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Rewiring of the Fruit Metabolome in Tomato Breeding 总被引:6,自引:0,他引:6
Guangtao Zhu Shouchuang Wang Zejun Huang Shuaibin Zhang Qinggang Liao Chunzhi Zhang Tao Lin Mao Qin Meng Peng Chenkun Yang Xue Cao Xu Han Xiaoxuan Wang Esther van der Knaap Zhonghua Zhang Xia Cui Harry Klee Alisdair R. Fernie Sanwen Huang 《Cell》2018,172(1-2):249-261.e12
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Deng Biao Wang Xuan Long Xing Fang Ren Zhou Shuangyun Zhang Ji Peng Xiaolu An Zhenyu Huang Weixiong Tang Wenzhong Gao Yining Yao Jinyan 《Journal of Plant Growth Regulation》2022,41(6):2386-2405
Journal of Plant Growth Regulation - Gibberellin (GA), auxin (IAA) and brassinosteroid (BR) are indispensable in the process of plant growth and development. Currently, research on the regulatory... 相似文献
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Hana Totary-Jain Despina Sanoudou Iddo Z. Ben-Dov Cula N. Dautriche Paolo Guarnieri Steven O. Marx Thomas Tuschl Andrew R. Marks 《The Journal of biological chemistry》2013,288(9):6034-6044
The mammalian target of rapamycin (mTOR) is a central regulator of cell proliferation that is often deregulated in cancer. Inhibitors of mTOR, including rapamycin and its analogues, are being evaluated as antitumor agents. For their promise to be fulfilled, it is of paramount importance to identify the mechanisms of resistance and develop novel therapies to overcome it. Given the emerging role of microRNAs (miRNAs) in tumorigenesis, we hypothesized that miRNAs could play important roles in the response of tumors to mTOR inhibitors. Long-term rapamycin treatment showed extensive reprogramming of miRNA expression, characterized by up-regulation of miR-17–92 and related clusters and down-regulation of tumor suppressor miRNAs. Inhibition of members of the miR-17–92 clusters or delivery of tumor suppressor miRNAs restored sensitivity to rapamycin. This study identifies miRNAs as new downstream components of the mTOR-signaling pathway, which may determine the response of tumors to mTOR inhibitors. It also identifies potential markers to assess the efficacy of treatment and provides novel therapeutic targets to treat rapamycin-resistant tumors. 相似文献
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Xing J. C. Zhao B. Q. Dong J. Liu C. Wen Z. G. Zhu X. M. Ding H. R. He T. T. Yang H. Wang M. W. Hong L. Z. 《Russian Journal of Plant Physiology》2020,67(1):146-152
Russian Journal of Plant Physiology - The purslane Portulaca oleraceae L. can tolerant high saline stress and has been developed as a seawater-irrigated vegetable. Currently, the underlying... 相似文献
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Min Gab Kim 《Journal of Plant Biology》2010,53(1):70-78
Plants defend themselves by inducing sophisticated multilevel defense responses against pathogenic attack. The first line
of defense against microbial pathogens is the process of nonself-recognition, which mediates the activation of the necessary
defense repertoire. The hypersensitive response (HR), a macroscopic collapse of plant leaves in primary infection site, is
one of such plant resistance responses. Subsequently, the HR triggers a general resistance mechanism called systemic acquired
resistance (SAR), rendering uninfected parts of the plants less sensitive to further pathogenic attacks. Here, we show that
SIZ1 mutation-mediated preexisting SAR attenuates HR-associated cell death in Arabidopsis thaliana. In siz1 mutant, the amount of PR1 and PR5 stayed high level, and the growth of pathogenic bacteria Pseudomonas syringae pv. maculicola (Pma) strain M6CΔE was reduced. Early callose deposition, spontaneous formation of microscopic cell death, and reactive oxygen
species (ROS) were also observed in siz1 mutant. 相似文献
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Russian Journal of Plant Physiology - Τhe tomato plant (Lycopersicon esculentum Mill.) is particularly vulnerable to chilling injury. Hence research on screening out the cold-resistance gene... 相似文献
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植物代谢组学研究进展 总被引:2,自引:0,他引:2
代谢组学是继基因组学、转录组学和蛋白质组学之后发展起来的一门学科,通过对细胞内的基因表达最终代谢产物的定性和定量分析以及定义细胞或器官的生化表现类型来解释功能基因的表达过程。文中就代谢组学的发展历史、主要研究内容、技术特点、数据处理过程及在植物领域中的应用的最新进展几方面进行阐述,以供读者参考。 相似文献