PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate

1. Download : Download high-res image (106KB)
2. Download : Download full-size image

     

The LKB1-like Kinase Elm1 Controls Septin Hourglass Assembly and Stability by Regulating Filament Pairing

1. Download : Download high-res image (185KB)
2. Download : Download full-size image

     

Regulation of Multiple Fission and Cell-Cycle-Dependent Gene Expression by CDKA1 and the Rb-E2F Pathway in Chlamydomonas

1. Download : Download high-res image (102KB)
2. Download : Download full-size image

     

ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1

1. Download : Download high-res image (221KB)
2. Download : Download full-size image

     

Hydathode immunity protects the Arabidopsis leaf vasculature against colonization by bacterial pathogens

1. Download : Download high-res image (189KB)
2. Download : Download full-size image

     

The Arabidopsis TIR-NBS-LRR protein CSA1 guards BAK1-BIR3 homeostasis and mediates convergence of pattern- and effector-induced immune responses

1. Download : Download high-res image (117KB)
2. Download : Download full-size image

     

PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK

1. Download : Download high-res image (252KB)
2. Download : Download full-size image

     

MAP Kinase-Mediated Activation of RSK1 and MK2 Substrate Kinases

1. Download : Download high-res image (148KB)
2. Download : Download full-size image

     

Structural Basis for the High-Affinity Interaction between CASK and Mint1

1. Download : Download high-res image (268KB)
2. Download : Download full-size image

     

Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules

1. Download : Download high-res image (160KB)
2. Download : Download full-size image

     

Glioblastoma Cell Resistance to EGFR and MET Inhibition Can Be Overcome via Blockade of FGFR-SPRY2 Bypass Signaling

1. Download : Download high-res image (139KB)
2. Download : Download full-size image

     

An activity-dependent determinant of synapse elimination in the mammalian brain

1. Download : Download high-res image (209KB)
2. Download : Download full-size image

     

Chk1 dynamics in G2 phase upon replication stress predict daughter cell outcome

1. Download : Download high-res image (157KB)
2. Download : Download full-size image

     

Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture,phosphorylation, and ubiquitylation

1. Download : Download high-res image (142KB)
2. Download : Download full-size image

     

Phosphorylation of RIAM by src promotes integrin activation by unmasking the PH domain of RIAM

1. Download : Download high-res image (254KB)
2. Download : Download full-size image

     

Crystal structure of the CDK11 kinase domain bound to the small-molecule inhibitor OTS964

1. Download : Download high-res image (131KB)
2. Download : Download full-size image

     

Casein Kinase 1δ Stabilizes Mature Axons by Inhibiting Transcription Termination of Ankyrin

1. Download : Download high-res image (144KB)
2. Download : Download full-size image

     

TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation

1. Download : Download high-res image (146KB)
2. Download : Download full-size image

     

TORC1 Determines Fab1 Lipid Kinase Function at Signaling Endosomes and Vacuoles

1. Download : Download high-res image (118KB)
2. Download : Download full-size image

     

Mechanism of PINK1 activation by autophosphorylation and insights into assembly on the TOM complex

1. Download : Download high-res image (330KB)
2. Download : Download full-size image