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Adem Atmaca 《The International Journal of Life Cycle Assessment》2016,21(6):831-846
Purpose
Buildings are responsible for more than 40 % of global energy used, and as much as 30 % of global greenhouse gas emissions. In order to quantify the energy and material inputs and environmental releases associated with each stage of construction sector, life cycle energy, greenhouse gas emissions, and cost analysis of contemporary residential buildings have been conducted within two parts.Methods
This paper is the first part of the study which includes the literature review and methodology used for such a comprehensive analysis. It was determined that there are three basic methods used in life cycle analysis: process analysis, input–output (I–O) analysis, and hybrid analysis. In this study, Inventory of Carbon and Energy (ICE) is used for the calculation of primary energy requirements and greenhouse gas emissions. The second part of this study is about the application of the methodology which considers two actual buildings constructed in Gaziantep, Turkey.Results and discussion
The proposed research focused on building construction, operating, and demolition phases. Energy efficiency, emission parameters, and costs are defined for the building per square meter basis. It is seen that the primary energy use and emissions of residential buildings around the world falls in the range of about 10 to 40 GJ/m2 and 1–10 t CO2/m2 respectively.Conclusions
The literature survey demonstrates that there are limited number of studies about life cycle cost assessment (LCCA) of residential buildings in the world. It was decided to use the ICE database as it is one of the most comprehensive databases for building materials, globally. The results of the study show that minimizing energy, material, and land use by considering potential impacts to the environment on a life cycle basis are the basic steps in designing an energy-efficient and environmental-friendly building.4.
Des Spence 《BMJ (Clinical research ed.)》2005,330(7491):607
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The lack of newly developed antibiotics, together with the increase in multi-resistance of relevant pathogenic bacteria in the last decades, represents an alarming signal for human health care worldwide. The number of severely infected persons increases not only in developing but also in highly industrialized countries. This relates in first line to the most severe form of a bacterial infection, sepsis and the septic shock syndrome, with high mortality on critical care units. No particular anti-sepsis drug is available, and the therapy with conventional antibiotics more and more fails to provide a survival benefit. Due to the fact that the pharmaceutical industry has withdrawn to a high degree from the development of anti-infectious agents, a huge challenge for health care is approaching in the 21 st century. In this article, these problems are outlined and possible alternatives are presented which may be helpful to solve the problem. 相似文献
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Robbert Misdorp Frank Steyaert John de Ronde Frank Hallie 《Helgoland Marine Research》1989,43(3-4):333-345
This paper deals with the methods and results of monitoring sea level (tidal gauges) and with the analysis of depth sounding data. Possible future monitoring by menas of remote sensing techniques will be presented. Some trends, based on water level and morphological monitoring, have been established in the western part of the Dutch Wadden sea: (a) the relative mean sea level is rising persistently by 15 cm/century, observed since the middle of the 19th century. The tidal range is increasing as well; (b) the cross-sectional areas of the most western Dutch Wadden tidal inlets have been increasing over the last two centuries; (c) the intertidal zones of the Texelstroom and Vliestroom tidal basins have shown an increase of surface area over the last decades. The Borndiep tidal basin shows a decrease of 4% of the area shallower than 5 m — Dutch Ordinance Level (DOL) over the last two centuries. Several factors prevent serious predictions about future morphological developments of the tidal Wadden flats: (a) man induced interfering factors, e.g. the construction of the harbour revetments of Den Helder, the construction of the Enclosure Dike and construction of sand drift dikes stabilising the Wadden islands; (b) the limited scope of the present analysis that deals only with the western part of the Dutch Wadden Sea. Presented at the VI International Wadden Sea Symposium (Biologische Anstalt Helgoland, Wattenmeerstation Sylt, D-2282 List, FRG, 1–4 November 1988) 相似文献
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Garland E. Allen 《Journal of the history of biology》1991,24(3):529-536
Nicholas Russell, Like Engend'ring Like: Heredity and Animal Breeding in Early Modern England (Cambridge: Cambridge University Press, 1986); Deborah Fitzgerald, The Business of Breeding: Hybrid Corn in Illinois, 1890–1940 (Ithaca, N.Y.: Cornell University Press, 1989); Jack R. Kloppenburg, First the Seed: The Political Economy of Plant Biotechnology, 1492–2000 (New York: Cambridge University Press, 1988). 相似文献
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Raquel Santos Jorge Troy R. Hawkins Edgar G. Hertwich 《The International Journal of Life Cycle Assessment》2012,17(1):9-15
Purpose
The purpose of this study is to provide life cycle inventory data and results for components of electrical grids to the larger community of life cycle assessment practitioners. This article is the first in a series of two, each focusing on different components of power grids. In part 1, the objects under scope are power lines and cables. Systems for overhead, underground, and subsea transmission are modeled here, including HVDC systems used in long-distance transmission. 相似文献10.
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Mitchell G. Weiss 《Culture, medicine and psychiatry》1985,9(2):121-200
Substantial interactions between tropical diseases and psychiatric illness have long been recognized, but the impact of biological factors in the field of cross-cultural psychiatry has been less well studied than psychosocial factors. In reviewing the literature at the intersection of tropical medicine and psychiatry in order to summarize the existing data base in this field, a generalized interactive model informed by the theoretical contributions of George Engel, the WHO Scientific Working Group on Social and Economic Research, Arthur Kleinman, P. M. Yap, Edward Sapir and others has been developed to serve as a conceptual framework for this analysis of the literature and to guide further research. The clinical literature of tropical medicine and psychiatry which recognizes the significance of concurrent tropical disease and mental disorders is reviewed along with the more specific literature on malaria and concomitant psychiatric illness. Many authors have focused on the role of organic mental disorders, especially in connection with cerebral malaria, but several have also addressed psychosocial parameters through which the interrelationship between malaria and a full range of mental disorders is also mediated. The effects of malaria may serve as biological, psychological or social stressors operating in a cultural context which precipitate or shape features of psychiatric symptomatology. Psychiatric illness may likewise precipitate an episode of malaria with typical symptoms in a patient with a previously subclinical infection. Implications of the literature and this generalized interactive model are considered as they apply to clinical practice, public health and the application of social science theory in medicine.[/p] 相似文献
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Heike Wägele Annette Klussmann-Kolb Eva Verbeek Michael Schrödl 《Organisms Diversity & Evolution》2014,14(1):133-149
Opisthobranchia have experienced an unsettled taxonomic history. At the moment their taxonomy is in state of dramatic flux as recent phylogenetic studies have revealed traditional Opisthobranchia to be paraphyletic or even polyphyletic, allocating some traditional opisthobranch taxa to other groups of Heterobranchia, e.g. Pulmonata. Here we review the history of Opisthobranchia and their subgroups, explain their traditionally proposed relationships, and outline the most recent phylogenetic analyses based on various methods (morphology, single gene and multiple gene analyses, as well as genomic data). We also present a phylogenetic hypothesis on Heterobranchia that, according to the latest results, represents a consensus and is the most probable one available to date. The proposed phylogeny supports the Acteonoidea outside of monophyletic Euthyneura, the basal euthyneuran split into Nudipleura (Nudibranchia plus Pleurobranchoidea) and the recently established taxon Tectipleura. The latter divides into the Euopisthobranchia, containing most of the major traditional opisthobranch clades, and the Panpulmonata, with a mix of the former opisthobranch, putative allogastropod and pulmonate taxa. This “new euthyneuran tree” rejects the traditional taxa Opisthobranchia and Pulmonata, and, in particular, has profound implications for preconceived textbook scenarios of opisthobranch and pulmonate evolution, which must now be reconsidered. In the absence of systematic barriers, research communities—which have traditionally investigated marine and non-marine heterobranchs separately—need to interact and finally merge for the sake of science. 相似文献
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Pranav Danthi Caroline M. Coffey John S. L. Parker Ty W. Abel Terence S. Dermody 《PLoS pathogens》2008,4(12)
Apoptosis plays an important role in the pathogenesis of reovirus encephalitis. Reovirus outer-capsid protein μ1, which functions to penetrate host cell membranes during viral entry, is the primary regulator of apoptosis following reovirus infection. Ectopic expression of full-length and truncated forms of μ1 indicates that the μ1 ϕ domain is sufficient to elicit a cell death response. To evaluate the contribution of the μ1 ϕ domain to the induction of apoptosis following reovirus infection, ϕ mutant viruses were generated by reverse genetics and analyzed for the capacity to penetrate cell membranes and elicit apoptosis. We found that mutations in ϕ diminish reovirus membrane penetration efficiency by preventing conformational changes that lead to generation of key reovirus entry intermediates. Independent of effects on membrane penetration, amino acid substitutions in ϕ affect the apoptotic potential of reovirus, suggesting that ϕ initiates apoptosis subsequent to cytosolic delivery. In comparison to wild-type virus, apoptosis-defective ϕ mutant viruses display diminished neurovirulence following intracranial inoculation of newborn mice. These results indicate that the ϕ domain of μ1 plays an important regulatory role in reovirus-induced apoptosis and disease. 相似文献
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Andrade Edilene Pereira de Araújo Nunes Ana Bárbara de Freitas Alves Kilvia Ugaya Cássia Maria Lie da Costa Alencar Mateus de Lima Santos Tayane da Silva Barros Viviane Pastor Amandine Valérie de Figueirêdo Maria Cléa Brito 《The International Journal of Life Cycle Assessment》2020,25(12):2342-2358
The International Journal of Life Cycle Assessment - This paper presents the regionalized water scarcity characterization factors (CFs) of the available water remaining (AWARE) model, which was... 相似文献
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Joana Gon?alves Luís Vasco Louro Ivone Ribeiro ?ngelo Oliveira Carla Castro 《Reports of Practical Oncology and Radiotherapy》2014,19(5):343-346
Granulocytic sarcomas are rare tumors that can present in innumerous locations; thus there is very little clinical experience with these cases. Therefore there is no consensus on which is the best treatment for patients with this malignancy.The authors present a case of a female with a granulocytic sarcoma of the breast and review the literature for the role of radiotherapy in the management of this clinical entity. 相似文献
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Przemyslaw Kurczewski 《The International Journal of Life Cycle Assessment》2014,19(3):593-600
Purpose
This article is the first of a series of articles presenting the results of research on the implementation of life cycle management tools in small- and medium-sized companies in Poland. This work is part of a project financed by the Polish Agency for Enterprise Development (PAED) which began in February 2011. It was carried out by the Wielkopolska Quality Institute—a business environment institution associated with the Polish Centre for Life Cycle Assessment (PCLCA). The main practical objective of the project was to support small and medium enterprises (SMEs) in their business development, e.g. by expanding their horizons beyond the sphere of their operation and identifying new areas for improvement and promotion of the products and services on offer. These publications are a voice in the discussion on the opportunities and pertinence of implementing life cycle thinking (LCT) in small- and medium-sized enterprises and an attempt to identify potential barriers arising from specific characteristics of SMEs which could hinder or even prevent the effective implementation of life cycle techniques. Part 1 presents the situation of SMEs in Poland, general objectives of the project and organisation of the survey process.Methods
It was decided to carry out research on the effectiveness of the implementation of LCA and life cycle costing (LCC) in organisations that had received financial support for the implementation of life cycle techniques. Financial constraints, which might potentially be a reason for limited interest in LC techniques among SMEs in Poland, were taken into account. Thus, financial support provided an opportunity for the project to obtain information from a wide range of companies, not only from those companies that were particularly aware of the benefits of LC techniques or had a very good financial situation. Research based on the method of individual in-depth interviews was preceded by an analysis of literature showing the status of SMEs in Poland. Given the results, the project objectives were formulated and the ways of conducting the research were defined.Results and discussion
The comparison of Polish SMEs with the same category of companies in the EU shows some similarities, such as the percentage of companies engaged in various businesses. The differences are expressed primarily in the financial potential, which in the case of Polish SMEs, is significantly smaller than the average in the EU. In the SME sector, there are less than half as many small businesses in Poland than in the EU. There are, however, many more microbusinesses in Poland. An evaluation of the prevalence of LCA and LCC techniques indicates that they are used by just 3 % of Polish SMEs, which is a very small proportion compared to the more than 50 % of SMEs taking any environmental measures. Information collected on specific details of Polish SMEs was used to identify the target group and develop a survey questionnaire which aimed to audit, among other things, the approach to environmental and economic analyses in the past and the approach to the LCA and/or LCC analyses that were implemented from the point of view of difficulties in their implementation and potential use of the results.Conclusions
Part 1 of the series of articles demonstrates a marginal-scale dissemination of life cycle management techniques among Polish SMEs. Companies definitely prefer to introduce relatively simple solutions that do not require specialised knowledge or unnecessary costs, e.g. they introduce energy-saving bulbs and waste segregation. Only a small percentage of companies implement more complex activities, and most commonly, these are medium-sized companies with greater financial and human capital. So what should be done to make SMEs use life cycle techniques more frequently? Is it appropriate to make changes in the methodology and life cycle techniques as such, or should, rather, the incentive for SMEs to use LCT come from outside as a requirement of public institutions or suppliers in a supply chain? Answers to these questions are provided in the research conclusions presented in parts 2 and 3 of the series of articles. 相似文献19.
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《The International journal of biochemistry》1981,13(5):621-636
A table of molar absorptivity and A1%1cm values for more than 220 proteins is given. The conditions used to obtain these values and references to the original literature are also given. 相似文献