Images of bacterial cells stained with KK114 dye and visualized with STED microscopy. On the monitor: large field of view of B. subtilis cells, the KK114 ball‐and‐stick model and the schematics of the STED setup. Different space‐filling representations of the FtsZ protein are also shown. Further details can be found in the article by Massimiliano Lucidi, Radu Hristu, Lorenzo Nichele, George A. Stanciu, Denis E. Tranca, Alina Maria Holban, Paolo Visca, Stefan G. Stanciu, and Gabriella Cincotti ( e202000097 ).
The first post-pandemic face-to-face international conference in Biophotonics took place in Porto in April 2022. High quality and inspiring presentations have been delivered by leading scientists and internationally recognized professionals, standing on the forefront of Biophotonics research and representing broadness of the field. A selected number of these presentations resulted in the papers that are presented in this special issue. The cover images were selected from Hoffer et al., Lomanovskaya et al., Li et al., and Burton et al. (clockwise).
We report on an attempt to increase the therapeutic effect of photodynamic therapy using a lipid nanoparticle (LNP). The findings indicate that the internal structure of the LNPs change depending on the amount of photosensitizer in the particle. The photoactivity and cell-killing effect of photosensitizer also changed with increasing amount of cargo, suggesting that the internal structure of the LNP is an important factor that affect the therapeutic effect. Further details can be found in the article by Fumika Kubota, Satrialdi, Yuta Takano, Masatoshi Maeki, Manabu Tokeshi, Hideyoshi Harashima, and Yuma Yamada ( e202200119 ).
