The Structural Basis for Low Conductance in the Membrane Protein VDAC upon β-NADH Binding and Voltage Gating

1. Download : Download high-res image (148KB)
2. Download : Download full-size image

     

Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding

1. Download : Download high-res image (338KB)
2. Download : Download full-size image

     

The accuracy of protein structures in solution determined by AlphaFold and NMR

1. Download : Download high-res image (139KB)
2. Download : Download full-size image

     

Structural characterization of human tryptophan hydroxylase 2 reveals that L-Phe is superior to L-Trp as the regulatory domain ligand

1. Download : Download high-res image (253KB)
2. Download : Download full-size image

     

Transient association between proteins elicits alteration of dynamics at sites far away from interfaces

1. Download : Download high-res image (170KB)
2. Download : Download full-size image

     

Computational studies of the principle of dynamic-change-driven protein interactions

1. Download : Download high-res image (117KB)
2. Download : Download full-size image

     

Modeling of protein conformational changes with Rosetta guided by limited experimental data

1. Download : Download high-res image (187KB)
2. Download : Download full-size image

     

Rewiring Ancient Residue Interaction Networks Drove the Evolution of Specificity in Steroid Receptors

1. Download : Download high-res image (108KB)
2. Download : Download full-size image

     

Inherent backbone dynamics fine-tune the functional plasticity of Tudor domains

1. Download : Download high-res image (162KB)
2. Download : Download full-size image

     

The structural heterogeneity of α-synuclein is governed by several distinct subpopulations with interconversion times slower than milliseconds

1. Download : Download high-res image (81KB)
2. Download : Download full-size image

     

Interactions of a Bacterial RND Transporter with a Transmembrane Small Protein in a Lipid Environment

1. Download : Download high-res image (350KB)
2. Download : Download full-size image

     

Structure of the human signal peptidase complex reveals the determinants for signal peptide cleavage

1. Download : Download high-res image (350KB)
2. Download : Download full-size image

     

How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view

1. Download : Download high-res image (227KB)
2. Download : Download full-size image

     

An Efficient Timer and Sizer of Biomacromolecular Motions

1. Download : Download high-res image (92KB)
2. Download : Download full-size image

     

Regulation of GTPase function by autophosphorylation

1. Download : Download high-res image (162KB)
2. Download : Download full-size image

     

Distinct Allosteric Networks Underlie Mechanistic Speciation of ABC Transporters

1. Download : Download high-res image (140KB)
2. Download : Download full-size image

     

A universal allosteric mechanism for G protein activation

1. Download : Download high-res image (229KB)
2. Download : Download full-size image

     

Protein Motional Details Revealed by Complementary Structural Biology Techniques

1. Download : Download high-res image (236KB)
2. Download : Download full-size image

     

Native state fluctuations in a peroxiredoxin active site match motions needed for catalysis

1. Download : Download high-res image (171KB)
2. Download : Download full-size image

     

Cooperative mechanics of PR65 scaffold underlies the allosteric regulation of the phosphatase PP2A

1. Download : Download high-res image (259KB)
2. Download : Download full-size image