A possibility to predict the severity of individual damage following the exposure to supralethal radiation dosage. Prediction of the clinical manifestation of radiation injury in laboratory animals by response to pre-exposure hypobaric hypoxia

The experiments on rats, dogs and monkeys exposed to radiation doses which cause intestinal and cerebral forms of radiation sickness have shown that the severity of a clinical state can be predicted by cardiovascular and endocrine changes when a pre-exposure test with moderate hypobaric hypoxia is performed. The goodness of fit of experimental data to the exposed result is up to 60-80%, still rising if a set of indices of the neuroendocrine status is used.