A single residue confers selective loss of sugar sensing in wrynecks

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Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells

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Definition of a small core transcriptional circuit regulated by AML1-ETO

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Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling

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Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells

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The Arabidopsis mature endosperm promotes seedling cuticle formation via release of sulfated peptides

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Evolutionary assembly of cooperating cell types in an animal chemical defense system

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Structural insights into the human D1 and D2 dopamine receptor signaling complexes

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Organized B cell sites in cartilaginous fishes reveal the evolutionary foundation of germinal centers

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FOXO1 constrains activation and regulates senescence in CD8 T cells

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Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells

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Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis

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ATR Protects the Genome against R Loops through a MUS81-Triggered Feedback Loop

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A synaptic temperature sensor for body cooling

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Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes

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A unified atlas of CD8 T cell dysfunctional states in cancer and infection

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In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer

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The role of causal knowledge in the evolution of traditional technology

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Conformational surveillance of Orai1 by a rhomboid intramembrane protease prevents inappropriate CRAC channel activation

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EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells

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