Tumour physics

During the cell division dynamic processes take place, the origin of which are to find in the physical characteristics of cell components. The most important characteristics are the electrical charge and the energy of the moving base components in a viscous cytoplasm. The interactions between the components lead as well known, to the emergence of hydrogen bonds between two DNA strands. The computations show that the strength of these bindings depends on three factors: first it is dependent on the length of a monotonous sequence, second it is dependent on the viscosity of the cytoplasm, and third it is dependent on the replication speed. In the study in detail is stated, how it affects the effectiveness of the DNA repair mechanism, mutation susceptibility, and thus also affects the cancer susceptibility.     

Plasminogen-activator-producing Tumour

In a patient with giant-cell carcinoma of the lung a secondary tumour deposit in the arm was incised and bled for three weeks. Investigations showed the tumour to be rich in plasminogen activator. Haemostasis in the tumour was achieved with aminocaproic acid therapy. For a period the plasminogen-activator properties were retained in cell culture of the tumour.