Le Paléolithique supérieur dans l’ouest de l’île principale du Japon

The Kinki, Chugoku and Shikoku regions are located in the western part of the Japanese mainland. This area lacks the Pleistocene volcanic soil except a part of Chugoku Mountains. For this reason, the chronology of the late Paleolithic stone industries has been mainly studied by technology and typology of the fields excavated. However, after the late 1980s, the analysis of volcanic ash that contained the Paleolithic sediments had remarkable development. As a result, the cultural layer between the distant Paleolithic sites is compared by several widespread volcanic ashes such as Aira-Tanzawa (in short AT) as key bed. In this paper, we offered chronological order of the late Paleolithic culture in these regions by comparing cultural layers on the basis of the widespread volcanic ashes, referring to typological analysis of industries. The Sétoüchi technique and Ku industry characterize the late Paleolithic culture in these regions. The Sétoüchi technique is the unique one to produce the Ku type backed knife blunting on only one side, using the particular side-blow flaking technology based on physical characteristics of sanukite stone which is a kind of andesite. However, a hypothesis named the “Sétoüchi concept” was proposed in 2001, and it has been used as a substitute of the “Sétoüchi technique” by a few Japanese researchers. So we point out the mistake of the Sétoüchi concept relying on the fact which yielded stratigraphically two different industries in the Suncheon site.     

Études du Paléolithique du Japon à partir des téphras

Many studies and discussions have been made on the problem of when the earliest human beings appeared in Japan. In general, hominid fossils in the latest Pleistocene are not preserved except for coralline limestone sequence in Ryukyu islands, but earlier Paleolithic tools were excavated from volcanic ash soil with a ¹⁴C age of about 30,000–35,000 yr. BP or younger at several archeological sites in almost all Japan. Recent studies, however, show a need for revision and refinement of these ages because calibration techniques have progressed from conventional to calendar ages and high-resolution oxygen isotope chronology has given a global standard sequence. Aïra-Tn tephra (AT), the most important time-marker of the Paleolithic age in Japan, was formerly dated at 21,000–22,000 yr ¹⁴C BP by conventional radiocarbon methods but was dated again at ca. 24,500 yr ¹⁴C BP by accelerated mass spectrometry radiocarbon methods. However, it has been further calibrated to a high-resolution calendar age of 30,000 cal yr. by varve chronology of lake sediments of Suigetsu of central Japan, well matched with combined date between oxygen isotope dates based and calibration from AMS radiocarbon dates. As the earliest Paleolithic tools in south Kanto are found in volcanic ash soil significantly below AT ash and above Sambe-Ikeda ash (SI, ca.46 ka), just above the oxygen isotopic stage 3.3, they are estimated to be dated slightly older than 40 ka. Palaeo-environment at that time is estimated mild to cool climate and relatively low sea level after the oxygen isotope stage 3.3. Sill land bridges between Japan islands and continents have not been formed at major straits. We have not yet obtained useful data for calibration older than ca. 45 ka. Also, correlation of oxygen isotopic fluctuation with the terrestrial sequences is incomplete in Stage 3.     

Les relations entre l’Extrême-Orient eurasien et le nord de l’archipel du Japon au Paléolithique

The aim of this paper is to present a review of current knowledge concerning the Paleolithic records and the related natural environmental setting in the Eurasian Far East and Hokkaido, located at the northern tip of the Japanese islands. At present, it is quite difficult to answer whether the archaic humans dispersed from Siberia and northern China across the Amur River basin and Sakhalin into Hokkaido or not, because there is no reliable evidence indicating the Lower and Middle Paleolithic in Hokkaido. We demonstrate that the Upper Paleolithic assemblages in Hokkaido can be divided into at least three phases such as the early Upper Paleolithic (EUP), the middle Upper Paleolithic (MUP), and the late Upper Paleolithic (LUP), based on a synthesis of available radiocarbon dates and the techno-typological characteristics of lithic assemblages. It is reasonable to suggest that the lithic assemblage from the Rubenosawa site, located in northern Hokkaido, and some of lithic assemblages at the transition from the Middle to Upper Paleolithic or the initial Upper Paleolithic (IUP) in Siberia share the relative similarities of techno-typological attributes in the reduction sequences, although the reliable radiocarbon dates have not been obtained from the Rubenosawa site unfortunately. Also, the emergence of microblade technology at the MUP in Hokkaido, such as represented by the microblade assemblage recovered from the Kashiwadai-1 site, central Hokkaido, indicates a close interaction between the Eurasian Far East and Hokkaido. As a result, the comparison of archaeological evidence in these regions provides us with a suggestion that the appearance and development of the Upper Paleolithic assemblages in Hokkaido were sometimes associated with the human dispersions and the mutual contacts crossing between the Eurasian Far East and Hokkaido.     

Chronologie du Paléolithique supérieur dans le Nord-Est de la principale île du Japon

Palaeolithic archaeology in Tohoku region has long been discussed on constructing chronology, however it is difficult to build reliable chronological order because of poor stratigraphic excavations. In recent radiocarbon dating has advanced. In this paper I discuss the relation between chronology and radiocarbon dating in Tohoku region. At first, I categorize the Palaeolithic industries and establish the chronology by analyzing tool typology, lithic technology, and stratigraphic data. I correlate it with radiocarbon data from sites in Tohoku region. The result of analysis shows that Upper Palaeolithic industries are divided into 18 categories and 8 periods on chronology. The calibration curve IntCal 13 indicated that oldest Early Upper Palaeolithic site appeared around 37,000 cal BP, and late Upper Palaeolithic started about 27,000 cal BP. The pottery first appeared as far back as around 16,000 cal BP. Now we do not have enough radiocarbon data, so we have to gather and examine more ¹⁴C data.     

La technique de débitage au Paléolithique supérieur de l’archipel du Japon

The representative debitage technique is the one of the culture of knife-to-back in the name of the superior Paleolithic of Japan. She/it can be he divided in two, the one of the first half and the one of the second half. The first corresponds at the time of apparition, either to the stage of launching of the technique of debitage laminaire whose debitage didn’t provide elaborate blades being little successive. As for the stage of fortifying of the debitage laminaire, the industries lithic to knife-to-back of the Sugikubo type developed themselves in the oriental Honshû. With regard to the region of Kantô to the second half of the first where the knife-to-back of Moro type mingled equally with those while shaping on the blade. To the recent stage of development, one can note the industry lithic to knife-to-back of Moro type is based on the technical very blady in the western Japan. Succeeding in the second half of the superior Paleolithic that the technique of debitage of Sétoüchi developed itself in this part whose debitage is characterized by the strut oblong in wing, are the transverse blades These gotten supports used especially for making the knife-to-back of Koü type while spilling country-wide. To the second recent half, the technical blade of Sunagawa type took place in all regions of Japan except the inshore regions of the Interior Sea of Séto and the region of Kinki (Kyoto-Osaka).     

Le Paléolithique des îles du Sud-Ouest du Japon

There are two lithic industries in the beginning of the Upper Paleolithic including the vestiges that have been discovered in the islands of Oshumi, close to the island of Kyushû. This lithic industry is characterized by the presence of axes with partially polish cutting, denticulate, hammers and millestones that are common in western Japan. It is characterized by numerous lithic instruments for the treatment of the plant food. The discovered vestiges of which one found the pebbles cluster inside pitfalls that are the oldest on the archipelago of Japan. According to these particularities of the lithic industry and vestiges, it is likely that this human group is semi-settled. And this human group of the beginning Upper Paleolithic was identical typologically and technically to the human group of the island of Kyushû. Therefore, it is possible that they came down from the southbound Kyushû Island, to the concerned islands. As for the islands of Amami, we investigated sites, nevertheless all that have been unearthed, in small extents provided a small quantity of the archaeological material. Indeed, one could not seize very well retails until now. There is a mixture of various, non-resolute opinions. The islands of Okinawa and those of Sakishima in southern extremity of the Japanese territory provided humans rests of the Upper Paleolithic, nevertheless no lithic industry of the same time have been found. Thereafter of the situation, the origins of the culture and the technique concerned the human rests remain unclear.     

Le mammouth dans l’art paléolithique

The mammoth, an emblematic animal of the Prehistory, possesses an important place in the depictions made by prehistoric artists, both in parietal art (cave art) and in mobile art. Its image is known from the Aurignacian, at the beginning of the Upper Palaeolithic, until the end of the Last Ice Age, the Magdalenian. However, its geographical and chronological distribution is dissimilar. Mammoth depictions are generally more frequent during the Aurignacian where this animal is found engraved and painted in the Chauvet cave for example and carved from ivory in several cave sites of the Swabian Jura. The Magdalenian cave of Rouffignac and its 160 representations constitute a notable exception. From a formal point of view, the representations of mammoth are elaborated in a rather constant way, like the characteristic cephalic contour and the typical back of the animal, at least as it could be seen in nature. The representations are often even limited to a cursive line with a double curvature that expresses the pachyderm. On the other hand some drawings show intimate details. Sometimes the tusks of the mammoths are not indicated, but certain stylistic features, such as the ventral arch, are relatively reliable chronological markers. Finally, one cannot ignore the ethological or seasonal expressions that sometimes link the mammoths to each other, in a row or in confrontation. This animal obviously inspired the artists of the prehistory who created various portraits of the mammoth.     

L’étude des pointes foliacées dans l’archipel du Japon

Approximately 10,000 Paleolithic sites have been approved in Japan. Transitions of the hunting weapons that represent stone implements are as follows.1. Stone implements that represent the Trapezoids and the Proto knives appeared approximately 32,000 years ago.2. Stone implements that represent bilaterally retouched knives of willow-leaf sharp and bilaterally retouched transversal knives developed approximately 29,000 years ago.3. Approximately 28,000 years ago, after Aira-Tn volcanic ash fell down, the Kakusuijo-sekki appeared. This Kakusuijo-sekki got involved in the appearance of Bifacial points.4. As Bifacial points developed, Backed Blades also gradually declined approximately 20,000 years ago.5. Consequently, this led to the development of Micro-blades, which went well with Bifacial points approximately 19,000 years ago.6. Although Micro-blades became extinct under the influence of the appearance of Tanged points, Arrow-heads, and Potteries approximately 16,000 years ago, Bifacial points kept being produced.Approximately 18,000 years ago, bifacial points which were produced symmetrically and bifacially were widely developed in Japan; however, the stones, the size of the material by exfoliate technique, and the processing method were different from what was expected.Such transitions have been investigated in each region, which helps us understand that stone implements in the Paleolithic Era were found at multiple stratified sites in the thickly sedimented Pleistocene tephra at the Sagamino Terra, Kanagawa Prefecture.     

Armes de chasse dans l’Épipaléolithique du Caucase du Nord

The article is devoted to the traceological study of points and geometric microliths that are characteristic of the Epipaleolithic sites of the northwestern Caucasus and the Elbrus region. The regularities between the type of stone tools and their functional use are analyzed. Composite hunting weapons were effectively used in hunting a variety of ungulate herd animals. The composition of faunal assemblages largely depended of climatic and landscape conditions of the sites in different periods of the Late Glacial period: from the Oldest Dryas to the Pleistocene–Holocene transition. The proximity of lithic industries within a vast region in the North Caucasus, similar shapes of projectiles and lithic inserts into composite hunting weapons could be associated with active human movements, which are confirmed by the transportation of obsidian from the Elbrus region to the northwestern Caucasus and the transportation of high-quality flint from the west to the Elbrus region in the north-central Caucasus.     

Le Paléolithique de l’île de Kyûshû

The Upper Paleolithic of this region divides in five chronological stages. The first stage is an oldest period on the archipelago of Japan. The lithic industry of the stage is composed by the denticulate, the pointed scraper, the pick and the bifacial tool. The second half of the first stage is characterized the emergence of Kiridashi type backed knife and trapezoidal backed knife. The debitage (flaking) of the first half and the second half is non-blade technique. The second stage is characterized newly by the apparition of willow leaf type backed knife and partial retouching backed knife. The knife-to-back of the type of Kiridashi and the trapezoidal knife-to-back exist again while constantly joining the willow leaf type backed knife and the partial retouching baked knife. The blade debitage was present, principally the one of various flakes. As for the second half of the second stage, the willow leaf type backed knife and the partial retouching backed knife are represented mainly, besides the Kiridashi type baked knife and the trapezoidal backed knife mingled with this typological composition. The debitage was founded on the blade technique. The point on flake (tanged flake point) and the trihedral faced point appeared at the third stage that is a big instrument of hunt. It is likely that the behavior for hunting the big game would have been brought while passing by the land-bridge toward the Kyushu Island during the Maximum-Coldness of the last glaciation. Regarding the fourth stage, the point on flake disappeared, and the industry is essentially composed of trihedral faced point and the spear type point. The flat trihedral faced point and spear type point appeared, and the trihedral faced point appeared on the western part of South-Kyûshû and the part of northern Kyûshû. The culture of the trihedral faced point tips at the third stage on the Kyûshû Island that prolongs until the concerned stage. The fifth stage is the end of the Upper Paleolithic that is characterized by the Microlithic Culture. It is characterized by the miniaturize of the backed knife. At the end, the microlithisation resuscitates at the end of the Upper Paleolithic.     

Place de l’imagerie dans l’évaluation de l’efficacité des traitements dans le cancer du sein

This paper describes, from the current literature, the role of various imaging methods to assess the response to therapy in breast cancer. Two different clinical situations are considered: neoadjuvant chemotherapy of locally advanced breast cancer and the metastastic breast cancer. Significant clinical data are available for three criteria: the volume of the tumour, the uptake of fluorodeoxyglucose using PET and the perfusion of the tumor evaluated either by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) or by PET using ¹⁵O water. ¹⁸F FDG PET allows prediction of the response after one or two cycles of neoadjuvant chemotherapy. New approaches will offer opportunities to refine the role of imaging in monitoring the response to chemotherapy. PET using thymidine as biomarker is promising in assessing the tissular proliferation. Estrogen analogs could be used to predict hormonally responsive breast cancer. Many other approaches, although less developed, might offer new insights in the response to therapy of breast cancer like magnetic resonance spectroscopy or optical imaging of hemoglobin oxygenation. Imaging also offers potential of monitoring the down-regulation of specialized receptors of the cell membrane in response to treatment: the most studied receptor in preclinical model has been the human epidermal growth factor receptor type 2 (HER2). Integrin, a family of cell adhesion receptor, is also an important target for imaging. Apoptosis, multidrug resistance and hypoxia can also be studied using appropriate biomarkers. To allow reliable multicenter trials of new drugs, these different imaging approaches still require an improved standardization of image acquisition and processing.     

Découverte des sites du Paléolithique inférieur au Nord de l’Arménie

For a long time, the scientific community assumed that the Acheulean culture was expressed on the territory of the Armenian Plateau as well as in the neighboring regions of the Caucasus only by its late phase; therefore, it appeared in the second half of the Middle Pleistocene. In recent years, the Armenian-Russian mission has discovered and studied much older Acheulean industries sites, located in northern Armenia (the Lori intermountain Depression). These industries, represented by archaic type tools (large hand axes, picks, choppers, chisel-like tools, scrapers, points, etc.), are discovered in three deposits of origin of proluvial genesis. In the Karakhach site, this type of industry is deposited in the lower levels of volcanic tuff and below; the U/Pb study of this level of tuff proposes a series of dates, assigned to the time interval between 1.944 + 0.046 and 1.75 + 0.02 Ma. The paleomagnetic study demonstrated the inverse polarity on the tuff and the normal polarity of the underlying deposits; in correlation with other dating, this fact allows to attribute the Acheulean layers of the site of Karakhatch to the Lower Pleistocene, in particular to the Oldoway episode and to the Upper Matuyama time period. The estimated age and the techno-morphological characteristics of the tools indicate the Lower Acheulean period. The dating of the Muradovo site does not seem possible, however its very old industries and the archaeological layers, where they were discovered, find equivalents in the layered layer, surmounted by tuffs, of the Karakhatch site. The Kutran I site presented a paleosol sequence with similar Acheulean tools (hand axes, picks, choppers, etc.). Its oldest layer is older than 1.5 Ma, the upper layer is attributed to the early Middle Pleistocene; this fact means that it is possible to speak of the Lower Acheulean and of its transition to the Middle Acheulean period. The specific character and the age of the Lower Acheulean of Armenia admit that it could have formed independently of the Lower Acheulean of Africa, whose estimated age does not rise before 1.76 Ma. It should also be noted that on the neighboring territory of Georgia about the same time when appeared the Acheulean culture in Armenia, the Oldowan Dmanisi site already existed.     

évaluation des pratiques professionnelles dans le cadre de l’accréditation des établissements psychiatriques

As regards evaluation of professionnal practices (EPP), Formep’s has decided to stay in the limits of psychiatric institutions, for reason of experience. Every medical doctor working in these institutions is concerned by evaluation, but also institutions in the specific framework of V2 44, 45 and 46 references. The EPP is multidisciplinary and involves everybody who takes part of patient caring. Formep’s is adviser, training agent, and partner. Follow-up takes place both on-site and off-site all along the EPP, by a team including psychiatrists, medical practitioners, quality and risk management engineers. They are all experienced to work in psychiatric institutions. Formep’s program includes preliminary and definitive choice of themes, putting methology is place, work of teams, initial analysis of results and deviations, further work of teams, final analysis, which purpose is to improve practices and therefore medical benefit.     

Les problèmes géologiques et typologiques des sites paléolithiques dans le Nord-Est du Japon

The northeastern area of Honshu is composed of six departments: Aomori, Iwate, Akita, Miyagi, Yamagata and Fukushima. The study of Paleolithic began in 1927 and has given place to the discovery of the site of Hanaizumi. Subsequently, one pushed the research below on land and the discovery of the first paleolithic site in Iwajyuku happened in 1946. Then, H. Nakagawa took back a success of survey of the geomorphological processes and the ordering of the fluviatile terraces with some layers from the volcano-sedimentary deposit of the Pleistocene in the basin of Kitakami and the one of Mabechi. Therefore, we understood that the archaeological levels of the region contain several sedimentary deposits volcano of quaternary origin from the Mounts Öu. In the basin of Kitakami, one noted the deposit of fall pyroclastic of Aiçra (AT) above the layer of the local volcanic ash from Kurosawajiri. Especially, it is one key of an important layer, the last horizon located under AT and above the tephra of Daïfudô from the local volcano, the pyroclastic stream of Towada and the involution of the layer of the volcanic ash from Kurosawajiri. More than 610 paleolithic sites has been counted in the Northeast.     

Études géoarchéologiques pluridisciplinaires des sites du Paléolithique moyen de la Plaine Russe

The paper presents some preliminary results of comprehensive geoarcheological researches of Middle Paleolithic open-air sites, situated at the different regions of the Russian plain, which had been continued after a short pause. Our issue focused on the main key-sites from Upper Desna (Khotylevo I and Betovo) to the Lower Volga (Suhaya Mechetka), Northern Azovian sea-coast (Rojok I and Nosovo I), Middle (Shlyah) and Lower (Birjuchaya Balka 2) Don regions. Those studies conducted at a new methodological level during the last five years have allowed us to obtain new information on the chronological and lithologic-stratigraphic positions of sites, the degree of preservation of Cultural layers and the peculiar features of those assemblages. A table with series of uncalibrated radiocarbon dates demonstrates the variants of correlation of complexes in the interval from the second half of the middle (MIS-3) to the beginning of the later (MIS-2) part of the Valdaï period.     

Effets de l’Oxygenation du Milieu d’Incubation des Cotyledons de Ricin sur les Flux de Protons et sur l’Absorption du Saccharose

Some of the effects of oxygen concentration in the external medium bathing castor bean cotyledons were investigated. At 700 μM O₂, the sucrose-dependent proton influx was dependent on external pH while sucrose influx was independent of pH between 4,5 and 6; proton influx and sucrose influx were both dependent on external sucrose concentration; both were saturated above 50 mM sucrose. The stoichiometry H+/S decreased with increasing pH and sucrose concentration. These data were consistent with the results obtained in stirred or aerated external medium. Oxygen consumption, acidification of the medium, sucrose-dependent proton influx and sucrose uptake increased with increasing oxygen concentration up to 700 μM where saturation was reached. Bubbling with air (O₂, 160 μM) resulted in the same increase despite lower oxygen concentration. It is suggested that not only O₂ concentration but also CO₂ concentration act on O₂ consumption, and proton and sucrose fluxes.

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Le Paléolithique supérieur dans la péninsule coréenne et l’archipel du Japon

There is one decisive gate between the Asian continent and the archipelago of Japan which is the strait of Tsushima that exists between the Korean peninsula and the archipelago. The strait is very narrow; however, the depth is relatively deep. If the sea level did not fall down to at least 130 meters below the present level, the terrestrial bridge would not be formed there. We know the former case concerning the first human population of which crossed this maritime gate of human groups 50,000 years ago. One supposes that the men did not have any means to cross there without the terrestrial bridge previous to 50,000 years. According to the studies of the abyssal drills of the Sea of Japan that one noted several lowering of the sea level according to the marine isotopic stages (MIS): 2, 6, 10, 12, 16, 18 and 20. With regard to the marine isotopic stage 2 that correspond to the Maximum-coldness of the last glacial when the sea dropped in below 125 meters in relation to the present level. According to study of the seismic stratigraphy and according to the obtained ages of seabed sediments by the method of carbon 14 that one concluded the concerned strait remained always like a marine channel and narrow during the last glacial (Park et al., 2000). We notice the typological common points between the lithic industry of the Korean peninsula and the one of the Kyushu island during the marine isotopic stage 2 (MIS-2) which are the tanged point (flake point), the bifacial point to triangular section (point to three retouched faces), etc. However, there are some differences in the composition of tools and the fabrication technique. Regarding the cultural origin and the big human migration, we cannot prove them for now. Such situation showed that some obstacles existed between such two regions. There are no common features on the flaking technique and the typology before 50,000 years in these two regions since we do not have any affirmative overdraft.     

L’outillage lithique taillé dans le grand gisement paléolithique de Mitoc-Malu Galben

In this Palaeolithic site, at the moment the largest habitation undergoing investigations in Europe, several archaeological layers were discovered: Lower Aurignacian I, Aurignacian I, II, III and Upper Aurignacian III, Gravettian I, II, III, IV and Dispersed Gravettian. The systematic archaeological investigations were conducted between 1978 and 2017 and covered a surface of more than 900 square meters, reaching a depth of approximately 14 m. Stone artefacts worked in non-local raw materials were identified, as well as a survival of Aurignacian elements within the Gravettian medium, as suggested by the presence of carenated pieces, scarpers, etc.