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1.
There are current attempts to replace the WADA test for pre-surgical evaluation of hemispheric language capabilities by one of the methods of functional brain imaging. Recent PET and fMRI studies using verbal cognitive tasks like verb generation, semantic monitoring or semantic (`deep') encoding of words showed asymmetries of activation in the fronto-lateral cortex. In a previous ERP study subjects were required to indicate whether pronounceable non-words and abstract geometric figures were presented for the first time (`new item') or whether they had been shown before (`old item'). Group analyses of this study showed significant material-specific hemispheric asymmetries with ERPs being more negative-going in recordings of the posterior part of the left hemisphere with verbal material (CP5/6) but more negative-going in recordings of the right hemisphere with the spatial material (P7/8). The aim of the present study was to test statistically ERP lateralization effects in individual healthy subjects as well as WADA-tested patients suffering from seizures of the mesio-temporal lobe (MTL). In all subjects ERP lateralization with verbal material was tested in the electrode pair CP5/6, and ERP lateralization with figures in the electrode pair P7/8. Statistical analyses of single trials showed that in 20 out of 24 subjects ERPs with verbal material started to be more negative-going in CP5 as compared to CP6 in the period between 100 and 200 ms after stimulus onset or the subsequent time epoch (200–300 ms). In one subject not CP5/6 but the closely adjacent electrode pair P7/P8 showed this verbal material-related hemispheric effect. In patients language dominance as indicated by ERPs was not always consistent with the data of the WADA test. In one patient with left MTL seizures ERPs with verbal material and figures were found to be significantly lateralized to the right hemisphere although the WADA test assigned this patient to have a language-dominant left hemisphere.  相似文献   

2.
In adult healthy right-handed subjects, the expression and degree of synchronization of the EEG alpha-range rhythmic components in different areas of the right and left hemispheres, were studied in a state of quiet wakefulness and during solving of verbal and spatial tasks presented in the visual field. The EEG of quiet wakefulness was characterized by different distribution of the alpha-range rhythmic components in the right and left hemispheres; in the right hemisphere low frequencies (7.5-10.5 c/s) were more expressed and more coherent; in the left one--the high frequencies (10.5-13.5 c/s). The solving of tasks was accompanied--along with a decrease of the whole alpha-range power spectra both in the right and the left hemispheres--by a local increase of synchronization of certain components of this range; the increase was specific to the hemisphere and the kind of task. The increase of synchronization of low-frequency components was observed in the right hemisphere during solving of the spatial task and that of the high-frequency components was noticed in the left hemisphere during solving of the verbal task. On the basis of the data on hemispheric specificity of electric activity synchronization of the alpha-rhythm, a suggestion is made about a different character of the functional integration of the structures of the right and left hemispheres in the process of solving of spatial and verbal tasks.  相似文献   

3.
In dichotic listening tasks, the (dominant) right ear's superiority in processing verbal stimuli has been attributed to its direct access to the linguistically dominant left hemisphere. The roles played by the extralinguistic factors, such as induced attentiveness and functional tuning of the auditory system, have not been carefully examined. The evidence for the facilitating effects of subcortical stimulation on processing dichotic stimuli is presented.  相似文献   

4.
Average evoked potentials (AEP) were recorded in practically healthy subjects to "meaningless" figures and letters, presented to different halves of the visual field. Analysis of the amplitudes of AEP late components to verbal and non-verbal stimuli reveals hemispheric asymmetry. A higher amplitude of the late positive evoked response (P300) to a "direct" stimulation both by verbal and non-verbal stimuli (in the contralateral field of vision) is recorded in the left hemisphere than in the right one. Similar stimulation of the right hemisphere does not reveal sucha difference. In the left hemisphere the P300 wave is of a clearly greater amplitude to a "direct" stimulation (contralateral visual field) than to an "indirect" one (ipsilateral visual field), regardless of the nature of the stimulus. No such difference is observed in the right hemisphere. The magnitude of the late negative wave (component N200) to non-verbal stimuli is greater in the right hemisphere both in response to "direct" and "indirect" stimulations. No intrahemispheric difference has been found in the amplitude of late evoked responses of the cerebral cortex to verbal and non-verbal stimuli.  相似文献   

5.
Effect of extrinsic motivation stimulating the most original problem solving during verbal and figurative divergent thinking was studied by EEG mapping. The righthanded university students (27 males and 26 females) participated in the experiments. An instruction "to create the most original solution" as compared to condition with an instruction "to create any solution" induced an increase in the baseline power of the alpha 1 and alpha 2 rhythms most pronounced in the posterior cortex. Task-related desynchronization of the alpha rhythms was higher but the beta-2 synchronization was lower after the former than after the latter instruction. Differences in the asymmetry of the alpha 1 and alpha 2 rhythms in the parietal and temporal regions of hemispheres suggested the right hemisphere dominance in intrinsic alertness and evoked activation related to divergent thinking. The findings were common and gender-independent in both figurative and verbal tasks suggesting a generalized influence of extrinsic motivation on creative activity.  相似文献   

6.
Verbal activity as the higher psychic brain function is performed as a result of systemic interactions of many cerebral structures and processes at various levels of organization. It is shown in this work that based on analysis of spatial-temporal relations of EEG waves during performance by adult examinees of such verbal-mnestic tasks as mental count, listening of a rhyme and its recalling, tests for verbal fluency, and search for homonyms there is revealed an enhancement of diagonal connections between activities of posterior parts of the left hemisphere cortex and anterior parts of the right hemisphere cortex. During performance by the examinees of recognition of grammatical or semantic errors in sentences the interhemispheric interactions on the whole are also enhanced statistically significantly, but without domination of diagonal interactions. These data show that during performance by examinees of verbal tasks of analytical character there also are simultaneously actualized intercentral interactions related to the functional system responsible for recognition not only of verbal, but also of any other stimuli. In children with motor alalia and dysarthria, disturbances of distant EEG connections were revealed either in the left or in the right hemisphere with a simultaneous enhancement of ipsilateral interactions in symmetrical parts of the contralateral hemisphere. A special attention is paid to significance of the degree of formation of neurophysiological systems of the general cerebral integration for realization of the verbal function.Translated from Zhurnal Evolyutsionnoi Biokhimii i Fiziologii, Vol. 40, No. 5, 2004, pp. 411–422.Original Russian Text Copyright © 2004 by Shepovalnikov, Tsitseroshin.To the 100-Anniversary of N. N. Traugott  相似文献   

7.
Abstract

48 right‐handed subjects performed verbal and spatial hemifield tachistoscopic tasks, half of them in spring and the other half in autumn. Significant differences were detected showing increased right visual field (left hemisphere) advantage in spring and increased left visual field (right hemisphere) advantage in autumn. Results may help to explain the reported seasonal propensity towards elevated mood in spring and towards depressed mood in autumn as related to the relative role of both hemispheres.  相似文献   

8.
9.
By means of graphic test (drawing on irregular grid) the preference of the space parts by patients in depressive and maniac states and also after the injection of psychotropic agents (antidepressants and neuroleptics) was studied. In depression and also after the injection of neuroleptics such modus of graphic test execution was revealed which can be conditionally determined as integral structuring of the space with the preference (high actuality) to its left part. The proofs are given that such type of test execution is typical for predominance of activation of the right hemisphere over the left one. In the manic state and after administration of improving mood drugs, a quite different type of grid filling is revealed, which is determined as fractional structuring of space with a decrease of actuality of its left part. Such type of space representation is typical for predominance of activation of the left hemisphere over the right one.  相似文献   

10.
Abstract

48 right‐handed subjects performed verbal and spatial hemifield tachistoscopic tasks, half of them during spring and the other half during autumn. Results showed increased visual field advantage both in performance speed and accuracy in the right visual field during spring and in the left visual field during autumn. This suggests a seasonal‐hemispheric shift favouring the left hemisphere during spring and the right hemisphere during autumn, and provides a clue to understanding seasonal variations in mood and affective states as related to variations in cognitive style.  相似文献   

11.
Change of biopotentials spatial synchronization under functional loads addressed predominantly to one or the other hemisphere (correlative analysis of the first EEG derivative of more than two thousands healthy subjects of various age), allowed to single out three phenotypes of hemispheric relations differing mainly by different types of information processing: right-hemispheric, left-hemispheric or mixed. Expressed EEG activation in both hemispheres (judged by alpha-index change) is manifest when the subject is presented with a task, the context of which does not correspond to the initially dominating type: in right-hemispheric--at solution of tasks, oriented to logical-verbal context and in left-hemispheric--to spatial-image one. The high level of non-specific EEG activation may be considered as an attempt of compensation of relative functional insufficiency of the right hemisphere systems in initially left-hemispheric or left-hemisphere systems in right-hemispheric individuals.  相似文献   

12.
Complex EEG and stabilography investigation with separate and simultaneous performance of motor (voluntary postural control) and cognitive (calculation) tasks has been performed in 20 healthy subjects (22 +/- 0.7 yo.). Specific spatial and frequency reactive changes have been revealed during motor task performance. These included increase of coherence in alpha-band for long pair of channels in right hemisphere as well as in symmetric parietal-occipital regions in both hemispheres. Cognitive task performance has been accompanied by coherence increase for low bands (delta- and theta-) with higher activation in left hemisphere and frontal regions. In dual tasks where both components were performed worse comparing to control, performance led to reactive spatial and frequency changes of both--motor and cognitive--tasks, though these changes were less than during separate task performance. Decrease of coherence in alphal-band in frontal areas appeared as a zone of "conflict of interest - interferention". In dual tasks with better performance of each component comparing to control EEG coherence increased in each specific area as well as in areas of "conflict of interest".  相似文献   

13.
Two parts of a geometrical figure are consecutively presented to healthy adult subjects in the left and right visual fields; the subjects have to compare them mentally and to decide whether these parts form a standard figure or not. Correctness of the reaction is controlled by a computer which lights up on the screen the words "good" or "error". The number of correct decisions of this visual-spatial task does not depend on the hemisphere to which information is addressed. The reaction time is substantially shorter if the information comes "directly" to the right hemisphere. Due to better training in the left hemisphere interhemispheric difference in reaction time gradually disappears in repeated tests. Training to mental "constructing" takes place only in the tests following positive feedback stimulus. Analysis of amplitude-temporal parameters of P300 wave shows that at correct decision of the visual-spatial task the level of activation in the right hemisphere is higher than in the left one.  相似文献   

14.
The problem is reviewed of sex differences and the brain organization of the visual-spatial and verbal-cognitive functions both in adults and in the 5–15-year old children. Characteristic of men are the integral strategy of the face image recognition, specialization of the right hemisphere for visual-spatial functions, and the tonic inhibitory effect of the right hemisphere on the left one. Typical of women are the fragmented type of the image recognition, the equality of the brain hemispheres functions at the unfamiliar face recognition, and predominance of the left hemisphere by accuracy of the object localization in the visual field. It is possible that the general strategy of the recognition in women is not realized due to the right hemisphere submitted to the interfering effect of the left hemisphere. Analysis of sex differences in distribution of verbal functions shows that the capability for the verbal learning at the age of 5 years and older is higher in girls than in boys. Such capability seems to be accounted for by the superiority of the left hemisphere in girls in this type of its activity and by its earlier development and maturation. The phenomenon of semantic paralexia appearing more often in boys is accounted for by inclusion of lexical-semantic fields of the right hemisphere symmetric areas in the verbal-cognitive activity There are reasons to believe that the higher capability in girls for the verbal learning is mainly due to processes of the auditory-verbal integration within the limits of the left hemisphere, whereas this verbal ability in boys depends on the relative predominance of the interhemispheric connections.  相似文献   

15.
Sex differences in electroencephalographic (EEG) correlates of creativity were studied using verbal and figural divergent tasks to be performed in accordance with the instructions to “give any solution” or “give an original solution.” The common effect was a greater activity of the right hemisphere, which did not depend on the sex, task type, or instructions for performance of the tasks. The α2 and β2 rhythms were the main EEG frequency correlates of creative thinking; the degree and sign of their reactivity depended on the aforementioned factors. Although the creative abilities in men and women were similar under test conditions, the EEG correlates of both figural and verbal tasks were sex-dependent. A high reactivity of the α2 rhythm was more marked during verbal creative thinking in women; and that of the β2 rhythm, during figural creative thinking in men. The instruction-related improvement of the critical selection of solutions was to a greater extent reflected by changes in the cortical activity, more pronounced in the frontal cortex in the women. Thus, the same creative productivity in men and women was mediated by different strategies of performance of both figural and verbal tasks, and the sex-related differences in these strategies remained even when the motivation for creativity was changed.  相似文献   

16.
Gender differences in EEG patterns associated with verbal creativity were studied by EEG mapping. The EEGs of 18 males and 21 females (right-handed university students) were recorded during a performance of Remote Associates Task (RAT) compared with the letter-fluency and simple associate's tasks. Gender differences were found in a factor structure of the indices of verbal thinking and a score of generating words was greater in women than men. No significant gender differences in originality of associations were revealed, however, gender-related differences in the EEG-patterns were found at the final and initial stages of RAT. In men, the beta2-power was increased in both hemispheres at the beginning of test. To the end of testing, the power of oscillations in the beta2 band increased only in the central part of the cortex. In women, the beta2-power was increased to a greater extent in the right than in the left hemisphere at the initial stage of task performance, whereas the final stage was characterized by a relative decrease in beta-activity in parietotemporal cortical regions and increase in the left prefrontal region. It is suggested that the verbal creative thinking in men is based mostly on "insight" strategy whereas women additionally involve the "intellectual" strategy.  相似文献   

17.
Averaged evoked potentials (AEP) to verbal (letters) and nonverbal (random shapes) stimuli exposed in the left and right visual fields were registered in healthy subjects with normal vision. Analysis of the later AEP latencies pointed to asymmetry in the temporal parameters of the interhemispheric interaction. The late AEP latency is shorter in the right hemisphere than in the left hemisphere. The difference is more pronounced in responses to nonverbal stimuli. The earlier development of the evoked potential in the right hemisphere (or the later one in the left hemisphere) accounts for the interhemispheric difference in the temporal parameters of the late AEP components. Comparison of the latency of the component P300 to verbal and nonverbal stimuli presented in the ipsilateral or the contralateral visual fields reveals a transfer of the results of the cortical processing of visual information in the course of interhemispheric interaction.  相似文献   

18.
The possible effects of continuous wave (CW) and pulse modulated (PM) electromagnetic field (EMF) on human cognition was studied in 36 healthy male subjects. They performed cognitive tasks while exposed to CW, PM, and sham EMF. The subjects performed the same tasks twice during each session; once with left-sided and once with right-sided exposure. The EMF conditions were spread across three testing sessions, each session separated by 1 week. The exposed hemisphere, EMF condition, and test order were counterbalanced over all subjects. We employed a double-blind design: both the subject and the experimenter were unaware of the EMF condition. The EMF was created with a signal generator connected via amplifier to a dummy phone antenna, creating a power output distribution similar to the original commercial mobile phone. The EMF had either a continuous power output of 0.25 W (CW) or pulsed power output with a mean of 0.25 W. An additional control group of 16 healthy male volunteers performed the same tasks without any exposure equipment to see if mere presence of the equipment could have affected the subjects' performance. No effects were found between the different EMF conditions, separate hemisphere exposures, or between the control and experimental group. In conclusion, the current results indicate that normal mobile phones have no discernible effect on human cognitive function as measured by behavioral tests.  相似文献   

19.
Hemispheric asymmetry of a wide range of functions is a hallmark of the human brain. The visual system has traditionally been thought of as symmetrically distributed in the brain, but a growing body of evidence has challenged this view. Some highly specific visual tasks have been shown to depend on hemispheric specialization. However, the possible lateralization of cerebral responses to a simple checkerboard visual stimulation has not been a focus of previous studies. To investigate this, we performed two sessions of blood-oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) in 54 healthy subjects during stimulation with a black and white checkerboard visual stimulus. While carefully excluding possible non-physiological causes of left-to-right bias, we compared the activation of the left and the right cerebral hemispheres and related this to grey matter volume, handedness, age, gender, ocular dominance, interocular difference in visual acuity, as well as line-bisection performance. We found a general lateralization of cerebral activation towards the right hemisphere of early visual cortical areas and areas of higher-level visual processing, involved in visuospatial attention, especially in top-down (i.e., goal-oriented) attentional processing. This right hemisphere lateralization was partly, but not completely, explained by an increased grey matter volume in the right hemisphere of the early visual areas. Difference in activation of the superior parietal lobule was correlated with subject age, suggesting a shift towards the left hemisphere with increasing age. Our findings suggest a right-hemispheric dominance of these areas, which could lend support to the generally observed leftward visual attentional bias and to the left hemifield advantage for some visual perception tasks.  相似文献   

20.
The effects of the activation level and subject's sex on bilateral skin conductance measures were studied. Thirty right-handed subjects (15 males and 15 females) were exposed to three types of stimulus conditions: rest-period, verbal task and spatial task. Results showed that no relationship was observed between EDA asymmetry and the increase in the activation level induced by the verbal and the spatial tasks. Males showed both higher SCRs and greater frequency of responses on the left than on the right hand. The direction of electrodermal asymmetry remained constant regardless of the stimulus conditions. It was concluded that sex differences are important in the study of EDA asymmetry and that this asymmetry appeared to depend on peripheral variations.  相似文献   

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