共查询到20条相似文献,搜索用时 15 毫秒
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Cooperation of Sall4 and Sox8 transcription factors in the regulation of the chicken Sox3 gene during otic placode development 下载免费PDF全文
Yu Okamoto Naoko Nishimura Kazunari Matsuda Deshani C. Ranawakage Yusuke Kamachi Hisato Kondoh Masanori Uchikawa 《Development, growth & differentiation》2018,60(3):133-145
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Nicholas Rogers Pike-See Cheah Eva Szarek Kakoli Banerjee Jeffrey Schwartz Paul Thomas 《Gene expression patterns : GEP》2013,13(7):240-248
Previous studies have shown that Sox3 is expressed in nascent neuroprogenitor cells and is functionally required in mammals for development of the dorsal telencephalon and hypothalamus. However, Sox3 expression during embryonic and adult neurogenesis has not been examined in detail. Using a SOX3-specific antibody, we show that murine SOX3 expression is maintained throughout telencephalic neurogenesis and is restricted to progenitor cells with neuroepithelial and radial glial morphologies. We also demonstrate that SOX3 is expressed within the adult neurogenic regions and is coexpressed extensively with the neural stem cell marker SOX2 indicating that it is a lifelong marker of neuroprogenitor cells. In contrast to the telencephalon, Sox3 expression within the developing hypothalamus is upregulated in developing neurons and is maintained in a subset of differentiated hypothalamic cells through to adulthood. Together, these data show that Sox3 regulation is region-specific, consistent with it playing distinct biological roles in the dorsal telencephalon and hypothalamus. 相似文献
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The maize transcription factor EREB58 mediates the jasmonate‐induced production of sesquiterpene volatiles 下载免费PDF全文
Shengyan Li Hai Wang Fengqi Li Zhongliang Chen Xiuying Li Li Zhu Guirong Wang Jingjuan Yu Dafang Huang Zhihong Lang 《The Plant journal : for cell and molecular biology》2015,84(2):296-308
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Selective influence of Sox2 on POU transcription factor binding in embryonic and neural stem cells 下载免费PDF全文
Tapan Kumar Mistri Arun George Devasia Lee Thean Chu Wei Ping Ng Florian Halbritter Douglas Colby Ben Martynoga Simon R Tomlinson Ian Chambers Paul Robson Thorsten Wohland 《EMBO reports》2015,16(9):1177-1191
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Nitrate induction of root hair density is mediated by TGA1/TGA4 and CPC transcription factors in Arabidopsis thaliana 下载免费PDF全文
Javier Canales Orlando Contreras‐López José M. Álvarez Rodrigo A. Gutiérrez 《The Plant journal : for cell and molecular biology》2017,92(2):305-316
Root hairs are specialized cells that are important for nutrient uptake. It is well established that nutrients such as phosphate have a great influence on root hair development in many plant species. Here we investigated the role of nitrate on root hair development at a physiological and molecular level. We showed that nitrate increases root hair density in Arabidopsis thaliana. We found that two different root hair defective mutants have significantly less nitrate than wild‐type plants, suggesting that in A. thaliana root hairs have an important role in the capacity to acquire nitrate. Nitrate reductase‐null mutants exhibited nitrate‐dependent root hair phenotypes comparable with wild‐type plants, indicating that nitrate is the signal that leads to increased formation of root hairs. We examined the role of two key regulators of root hair cell fate, CPC and WER, in response to nitrate treatments. Phenotypic analyses of these mutants showed that CPC is essential for nitrate‐induced responses of root hair development. Moreover, we showed that NRT1.1 and TGA1/TGA4 are required for pathways that induce root hair development by suppression of longitudinal elongation of trichoblast cells in response to nitrate treatments. Our results prompted a model where nitrate signaling via TGA1/TGA4 directly regulates the CPC root hair cell fate specification gene to increase formation of root hairs in A. thaliana. 相似文献
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