Structure of detergent-activated BAK dimers derived from the inert monomer

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SFTSV Infection Induces BAK/BAX-Dependent Mitochondrial DNA Release to Trigger NLRP3 Inflammasome Activation

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Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis

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The Arabidopsis TIR-NBS-LRR protein CSA1 guards BAK1-BIR3 homeostasis and mediates convergence of pattern- and effector-induced immune responses

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Allelic variation in the Arabidopsis TNL CHS3/CSA1 immune receptor pair reveals two functional cell-death regulatory modes

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The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation

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Hydathode immunity protects the Arabidopsis leaf vasculature against colonization by bacterial pathogens

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Molecular basis for differential activation of p101 and p84 complexes of PI3Kγ by Ras and GPCRs

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A lncRNA fine-tunes salicylic acid biosynthesis to balance plant immunity and growth

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Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study

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HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural studies of class IB phosphoinositide 3-kinases

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Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of antagonistic chromatin marks

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Histone H3 lysine 4 trimethylation in sperm is transmitted to the embryo and associated with diet-induced phenotypes in the offspring

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Defining How Oncogenic and Developmental Mutations of PIK3R1 Alter the Regulation of Class IA Phosphoinositide 3-Kinases

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CpG island reconfiguration for the establishment and synchronization of polycomb functions upon exit from naive pluripotency

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Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling

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SH3BP4 promotes neuropilin-1 and α5-integrin endocytosis and is inhibited by Akt

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E6AP AZUL interaction with UBQLN1/2 in cells,condensates, and an AlphaFold-NMR integrated structure

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Cdc42 and its BORG2 and BORG3 effectors control the subcellular localization of septins between actin stress fibers and microtubules

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The Polycomb group protein MEDEA controls cell proliferation and embryonic patterning in Arabidopsis

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