Structural Insights into the Human Pre-mRNA 3′-End Processing Machinery

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Functional analysis of a random-sequence chromosome reveals a high level and the molecular nature of transcriptional noise in yeast cells

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Integrator is a genome-wide attenuator of non-productive transcription

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Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration

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Differential Alternative Polyadenylation Landscapes Mediate Hematopoietic Stem Cell Activation and Regulate Glutamine Metabolism

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Dense Transposon Integration Reveals Essential Cleavage and Polyadenylation Factors Promote Heterochromatin Formation

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TERRA stability is regulated by RALY and polyadenylation in a telomere-specific manner

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Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing

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Regulation of alternative polyadenylation by the C2H2-zinc-finger protein Sp1

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TDP-43 condensation properties specify its RNA-binding and regulatory repertoire

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Mpe1 senses the binding of pre-mRNA and controls 3′ end processing by CPF

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Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration

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Alternative cleavage and polyadenylation generates downstream uncapped RNA isoforms with translation potential

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Cytoplasmic cleavage of IMPA1 3′ UTR is necessary for maintaining axon integrity

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Sites of transcription initiation drive mRNA isoform selection

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A Cancer-Specific Ubiquitin Ligase Drives mRNA Alternative Polyadenylation by Ubiquitinating the mRNA 3′ End Processing Complex

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The Circadian Clock Gene Circuit Controls Protein and Phosphoprotein Rhythms in Arabidopsis thaliana

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Parinarioidins A-B,unprecedented flavonoids from the bark of Brosimum parinarioides Ducke

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Predicting Successful Generation and Inhibition of Seizure-like Afterdischarges and Mapping Their Seizure Networks Using fMRI

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Opto-katanin,an optogenetic tool for localized,microtubule disassembly

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