共查询到20条相似文献,搜索用时 15 毫秒
1.
Analysis of gene expression in cotton fiber initials 总被引:2,自引:0,他引:2
Background
Cotton (Gossypium hirsutum L.) fibers are trichomes that initiate from the ovule epidermis. Little is known about the developmental pathway causing fiber to differentiate from ovular epidermal cells even though limits on the number of cells that differentiate into fiber will limit yield. 相似文献2.
So-Jung Kwon Kyuyong Han Suhyun Jung Jong-Eun Lee Seongsoon Park Yong-Pil Cheon Jade Hyunjung Lim 《BMC biotechnology》2009,9(1):73
Background
MPG is a cell-permeable peptide with proven efficiency to deliver macromolecular cargoes into cells. In this work, we examined the efficacy of MPG as an N-terminal tag in a fusion protein to deliver a protein cargo and its mechanism of transduction. 相似文献3.
Yonnie Wu Richard C Laughlin David C Henry Darryl E Krueger JoAn S Hudson Cheng-Yi Kuan Jian He Jason Reppert Jeffrey P Tomkins 《BMC cell biology》2007,8(1):36
Background
Tubular shaped mammalian cells in response to dehydration have not been previously reported. This may be due to the invisibility of these cells in aqueous solution, and because sugars and salts added to the cell culture for manipulation of the osmotic conditions inhibit transformation of normal cells into tubular shaped structures. 相似文献4.
Background
During formation of the vertebrate central nervous system, the hindbrain is organized into segmental units, called rhombomeres (r). These cell-lineage restricted segments are separated by a subpopulation of cells known as boundary cells. Boundary cells display distinct molecular and cellular properties such as an elongated shape, enriched extracellular matrix components and a reduced proliferation rate compared to intra-rhombomeric cells. However, little is known regarding their functions and the mechanisms that regulate their formation. 相似文献5.
Françoise Botterel Karine Gross Oumaïma Ibrahim-Granet Khaled Khoufache Virginie Escabasse André Coste Catherine Cordonnier Estelle Escudier Stéphane Bretagne 《BMC microbiology》2008,8(1):97
Background
Invasive aspergillosis, which is mainly caused by the fungus Aspergillus fumigatus, is an increasing problem in immunocompromised patients. Infection occurs by inhalation of airborne conidia, which are first encountered by airway epithelial cells. Internalization of these conidia into the epithelial cells could serve as a portal of entry for this pathogenic fungus. 相似文献6.
Background:
One of the mechanisms that ensure cancer robustness is tumor heterogeneity, and its effects on tumor cells dynamics have to be taken into account when studying cancer progression. There is no unifying theoretical framework in mathematical modeling of carcinogenesis that would account for parametric heterogeneity. 相似文献7.
Background
Molecular cloning of functional immunoglobulin genes from single plasma cells is one of the most promising technologies for the rapid development of monoclonal antibody drugs. However, the proper insertion of PCR-amplified immunoglobulin genes into expression vectors remains an obstacle to the high-throughput production of recombinant monoclonal antibodies. 相似文献8.
Sujeong Jang Hyong-Ho Cho Yong-Bum Cho Jong-Seong Park Han-Seong Jeong 《BMC cell biology》2010,11(1):25
Background
Adult mesenchymal stem cells (MSCs) derived from adipose tissue have the capacity to differentiate into mesenchymal as well as endodermal and ectodermal cell lineage in vitro. We characterized the multipotent ability of human adipose tissue-derived stem cells (hADSCs) as MSCs and investigated the neural differentiation potential of these cells. 相似文献9.
Stefania Violini Paola Ramelli Laura F Pisani Chiara Gorni Paola Mariani 《BMC cell biology》2009,10(1):29-10
Background
Mesenchymal stem cells (MSCs) have been recently investigated for their potential use in regenerative medicine. MSCs, in particular, have great potential, as in various reports they have shown pluripotency for differentiating into many different cell types. However, the ability of MSCs to differentiate into tendon cells in vitro has not been fully investigated. 相似文献10.
Background
During normal development, cells undergo a unidirectional course of differentiation that progressively decreases the number of cell types they can potentially become. Pluripotent stem cells can differentiate into several types of cells, but terminally differentiated cells cannot differentiate any further. A fundamental problem in stem cell biology is the characterization of the difference in cellular states, e.g., gene expression profiles, between pluripotent stem cells and terminally differentiated cells. 相似文献11.
Sean HJ Kim Sunwoo Park Keith Mostov Jayanta Debnath C Anthony Hunt 《Theoretical biology & medical modelling》2009,6(1):8-21
Background
When grown in three-dimensional (3D) cultures, epithelial cells typically form cystic organoids that recapitulate cardinal features of in vivo epithelial structures. Characterizing essential cell actions and their roles, which constitute the system's dynamic phenotype, is critical to gaining deeper insight into the cystogenesis phenomena. 相似文献12.
Fu Huamei Björkman Lena Janmey Paul Karlsson Anna Karlsson Jennie Movitz Charlotta Dahlgren Claes 《BMC cell biology》2004,5(1):1-19
Background
Upon serial passaging of mouse skeletal muscle cells, a small number of cells will spontaneously develop the ability to proliferate indefinitely while retaining the ability to differentiate into multinucleate myotubes. Possible gene changes that could underlie myogenic cell immortalization and their possible effects on myogenesis had not been examined. 相似文献13.
Andrew L Laslett Sean Grimmond Brooke Gardiner Lincon Stamp Adelia Lin Susan M Hawes Sam Wormald David Nikolic-Paterson David Haylock Martin F Pera 《BMC developmental biology》2007,7(1):12
Background
The mechanisms responsible for the maintenance of pluripotency in human embryonic stem cells, and those that drive their commitment into particular differentiation lineages, are poorly understood. In fact, even our knowledge of the phenotype of hESC is limited, because the immunological and molecular criteria presently used to define this phenotype describe the properties of a heterogeneous population of cells. 相似文献14.
Zahia Hamidouche Olivia Fromigué Jochen Ringe Thomas Häupl Pierre J Marie 《BMC cell biology》2010,11(1):44
Background
The potential of mesenchymal stromal cells (MSCs) to differentiate into functional bone forming cells provides an important tool for bone regeneration. The identification of factors that trigger osteoblast differentiation in MSCs is therefore critical to promote the osteogenic potential of human MSCs. In this study, we used microarray analysis to identify signalling molecules that promote osteogenic differentiation in human bone marrow stroma derived MSCs. 相似文献15.
Background
Silver has long been known to have antimicrobial activity. To incorporate this property into multiple applications, a silver-impregnated cellulose (SIC) with low cytotoxicity to human cells was developed. SIC differs from other silver treatment methods in that the leaching of silver particles is non-existent and the release of ionic silver is highly controlled. 相似文献16.
Background
Mammalian cells transform into individual tubular straw cells naturally in tissues and in response to desiccation related stress in vitro. The transformation event is characterized by a dramatic cellular deformation process which includes: condensation of certain cellular materials into a much smaller tubular structure, synthesis of a tubular wall and growth of filamentous extensions. This study continues the characterization of straw cells in blood, as well as the mechanisms of tubular transformation in response to stress; with specific emphasis placed on investigating whether tubular transformation shares the same signaling pathway as apoptosis. 相似文献17.
Comparative transfection of DNA into primary and transformed mammalian cells from different lineages
Rosalie Maurisse David De Semir Hamid Emamekhoo Babak Bedayat Alireza Abdolmohammadi Hooman Parsi Dieter C Gruenert 《BMC biotechnology》2010,10(1):9
Background
The delivery of DNA into human cells has been the basis of advances in the understanding of gene function and the development of genetic therapies. Numerous chemical and physical approaches have been used to deliver the DNA, but their efficacy has been variable and is highly dependent on the cell type to be transfected. 相似文献18.
Background
Actin is an ancient molecule that shows more than 90% amino acid homology between mammalian and plant actins. The regions of the actin molecule that are involved in F-actin assembly are largely conserved, and it is likely that mammalian actin is able to incorporate into microfilaments in plant cells but there is no experimental evidence until now. 相似文献19.
Background
Cell-permeant Cre DNA site-specific recombinases provide an easily controlled means to regulate gene structure and function in living cells. Since recombination provides a stable and unambiguous record of protein uptake, the enzyme may also be used for quantitative studies of cis- and trans-acting factors that influence the delivery of proteins into cells. 相似文献20.