Propuesta de desarrollo de una unidad de oncogeriatría. Tiempos de cambio: nuestra realidad

Age is one of the main risk factors for the development of cancer. It is expected that the progressive aging of the population will have an unprecedented impact on the incidence of various tumours. In fact, the management of elderly cancer patients is already a major public health problem in developed countries. However, elderly patients have systematically been excluded from cancer drug studies or protocol development. This has left health professionals in uncharted territory, without proper tools to address the multiple difficulties that arise in the treatment of these patients. A comprehensive geriatric assessment may serve as an ideal tool for the correct detection of hidden problems, facilitating treatment decisions in these complex patients, and integrating the care of patients with comorbidities.     

Étude des parois de levures du genre Rhodotorula. X. Isolement et purification de glycoprotéines de la paroi de Rhodotorula rubra

Following ethylene diamine treatment of the cell wall of Rhodotorula rubra, a water soluble fraction has been isolated. This fraction can be resolved into three glycoproteins and one protein. The major part is a glycoprotein, purified to homogeneity which has a molecular weight of 64 000. The glyco-part of this protein contains mannose, glucose and one residue of glucosamine. After pronase treatment, the presence of an “Asparaginyl-N-acetylglucosamine” linkage is established by the existence of one aspartic acid residue and one glucosamine residue. After permethylation, the initial data give some evidence that the branching points in the molecule were the carbon atoms 3 and (or) 6 of the mannose moiety and that some glucose moieties are bound to the non-reducing terminal end.     

La fracture de verge à Dakar. à propos de 25 cas

Objectives

To describe the epidemiological, clinical and therapeutic characteristics of penile fracture in the department of Urology-Andrology of h?pital général de Grand Yoff, Dakar, Sénégal.

Materials and methods

We reviewed the medical records of cases of penile fracture managed at the h?pital général de Grand Yoff from January 2001 to December 2011. The data of interest were: age at diagnosis, geographic origin, clinical presentation, surgical findings, treatment and outcomes.

Results

In ten years, 25 cases of penile fracture were found with an average of 2,5 cases per year and patients mean age of 36 years with 22 and 60 years as extremes. The circumstances of occurrence were mainly forced manipulation (52%) and coitus (32%). Pain associated with penile curvature, swelling localized to the penis or extending to the pubis or the perineum were the major clinical findings. A prompt emergency (mean time for providing care was 2 hours ranging from 45 minuts to 2 days) surgical explorationwith suture of the albuginea of the corpus cavernosum was the treatment in all cases.

Conclusion

Penile fracture is a relatively uncommon urological emergency in our setting. The diagnosis is easy, mostly based on clinical examination. A prompt and appropriate surgical management is the key to cosmetic and functional outcomes.     

Vitamines et facteurs de croissance chez les plantes. Recherches sur la solubilité des facteurs de croissance. Le facteur de l'urine

Sans résumé     

Influence de l’action combinee du P.A.S. et de l’hydrazide isonicotinique (INH) sur l’augmentation de la resistance de bacilles tuberculeux in vitro

Résumé Un examen comparatif in vitro fait ressortir que l’augmentation de la résistance des bacilles tuberculeux vis-à-vis d’un mélange d’INH et de P.A.S. ne se présente pas ou seulement lentement après des ensemencements successifs sur des milieux qui contiennent ce mélange. Ceci à l’opposé de bacilles exposés a l’influence de ces deux éléments isolés. Les bacilles qui subissent l’influence du mélange font voir également une légère augmentation de la résistance à l’égard des composants isolés. Les travaux de recherches furent supportés en partie par Riker Laboratories Inc., Los Angeles, California.