Explaining religious differences in immigrants' gender role attitudes: the changing impact of origin country and individual religiosity

Religion is often perceived as one of the main barriers to immigrant integration in Europe. By focusing on the contested area of immigrants' gender role attitudes, this study analyses data of first- and second-generation immigrants from multiple origin countries and of different religious affiliations in comparison to the native population. It shows that higher levels of religiosity can explain immigrants' more traditional attitudes to some extent, but that origin country socialization acts as an important additional determinant of attitudes of the first generation. Among second-generation migrants, only Muslims continue to hold more traditional attitudes. Acculturation for longer-staying migrants is partly explained by declining religiosity, with some evidence for a decoupling of attitudes from religious beliefs among female migrants in particular. Intergenerational change, on the other hand, cannot be attributed to a decline in the role of religiosity.     

Changes in salivary testosterone concentrations and subsequent voluntary squat performance following the presentation of short video clips

Previous studies have shown that visual images can produce rapid changes in testosterone concentrations. We explored the acute effects of video clips on salivary testosterone and cortisol concentrations and subsequent voluntary squat performance in highly trained male athletes (n=12). Saliva samples were collected on 6 occasions immediately before and 15 min after watching a brief video clip (approximately 4 min in duration) on a computer screen. The watching of a sad, erotic, aggressive, training motivational, humorous or a neutral control clip was randomised. Subjects then performed a squat workout aimed at producing a 3 repetition maximum (3RM) lift. Significant (P<0.001) relative (%) increases in testosterone concentrations were noted with watching the erotic, humorous, aggressive and training videos (versus control and sad), with testosterone decreasing significantly (versus control) after the sad clip. The aggressive video also produced an elevated cortisol response (% change) and more so than the control and humorous videos (P<0.001). A significant (P<0.003) improvement in 3RM performance was noted after the erotic, aggressive and training clips (versus control). A strong within-individual correlation (mean r=0.85) was also noted between the relative changes in testosterone and the 3RM squats across all video sessions (P<0.001). In conclusion, different video clips were associated with different changes in salivary free hormone concentrations and the relative changes in testosterone closely mapped 3RM squat performance in a group of highly trained males. Thus, speculatively, using short video presentations in the pre-workout environment offers an opportunity for understanding the outcomes of hormonal change, athlete behaviour and subsequent voluntary performance.     

Public attitudes and willingness to pay toward the conservation of Crested Ibis: Insights for management

In order to better design conservation programs to conserve threatened species, social, economic and political factors must be carefully considered. The wild population of the endangered Crested Ibis (Nipponia nippon) is currently only distributed in Yangxian County, Shaanxi province of China, and as the gradual dispersal of its population from the mountains to the plains, the possibility of human-wildlife interaction has increased, which poses certain challenges for conservation and management. Here, we used a questionnaire to investigate public attitudes and willingness to pay (WTP) toward Crested Ibis conservation, and to evaluate relevant influencing factors, with a view to providing recommendations for its management. The results showed that local residents strongly support the conservation of ibis and factors like education level, income, residential area, perception for ibis and prior experiences significantly affected their support for conservation. Results also indicated that the annual WTP was US$18.28 per household, and the potential value of donations is about US$2.45 million per year for Crested Ibis conservation. Regression analysis indicated that income, perception for ibis, prior experience, support for conservation and environmental attitudes had a significant effect on WTP. The comparison between the original research value of the ibis and the predicted value from the Meta-regression analysis function indicated that the benefit transfer values are able to inform policy decisions. Our results can be applied not only to the design of tailored outreach programs and management policies for the Crested Ibis, but also to facilitate conservation and management of other endangered species by encouraging decision makers to use benefit transfer models for the rapid valuation in the absence of species economic information.     

Assessing the efficiency and effectiveness of rangeland restoration in Namaqualand,South Africa

South Africa’s Succulent Karoo is home to unmatched numbers of dryland plant species. Unfortunately, decades of overstocking these rangelands with small livestock and historical ploughing for fodder have led to extensive degradation. Some areas are severely degraded, negatively affecting both agricultural livestock productivity and ecosystem health. Land degradation reduces land use options and leaves land users, and the ecosystems on which they depend, more vulnerable to environmental and economic stressors. Ecological restoration is promoted as an effective and cost-efficient option for building the resilience of local and regional ecosystems. However, dryland restoration confronts many environmental challenges that have limited its success to date. Here, we present the results of a local-scale participatory restoration trial and an assessment of the costs of regional-scale ecological restoration in the Nama Khoi area in Namaqualand, South Africa. In combination, these analyses are useful for identifying opportunities and barriers for the improved efficiency and effectiveness of dryland restoration. In Namaqualand, we find that ecological restoration is difficult and expensive. The expected impacts of climate change will only exacerbate these challenges. However, we argue that a holistic suite of land management actions that include sound management, the prevention of further degradation, and prudent investments in restoration even where costs are high is likely to be the only real option for sustaining land-based livelihoods in this region over the longer term.     

Assessing the use of artificial substrates to monitor Gambierdiscus populations in the Florida Keys

Four distinct coastal locations were sampled on a monthly basis near Long Key (Florida Keys, USA) over a 13-month period to study Gambierdiscus population dynamics on different substrates, including four macrophyte species (Dictyota spp., Halimeda spp., Laurencia spp., and Thalassia testudinum) and three artificial substrates (polyvinyl chloride (PVC) tiles, burlap, and fiberglass window screen). Cell densities of Gambierdiscus were generally lower on Dictyota versus Halimeda and Laurencia. Cell densities of Gambierdiscus were significantly correlated among macrophyte hosts in 54% of the comparisons, and between macrophyte hosts and artificial substrates in 72% of the comparisons. Predictive slopes determined from regression analyses between cell densities on artificial substrates and macrophyte hosts indicated that, on an areal basis, fewer cells were present on macrophytes versus artificial substrates (cells cm⁻²) and that slope variation (error) among the different macrophytes and sites ranged from 5% to 200%, averaging 61% overall. As the data required log-transformation prior to analyses, this level of error translates into two-orders of magnitude in range of estimation of the overall average abundance of Gambierdiscus cells on macrophytes (135 cells g⁻¹ wet weight); 20–2690 cells g⁻¹ ww. The lack of consistent correlation among Gambierdiscus cell densities on macrophytes versus artificial substrates, coupled with the high level of error associated with the predictive slope estimations, indicates that extreme caution should be taken when interpreting the data garnered from artificial substrate deployments, and that such deployments should be thoroughly vetted prior to routine use for monitoring purposes.     

Perceptual considerations in the use of colored photographic and video stimuli to study nonhuman primate behavior

The use of photographs, slides, computerized images, and video to study behavior is increasingly being employed in nonhuman primates. However, since these mediums have been designed to simulate natural coloration for normal trichromatic human vision, they can fail to reproduce color in meaningful and accurate ways for viewers with different visual systems. Given the range of color perception that exists both across and within different species, it is necessary to consider this variation in order to discern the suitability of these mediums for experimental use. Because of the high degree of visual similarity among humans, Old World monkeys, and apes, the use of photographic and video stimuli should be acceptable in terms of replicating naturalistic coloration and making noticeable color manipulations. However, among New World primates and prosimians, there exists a considerable degree of variation in color perceptual abilities depending on the species, sex, and allelic combination of the animals involved. Therefore, the use of these mediums to study behavior is problematic for these species, and should be done with caution.     

A survey of consumer attitudes to the supply and use of human hepatocytes in the United Kingdom

Human hepatocytes are the model of choice for pharmacotoxicological studies, but their acquisition is often problematic due to ethical and logistical difficulties. The UK Human Tissue Bank is a not-for-profit organisation that acquires and processes human tissue, with a specialist interest in the isolation of human hepatocytes. A recent in-house survey of the processing of liver tissue over 1 year revealed that freshly isolated hepatocytes were underutilised due to mismatched consumer demand, despite the published need for them. We present the results of a telephone survey to investigate the reasons behind this paradox. This survey highlighted some problem areas, including "out of hours" availability of cells and personnel difficulties, but overall, demonstrated the value of such a service, with numerous researchers taking advantage of available good quality human hepatocytes. Although further work is required in optimising long-term storage protocols through cryopreservation, we have demonstrated that tissue handling of this type can be successful and beneficial to the pharmaceutical and biotechnology industries.     

Assessing the effectiveness of rapamycin on angiomyolipoma in tuberous sclerosis: a two years trial

Background

Tuberous sclerosis (TS) is a rare autosomal dominant systemic disease with an estimated prevalence of 1/6000. Renal angiomyolipoma (AML) is a benign tumour with high morbidity frequently present in TS. The aim of the study was to test the effect of rapamycin in reducing the volume of AML in TS.

Methods

Twenty four-month prospective open-label, single arm, unicentre Phases II andIII study. The primary endpoint was to evaluate the effect of treatment on the reduction of at least 50% AML volume from baseline at 24 months. The secondary endpoints were: average tumour reduction, surgical complications, skin lesions and drug safety.The study population comprised 17 patients, aged >10 years who were diagnosed with TS and had ≥1 renal AML >2 cm of diameter and had a serum creatinine < 2mg/dl and urine protein/creatinine ratio < 22.6 mg/mmol. The trial was conducted at Fundació Puigvert. Rapamycin was given to achieve stable plasma levels between 4 and 8 ng/ml. AML volume was estimated using orthogonal measurements by MRI at baseline, 6, 12 and 24 months.

Results

Ten out of 17 patients were success responders for the main outcome ?58.8%, 95%CI: 32.9% to 81.6%-. After 6 months of therapy, the mean volume decrease was 55.18% (5.01 standard error (SE); p<0.001) and 66.38% (4.41 SE; p<0.001) at year 1. There was no significant decrease between year 1 and 2. According to RECIST criteria, all patients achieved a partial response at year 1 and all but two had already achieved this partial response after 6 months.The main analysis was performed according to the intention-to-treat principle analysis. Tumour volume was analyzed over time by means of mixed models for repeated measurement analysis. We used the baseline tumour volume as a covariate for the absolute change and percentage change from baseline data. The analysis was performed using SAS version 9.2 software, and the level of significance was established at 0.05 (two-sided).

Conclusions

This study show that mTOR inhibitors are a relatively safe, efficacious and less aggressive alternative than currently available options in the management of AML in TS.

Trial registration

EudraCT number: 2007-005978-30, ClinicalTrials.gov number: NCT0121712

     

Some comments on visual perception and the use of video playback in animal behavior studies

Video playback experiments are potentially powerful tools in behavioral research. A video screen mimics natural color, brightness, texture, and motion to humans (for which it was designed) because monitors stimulate human photoreceptors in approximately the same relative proportions as the stimuli that they mimic. Because most animals have vision that is very different from that of humans their cones may be stimulated very differently from ours, and an image that looks excellent to us may be unrecognizable to them, and vice versa. In this article we summarize how the simulation of a monitor works and the ways it can go wrong, using a bird and a fish model retina as examples. Finally we make some recommendations for minimizing some of these problems. Received: 10 November 1999 / Received in revised form: 22 February 2000 / Accepted: 2 March 2000     

Assessing the effectiveness of coding and non-coding regions in antisense ribosome inhibition of gene expression in Tetrahymena

In Tetrahymena thermophila, an "antisense ribosome" technology has been developed for inhibiting gene expression and generating novel mutants. Short segments of genes are inserted in antisense orientation into an rDNA vector in a region corresponding to an external loop of the folded rRNA. DNA segments derived from the 5'-ends of genes have proven most effective in reducing cognate gene expression. To investigate the efficacy of other genic regions, we generated Tetrahymena cell lines with antisense ribosome constructs containing 100-bp DNA segments derived from the 5'-ends, 3'-ends, and internal coding regions of two non-essential genes, granule lattice protein 1 and macronuclear histone H1. The 5'- and 3'-end constructs inhibited gene expression, but antisense ribosomes derived exclusively from coding regions had little effect.     

Assessing the effect of prolonged use of desloratadine on adipose Brillouin shift and composition in rats

Antihistamines, which are commonly used to treat allergic reactions, are known for their side effects, which contribute to weight gain. It is hypothesized that simultaneous Brillouin elastography and Raman spectroscopy can be used to detect changes in adipose tissue associated with a prolonged intake of desloratadine, a commonly used second generation antihistamine. White and brown adipose tissue samples were excised from adult rats following 16 weeks of daily administration of desloratadine. It was found that the prolonged intake of desloratadine leads to an increase in Brillouin shift in both adipose tissue types. Raman spectra indicate that antihistamine use reduces protein-to-lipid ratio in brown adipose tissue but not white adipose tissue, indicating the effect on adipose tissue is location-dependent.     

Assessing the impacts of biochar-blended urea on nitrogen use efficiency and soil retention in wheat production

Improving nitrogen (N) use efficiency (NUE) in crop plants is important to reduce the negative impact of excessive N on the environment. Although biochar-blended fertilizer had been increasingly tested in crop production, the fate of fertilized N in soil and plant had not been elucidated in field conditions. In this study, a novel biochar-blended urea (BU) was prepared by pelleting maize straw biochar, bentonite, sepiolite, carboxymethylcellulose sodium, and chitosan with urea (commercial urea without biochar [CU]). N fertilization in a winter wheat field was treated with BU and CU at both 265 kg N ha^?1 (HL) and 186 kg N ha^?1 (LN). Within a treatment plot, a microplot was fertilized with ¹⁵N-labeled urea at a relevant N level. We investigated the influence of fertilizer management on biomass, grain yield, bioaccumulation of nutrient, soil properties, ¹⁵N isotopic abundance, and greenhouse gas emissions. Microscopic and spectroscopic analysis showed that micro/nanonetwork of biochar could bind N to form a loss control agglomerated particle, and organo-mineral coatings on BU may protect N from quick release. Compared with CU, BU significantly increased grain yield by 13% and 38%, and grain N allocation by 19% and 55%, respectively, at HN and LN level. The total recovery of urea ¹⁵N in wheat plant (¹⁵N based NUE) was 32.8% under CU regardless of N rates but increased to 41.7% (HN rate) and 56.3% (LN rate) under BU. Whereas, the soil proportion (soil residual ¹⁵N) was 20.1% and 13.4% under CU but 32.5% and 18.8% under BU, in 0-20cm topsoil, respectively, at HN and LN rate. Compared with the CU, BU had no effect on CO₂ and CH₄ emissions but significantly reduced the total N₂O emission by 23%–28%. These important findings suggested that BU can be beneficial to uplift plant NUE to reduce reactive N loading but boost crop production.     

Smoking at the workplace: effects of genetic and environmental causal accounts on attitudes toward smoking employees and restrictive policies

People hold diverse beliefs regarding the etiologies of individual and group differences in behaviors which, in turn, might affect their attitudes and behaviors. It is important to establish how perceived etiologies of smoking might affect the effectiveness of policy initiatives and prevention efforts. The present study assessed whether exposure to genetic vs. environmental accounts for smoking affects attitudes toward (a) workplace-related smoking policies and (b) smokers at the workplace. Results indicate that exposure to a genetic explanation led to stronger objections to a smoking restrictive policy compared with a non-genetic explanation. Additionally, participants in the genetic condition were more accepting of a smoker in the workplace than those in the environmental condition. Evidently, beliefs about the etiology of smoking influence a range of attitudes related to smokers and smoking-related policies.