiling of tRNA abundance and modification status in eukaryotes by mim-tRNAseq

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Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex

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