Rewiring Ancient Residue Interaction Networks Drove the Evolution of Specificity in Steroid Receptors

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A genealogical estimate of genetic relationships

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Genomic analysis reveals cryptic diversity in aphelids and sheds light on the emergence of Fungi

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Mutational fitness landscape of human influenza H3N2 neuraminidase

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The Plant Mitochondrial TAT Pathway Is Essential for Complex III Biogenesis

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Prototypic SNARE Proteins Are Encoded in the Genomes of Heimdallarchaeota,Potentially Bridging the Gap between the Prokaryotes and Eukaryotes

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Phage-assisted evolution and protein engineering yield compact,efficient prime editors

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Evolutionary assembly of cooperating cell types in an animal chemical defense system

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Coevolving Plasmids Drive Gene Flow and Genome Plasticity in Host-Associated Intracellular Bacteria

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Evolutionary origins and interactomes of human,young microproteins and small peptides translated from short open reading frames

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Decoding the Functional Evolution of an Intramembrane Protease Superfamily by Statistical Coupling Analysis

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Leanchoiliidae reveals the ancestral organization of the stem euarthropod brain

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The role of causal knowledge in the evolution of traditional technology

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Determinants of Spike infectivity,processing, and neutralization in SARS-CoV-2 Omicron subvariants BA.1 and BA.2

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Computational Modeling of Protein Stability: Quantitative Analysis Reveals Solutions to Pervasive Problems

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Identification of novel bat coronaviruses sheds light on the evolutionary origins of SARS-CoV-2 and related viruses

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Deep mutational learning predicts ACE2 binding and antibody escape to combinatorial mutations in the SARS-CoV-2 receptor-binding domain

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The Early Evolution of Oral Poliovirus Vaccine Is Shaped by Strong Positive Selection and Tight Transmission Bottlenecks

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PDBcor: An automated correlation extraction calculator for multi-state protein structures

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Blind cavefish retain functional connectivity in the tectum despite loss of retinal input

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