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1.
Jesús Fernndez Carlos Lpez-Fanjul 《Evolution; international journal of organic evolution》1997,51(3):856-864
Spontaneous mutations were allowed to accumulate for 104–161 generations in 113–176 inbred lines, independently maintained by a single brother-sister mating per generation, all of them derived from a completely homozygous population of Drosophila melanogaster. In each of two to three consecutive generations, all lines were scored for fecundity, egg-to-pupa and pupa-to-adult viabilities, both in the standard laboratory culture medium (ST) and in three harsh media differing from the former by a single factor: higher temperature (HT), higher NaCl concentration (HSC), or a much reduced concentration of nutrients (D). Relative to the standard medium, productivity (fecundity × viability) decreased by 25% (HT), 66% (HSC), and 80% (D). In each medium, mutational variances of those traits and mutational covariances between all possible pairs were calculated from the between-line divergence (codivergence). Mutational correlations between character states in different media were also obtained. Because we used inbred lines, those estimates were mainly due to the accumulation of mildly detrimental mutations, deleterious mutations of large effect being underrepresented. For all traits, mutational heritabilities ranged from 1.41 × 10–4 to 11.24 × 10–4, and did not increase with intensified environmental harshness. Mutational correlations between character states in different media were usually not large (average absolute value 0.31), reflecting a high degree of environmental specificity of the mutations involved. In our results, mutations quasi-neutral in ST conditions and mildly detrimental in more stressful media were not, as a class, important. Mutational correlations between fecundity and egg-to-pupa viability were small and positive in all media. Those involving pupa-to-adult viability were positive in HT, nonsignificant in HSC, and negative in ST and D, showing how the genetic covariance structure of quantitative traits in populations may change in variable environments. 相似文献
2.
The Effects of Spontaneous Mutation on Quantitative Traits. I. Variances and Covariances of Life History Traits 总被引:9,自引:4,他引:5
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D. Houle K. A. Hughes D. K. Hoffmaster J. Ihara S. Assimacopoulos D. Canada B. Charlesworth 《Genetics》1994,138(3):773-785
We have accumulated spontaneous mutations in the absence of natural selection in Drosophila melanogaster by backcrossing 200 heterozygous replicates of a single high fitness second chromosome to a balancer stock for 44 generations. At generations 33 and 44 of accumulation, we extracted samples of chromosomes and assayed their homozygous performance for female fecundity early and late in adult life, male and female longevity, male mating ability early and late in adult life, productivity (a measure of fecundity times viability) and body weight. The variance among lines increased significantly for all traits except male mating ability and weight. The rate of increase in variance was similar to that found in previous studies of egg-to-adult viability, when calculated relative to trait means. The mutational correlations among traits were all strongly positive. Many correlations were significantly different from 0, while none was significantly different from 1. These data suggest that the mutation-accumulation hypothesis is not a sufficient explanation for the evolution of senescence in D. melanogaster. Mutation-selection balance does seem adequate to explain a substantial proportion of the additive genetic variance for fecundity and longevity. 相似文献
3.
Punya Nachappa David C. Margolies James R. Nechols Theodore J. Morgan 《Evolutionary ecology》2010,24(4):631-655
In nature, where predators must often track dynamic and dispersed prey populations, predator consumption rate, conversion
efficiency, dispersal, and prey finding are likely to be important links between foraging and predator–prey population dynamics.
Small differences in predator foraging caused by variation in any of the abovementioned traits might lead to significant differences
in predator success as well as population dynamics. We used artificial selection to create lines of the predatory mite, Phytoseiulus persimilis in order to determine the potential for or constraints on the evolution of predator foraging behaviors. All four foraging
traits demonstrated considerable phenotypic variation. They also exhibited significant realized heritabilities after artificial
selection, except that prey finding did not respond to downward selection. Lines that responded to selection did so rapidly,
and high-consumption, high-conversion efficiency, and high- and low-dispersal were stable for at least four generations after
artificial selection was relaxed. There were some indirect responses to selection among the foraging traits. For example,
there was positive correlation between consumption and dispersal. However, none of the correlated responses were of the magnitude
of the direct responses we measured on the same trait. We also observed some correlations between foraging traits and life-history
traits such as low-consumption and development time (negative), high-consumption and fecundity (positive), and high-conversion
efficiency and fecundity (positive), but these were more likely to represent non-genetic constraints. Intrinsic rates of increase
in low-consumption and low-conversion efficiency lines were lower than in their respective high lines and the unselected control,
whereas rates of increase in dispersal and olfactory response lines did not differ from the unselected control. Thus, traits
that make up foraging share partially overlapping genetic architectures with highly heritable phenotypic components, suggesting
that each foraging trait will be able to respond rapidly to changes in the density and distribution of resources. 相似文献
4.
The homozygous effects of ethylmethane sulfonate (EMS)-induced mutations in Caenorhabditis elegans are compared across life-history traits. Mutagenesis has a greater effect on early than late reproductive output, since EMS-induced mutations tend to cause delayed reproduction. Mutagenesis changes the mean and variance of longevity much less than reproductive output traits. Mutations that increase total or early productivity are not detected, but the net effect of mutations is to increase and decrease late productivity to approximately equal extents. Although most mutations decrease longevity, a mutant line with increased longevity was found. A flattening of mortality curves with age is noted, particularly in EMS lines. We infer that less than one-tenth of mutations that have fitness effects in natural conditions are detected in the laboratory, and such mutations have moderately large effects ( approximately 20% of the mean). Mutational correlations for life-history traits are strong and positive. Correlations between early or late productivity and longevity are of similar magnitude. We develop a maximum-likelihood procedure to infer bivariate distributions of mutation effects. We show that strong mutation-induced genetic correlations do not necessarily imply strong directional correlations between mutational effects, since correlation is also generated by lines carrying different numbers of mutations. 相似文献
5.
In this article we investigate the direct and correlated responses to selection for developmental time in order to discern differences between lines in several preadult and adult life history traits of Acanthoscelides obtectus (Coleoptera, Bruchidae). Selection for fast development was about five times as effective as selection for slow development, as judged by realized heritabilities. The correlated responses on the following life‐history traits were studied: egg size, hatching success, embryonic developmental time, egg‐to‐adult viability, body weight, first day of egg laying, total fecundity, and longevity. Analyses of the terminal generation of selection showed that all life history traits examined, except for hatching success, were affected by selection. The findings suggest that body weight, total fecundity, and longevity traded off to preadult developmental time. Unlike the adult traits, none of the preadult traits showed negative correlations with developmental time. We also present data concerning the underlying genetic basis that produces changes in preadult developmental time, body weight, and egg‐to‐adult viability in the lines selected for fast and slow preadult developmental time. Additive‐dominance genetic architecture for both preadult developmental time and body weight was found. In addition, it appears that the responses to selection for preadult developmental time involved between 10 and 28 loci, which were correlated with at least one to four genes for body weight. Epistasis makes a significant contribution to genetic divergence between fast and slow selected lines only with respect to preadult viability. The observed levels of dominance and epistasis underscore the important role of nonadditive genetic effects to the adaptive diversifications of bean weevil populations. 相似文献
6.
Sexual selection when the female directly benefits 总被引:9,自引:0,他引:9
TREVOR PRICE DOLPH SCHLUTER NANCY E. HECKMAN 《Biological journal of the Linnean Society. Linnean Society of London》1993,48(3):187-211
Why do females of many species mate with males on the basis of traits apparently detrimental to male survival? The answer may lie in the fact that these male traits are correlated with male condition. We consider the argument that high male condition directly benefits female fecundity and/or viability (e.g. through lower transmission of parasites, improved control of resources, or better paternal care). Using a quantitative genetic model we show how female preferences for male traits that indicate condition can evolve, even if the male traits themselves have deleterious effects on both the male and the female's fecundity. So-called ‘arbitrary preferences’ can spread in this way because male traits subject to sexual selection are often under additional selection to become correlated with condition. At equilibrium the positive effects of male condition on a female's fecundity and the negative effects of the male trait on her fecundity are balanced and the female preference is under stabilizing selection. The male trait will often be correlated with viability, but not with fecundity, even though the preference evolved as a result of differences in male fecundity. The mean fecundity of females is not maximized, and can steadily decline as the male trait and female preference evolve. If the male trait has no direct deleterious effects on female fecundity, as may happen in species with no paternal care, female preferences are under continuous directional selection to increase. 相似文献
7.
We examined the influence of parental age on life history traits of their offspring in the lines of bean weevil that have
evolved different rates of senescence. Measurements included preadult traits (egg size, embryonic developmental time, total
preadult developmental time, preadult viability) and adult traits (body weight, total realized fecundity of females, first
day of egg laying, early fecundity, late fecundity and longevity). The negative parental age effects were observed for all
traits except for the early and total realized fecundity. We did not detect statistically significant line×parental age interactions
for either preadult- or adult-survival, so offspring survival did not change with parental age after selection for early vs.
late reproduction. It seems that selection acting on the quality of offspring produced by parents of different ages has not
been responsible for the evolution of senescence in bean weevil.
This revised version was published online in August 2006 with corrections to the Cover Date. 相似文献
8.
P element mutagenesis was used to construct 94 third chromosome lines of Drosophila melanogaster which contained on average 3.1 stable P element inserts, in an inbred host strain background previously free of P elements. The homozygous and heterozygous effects of the inserts on viability and abdominal and sternopleural bristle number were ascertained by comparing the chromosome lines with inserts to insert-free control lines of the inbred host strain. P elements reduced average homozygous viability by 12.2% per insert and average heterozygous viability by 5.5% per insert, and induced recessive lethal mutations at a rate of 3.8% per insert. Mutational variation for the bristle traits averaged over both sexes was 0.03Ve per homozygous P insert and 0.003Ve per heterozygous P insert, where Ve is the environmental variance. Mutational variation was greater for the sexes considered separately because inserts had large pleiotropic effects on sex dimorphism of bristle characters. The distributions of homozygous effects of inserts on the bristle traits were asymmetrical, with the largest effects in the direction of reducing bristle number; and highly leptokurtic, with most of the increase in variance contributed by a few lines with large effects. The inserts had partially recessive effects on the bristle traits. Insert lines with extreme bristle effects had on average greatly reduced viability. 相似文献
9.
Evolution of increased competitiveness in cows trades off with reduced milk yield,fertility and more masculine morphology
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Cristina Sartori Roberto Mantovani 《Evolution; international journal of organic evolution》2015,69(8):2235-2245
In some species females compete for food, foraging territories, mating, and nesting sites. Competing females can exhibit morphological, physiological, and behavioral adaptations typical of males, which are commonly considered as secondary sexual traits. Competition and the development of traits increasing competitiveness require much energy and may exert adverse effects on fecundity and survival. From an evolutionary perspective, positive selection for increased competitiveness would then result in evolution of reduced values for traits related to fitness such as fecundity and survival. There is recent evidence for such evolutionary trade‐offs involving male competition, but no study has considered competing females so far. Using data from competitions for dominance in cows (Bos taurus), we found negative genetic correlations between traits providing success in competition, that is, fighting ability and fitness traits related to milk production and with fertility (the inverse of parity‐conception interval). Fighting ability also showed low but positive genetic correlations with “masculine” morphological traits, and negative correlations with “feminine” traits. A genetic change in traits over time has occurred due to selection on competitiveness, corresponding to an evolutionary process of “masculinization” counteracting the official selection for milk yield. Similar evolutionary trade‐off between success in competition and fitness components may be present in various species experiencing female competition. 相似文献
10.
ALEJANDRA C. SCANNAPIECO PABLO SAMBUCETTI FABIAN M. NORRY 《Biological journal of the Linnean Society. Linnean Society of London》2009,97(4):738-748
The possible associations between longevity, early fecundity, and stress-resistance traits were explored using artificial selection on longevity in a laboratory population of Drosophila buzzatii . Three replicated lines were selected for increased lifespan (L lines) and compared with the respective unselected controls (C lines) after the 14th generation of selection. Mean longevity exhibited a significant response to selection. The baseline mortality tended to decrease in the L lines and a negative correlated response to longevity selection was found for early fecundity. Egg-to-adult developmental time increased in L lines. Longevity selection increased stress resistance for both high and low temperatures, as measured by heat knockdown resistance and chill-coma recovery. Starvation resistance also tended to be higher in L than in C lines. The results obtained are consistent with the hypothesis of trade-offs between longevity and early fecundity, and also suggest a trade-off association between adult longevity and developmental time. Correlated selection responses were generally consistent with correlations among the traits previously inferred from altitudinal clines for longevity and stress-resistance phenotypes. © 2009 The Linnean Society of London, Biological Journal of the Linnean Society , 2009, 97 , 738–748. 相似文献
11.
If genetic variation for fitness traits in natural populations ("standing" variation) is maintained by recurrent mutation, then quantitative-genetic properties of standing variation should resemble those of newly arisen mutations. One well-known property of standing variation for fitness traits is inbreeding depression, with its converse of heterosis or hybrid vigor. We measured heterosis for three fitness traits, pre-adult viability, female fecundity, and male fertility, among a set of inbred Drosophilia melanogaster lines recently derived from the wild, and also among a set of lines that had been allowed to accumulate spontaneous mutations for over 200 generations. The inbred lines but not the mutation-accumulation (MA) lines showed heterosis for pre-adult viability. Both sets of lines showed heterosis for female fecundity, but heterosis for male fertility was weak or absent. Crosses among a subset of the MA lines showed that they were strongly differentiated for male fertility, with the differences inherited in autosomal fashion; the absence of heterosis for male fertility among the MA lines was therefore not caused by an absence of mutations affecting this trait. Crosses among the inbred lines also gave some, albeit equivocal, evidence for male fertility variation. The contrast between the results for female fecundity and those for male fertility suggests that mutations affecting different fitness traits may differ in their average dominance properties, and that such differences may be reflected in properties of standing variation. The strong differentiation among the MA lines in male fertility further suggests that mutations affecting this trait occur at a high rate. 相似文献
12.
The evolution of sexual dimorphism will depend on how sexual, fecundity and viability selection act within each sex, with the different forms of selection potentially operating in opposing directions. We examined selection in the dioecious plant Silene latifolia using planted arrays of selection lines that differed in flower size (small vs. large). In this species, a flower size/number trade-off exists within each sex, and males produce smaller and more numerous flowers than females. Moreover, floral traits are genetically correlated with leaf physiology. Sexual selection favoring males in the small-flower line occurred via greater overlap in the timing of flower output between males from this line and females. Fecundity selection favored males with high flower production, as siring success was proportionate to pollen production. Viability selection opposed sexual selection, favoring males from the large-flower line. In females, fecundity and viability selection operated in the same direction, favoring those from the large-flower line via greater seed production and survival. These results concur with the pattern of floral sexual dimorphism. Together with previous results they suggest that the outcome of the different forms of selection will be environmentally dependent, and therefore help to explain variation among populations in sexually dimorphic traits. 相似文献
13.
Hybrid Dysgenesis-Induced Quantitative Variation on the X Chromosome of Drosophila Melanogaster 总被引:5,自引:5,他引:0
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To determine the ability of the P-M hybrid dysgenesis system of Drosophila melanogaster to generate mutations affecting quantitative traits, X chromosome lines were constructed in which replicates of isogenic M and P strain X chromosomes were exposed to a dysgenic cross, a nondysgenic cross, or a control cross, and recovered in common autosomal backgrounds. Mutational heritabilities of abdominal and sternopleural bristle score were in general exceptionally high-of the same magnitude as heritabilities of these traits in natural populations. P strain chromosomes were eight times more mutable than M strain chromosomes, and dysgenic crosses three times more effective than nondysgenic crosses in inducing polygenic variation. However, mutational heritabilities of the bristle traits were appreciable for P strain chromosomes passed through one nondysgenic cross, and for M strain chromosomes backcrossed for seven generations to inbred P strain females, a result consistent with previous observations on mutations affecting quantitative traits arising from nondysgenic crosses. The new variation resulting from one generation of mutagenesis was caused by a few lines with large effects on bristle score, and all mutations reduced bristle number. 相似文献
14.
C. R. Freeman‐Gallant R. L. Schneider C. C. Taff P. O. Dunn L. A. Whittingham 《Journal of evolutionary biology》2014,27(5):982-991
Females often possess ornaments that appear smaller and duller than homologous traits in males. These ornaments may arise as nonfunctional by‐products of sexual selection in males and cause negative viability or fecundity selection in females in proportion to the cost of their production and maintenance. Alternatively, female ornaments may function as signals of quality that are maintained by sexual or social selection. In a 4‐year study of 83 female common yellowthroats (Geothlypis trichas) and their 222 young, we found strong viability and fecundity selection on the yellow bib, a carotenoid‐based plumage ornament that is a target of sexual selection in males. Females with larger bibs were older, larger and more fecund than females with smaller bibs. However, bib size positively covaried with bib total brightness and carotenoid chroma, aspects of bib coloration that were under negative viability and fecundity selection. Females with more colourful bibs laid fewer eggs in their first clutch, were more likely to suffer total brood loss due to predation and were less likely to return to the study area. Selection against bib coloration limits the value of bib size as a quality indicator in females and may constrain the elaboration of bib attributes in males. 相似文献
15.
Spontaneous mutations were allowed to accumulate over 209 generations in more than 100 lines, all of them independently derived from a completely homozygous population of Drosophila melanogaster and subsequently maintained under strong inbreeding (equivalent to full-sib mating). Traits scored were: abdominal (AB) and sternopleural (ST) bristle number, wing length (WL) and egg-to-adult viability (V). On two occasions--early (generations 93-122) and late (generations 169-209)--ANOVA estimates of the mutational variance and the mutational line x generation interaction variance were obtained. Mutational heritabilities of morphological traits ranged from 2 x 10(-4) to 2 x 10(-3) and the mutational coefficient of variation of viability was 0.01. For AB, WL and V, temporal uniformity of the mutational variance was observed. However, a fluctuation of the mutational heritability of ST was detected and could be ascribed to random genotype x environment interaction. 相似文献
16.
G. Dwyer 《Journal of evolutionary biology》2015,28(10):1828-1839
Investment in host defences against pathogens may lead to trade‐offs with host fecundity. When such trade‐offs arise from genetic correlations, rates of phenotypic change by natural selection may be affected. However, genetic correlations between host survival and fecundity are rarely quantified. To understand trade‐offs between immune responses to baculovirus exposure and fecundity in the gypsy moth (Lymantria dispar), we estimated genetic correlations between survival probability and traits related to fecundity, such as pupal weight. In addition, we tested whether different virus isolates have different effects on male and female pupal weight. To estimate genetic correlations, we exposed individuals of known relatedness to a single baculovirus isolate. To then evaluate the effect of virus isolate on pupal weight, we exposed a single gypsy moth strain to 16 baculovirus isolates. We found a negative genetic correlation between survival and pupal weight. In addition, virus exposure caused late‐pupating females to be identical in weight to males, whereas unexposed females were 2–3 times as large as unexposed males. Finally, we found that female pupal weight is a quadratic function of host mortality across virus isolates, which is likely due to trade‐offs and compensatory growth processes acting at high and low mortality levels, respectively. Overall, our results suggest that fecundity costs may strongly affect the response to selection for disease resistance. In nature, baculoviruses contribute to the regulation of gypsy moth outbreaks, as pathogens often do in forest‐defoliating insects. We therefore argue that trade‐offs between host life‐history traits may help explain outbreak dynamics. 相似文献
17.
Age-specific effects of spontaneous mutations on mortality rates in Drosophila are inferred from three large demographic experiments. Data were collected from inbred lines that were allowed to accumulate spontaneous mutations for 10, 19, and 47 generations. Estimates of age-specific mutational variance for mortality were based on data from all three experiments, totalling approximately 225,000 flies, using a model developed for genetic analysis of age-dependent traits (the character process model). Both within- and among-generation analyses suggest that the input of genetic variance is greater for early life mortality rates than for mortality at older ages. In females, age-specific mutational variances ranged over an order of magnitude from 5.96 x 10(-3) at 2 wk posteclosion to 0.02 x 10(-3) at 7 wk. The male data show a similar pattern. Age-specific genetic variances were substantially less at generation 47 than at generation 19-an unexplained observation that is likely due to block effects. Mutational correlations among mortality rates at different ages tend to increase with the accumulation of new mutations. Comparison of the mutation-accumulation lines at generations 19 and 47 with their respective control lines suggests little age-specific mutational bias. 相似文献
18.
Brian Charlesworth 《Evolution; international journal of organic evolution》1990,44(3):520-538
The process of selection on a multivariate set of characters subject to functional constraints is considered from the points of view of both evolutionary optimization theory and quantitative genetics. Special attention is given to life-history characteristics. It is shown that, under suitable conditions (including weak selection), useful approximate formulas for the relations between the functional constraints and the additive genetic variance-covariance matrix can be derived. These can be used to show that the conditions for equilibrium under selection according to the two different approaches are approximately equivalent. Although large negative genetic correlations are to be expected between some pairs of life-history traits in populations at equilibrium under selection, in general some small negative genetic correlations and some positive genetic correlations will also be present. Thus, the observation of a positive genetic correlation between a pair of life-history traits does not necessarily refute the possibility of trade-offs among a multivariate set of traits that contains the pair in question. The relation between the pattern of functional constraints and the genetic correlations is often complex, and little insight into the former can be derived from the latter. The effects of mutations that lower the overall efficiency of resource utilization, thereby creating a positive component to the genetic covariances among life-history traits, are also considered for a specific model. Although such mutations can have a substantial effect on the form of the life history, extreme conditions seem to be needed for them to produce a large effect on the pattern of genetic correlations in a random-mating population. They can, however, cause the appearance of positive correlations following inbreeding, due to the exposure of deleterious recessive or partially recessive mutations. The analysis also suggests that the population means of individual components of a constrained multivariate system may often equilibrate at values that are far from the optima that would be attained if they were selected in isolation from the other members of the system. 相似文献
19.
The rare alleles model of mutation-selection balance (MSB) hypothesis for the maintenance of genetic variation was evaluated for two quantitative traits, ovariole number and body size. Mutational variances (VM) for these traits, estimated from mutation accumulation lines, were 4.75 and 1.97 x 10(-4) times the environmental variance (VE), respectively. The mutation accumulation lines were studied in three environments to test for genotype x environment interaction (GEI) of new mutations; significant mutational GEI was found for both traits. Mutations for ovariole number have a quadratic relationship with competitive fitness, suggesting stabilizing selection for the trait; there is no significant correlation between mutations for body size and competitive fitness. Under MSB, the ratio of segregating genetic variance, VG, to mutational variance, VM, estimates the inverse of the selection coefficient against a heterozygote for a new mutation. Estimates of VG/VM for ovariole number and body size were both approximately 1.1 x 10(4). Thus, MSB can explain the level of variation, if mutations affecting these traits are under very weak selection, which is inconsistent with the empirical observation of stabilizing selection, or if the estimate of VM is biased downward by two orders of magnitude. GEI is a possible alternative explanation. 相似文献
20.
Adult reproductive success can account for a large fraction of male fitness, however, we know relatively little about the susceptibility of reproductive traits to mutation-accumulation (MA). Estimates of the mutational rate of decline for adult fitness and its components are controversial in Drosophila melanogaster, and post-copulatory performance has not been examined. We therefore separately measured the consequences of MA for total male reproductive success and its major pre-copulatory and post-copulatory components: mating success and sperm competitive success. We also measured juvenile viability, an important fitness component that has been well studied in MA experiments. MA had strongly deleterious effects on both male viability and adult fitness, but the latter declined at a much greater rate. Mutational pressure on total fitness is thus much greater than would be predicted by viability alone. We also noted a significant and positive correlation between all adult traits and viability in the MA lines, suggesting pleiotropy of mutational effect as required by 'good genes' models of sexual selection. 相似文献