A historical perspective on the collaboration between psychoanalysis and neuroscience

The aim of this article is to present and discuss the connections between psychoanalysis and neuroscience from a historical viewpoint. We start by examining how Sigmund Freud can be viewed as a pioneer in the interaction between these two fields. Freud was himself a neurologist and had maintained an interest in biology as he developed the key concepts of psychoanalysis. His ideas regarding psychosomatics are described. We will also explore how the concept of drive is essential to the connection between psychoanalysis and neuroscience. Then, we describe several key actors and historical events and characters at the interface of these two fields, namely Sándor Radó Lawrence S. Kubie and Mc Culloch, the debates that took place during the Macy conferences, as well as the positions of Jacques Lacan, George L. Engel, and Eric Kandel. Finally, we present a synthesis of the main fields in which the connections between psychoanalysis and neuroscience are already fruitful, and those where they should be developed: the classification of mental diseases, the link between the scientific and psychic dimensions, therapeutics, the organization of the body, intersubjectivity, the subjective division and ambivalence, as well as transferential effects like such as the placebo and nocebo effects. In the conclusion, we advocate several strategic alliances and underscore the complementarity between rigorous scientific experimentation and the individualized psychoanalytic approach.     

The law and neuroscience

Some of the implications for law of recent discoveries in neuroscience are considered in a new program established by the MacArthur Foundation. A group of neuroscientists, lawyers, philosophers, and jurists are examining issues in criminal law and, in particular, problems in responsibility and prediction and problems in legal decision making.     

The relationships between dream content and physical health, mood, and self-construal.

Research is presented that examines the relationship among dream content, physical health, mood, and self-construal. Participants were 27 undergraduate students who completed the Medical Outcomes SF-36 Health Survey (SF-36), the Profile of Mood States Scale (POMS-SF), and the Self-Construal Scale (SCS). Each participant handed in four dream reports, which were analyzed according to the Hall and Van de Castle (1966) system of content analysis. Multiple significant correlations were observed between dream content and the SF-36, the POMS-SF, and the SCS. Most notable were the findings between physical health and dream content. Participants displaying poor physical health reported more bodily misfortunes, injuries and illnesses, medical themes, and body parts in their dreams. Findings support continuity between dreams and waking life physical and mental functioning. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The neuroscience of grasping

People have always been fascinated by the exquisite precision and flexibility of the human hand. When hand meets object, we confront the overlapping worlds of sensorimotor and cognitive functions. We reach for objects, grasp and lift them, manipulate them and use them to act on other objects. This review examines one of these actions--grasping. Recent research in behavioural neuroscience, neuroimaging and electrophysiology has the potential to reveal where in the brain the process of grasping is organized, but has yet to address several questions about the sensorimotor transformations that relate to the control of the hands.     

Comparison of dream anxiety and subjective sleep quality between chronotypes

Morning and evening-type individuals differ on a number of psychological and biological variables. In this study, we aimed to investigate the relationship between sleep quality, dream anxiety, and chronotypes. A sample of 264 university students, aged between 17 and 26 years, completed the Morningness-Eveningness Questionnaire, the Pittsburgh Sleep Quality Index, and the Van Dream Anxiety Scale for assessing nightmare frequency and the dream anxiety caused by frightening dreams. Main findings indicated that evening-type individuals were significantly more likely to suffer from poor sleep quality, daytime dysfunction, nightmares, and nightmare-related disturbances as compared to either intermediate- or morning-type individuals. Previous studies have pointed out the possible connections of irregular sleep-wake habits and circadian dysregulation with a tendency to reveal eveningness chronotypical characteristics. Current findings suggest that evening-type individuals are more prone to experience psychologically deteriorating nightmares and sleep-related anxiety. Poor sleep quality is also a significant antecedent of dream anxiety after controlling for age and gender.

     

The neuroscience of remote memory

Recently, there has been renewed interest in the organization and neurobiology of remote memory, and the pace of work in this area has accelerated. Yet the recent literature does not suggest that a consensus is developing, and there is disagreement about both facts and their interpretation. This article undertakes a comprehensive review of the three kinds of evidence that have been most prominent in recent discussion: studies of retrograde amnesia in memory-impaired patients who have well-characterized lesions, neuroimaging of healthy volunteers, and work with experimental animals including lesion studies, imaging and mouse genetics. The available evidence tells a coherent story and leads to some straightforward conclusions about the neuroscience of remote memory.     

The structure of dream sequences

The present study examines the relationships between dreams reported by a subject in the course of two nights in a sleep laboratory. The method used is derived from Lévi-Strauss's structural analysis of myth. The dreams are shown to constitute a set of systematic transformations of a single structure. The structure itself is formed by a set of oppositions, which in part represent a dilemma or conflict facing the dreamer. In the course of the night's dreams a series of transformations of the problem are generated and scanned. These transformations are governed by regular quasi-logical procedures.     

The dream world in Dominica.

To the natives of the Caribbean island of Dominica, the dream is proclaimed la konpanyi la nuit (the companion of the night). Belief in dreams is grounded in diverse cultural influences, including those of the French, West African, British, and the doctrines of the Roman Catholic Church. In this richly imaginative dream world, myths and truths are finely interwoven to create an unwritten glossary of dream symbol interpretation. Although these interpretations have not enjoyed scientific validation, practical, historical, and psychological data are found to resonate with these traditional Dominican interpretations. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The neuroscience of affiliation: forging links between basic and clinical research on neuropeptides and social behavior

Animal studies point to the role of two neuropeptides-oxytocin and vasopressin-in the regulation of affiliative behaviors including mating, pair-bond formation, maternal/parenting behavior, and attachment. These findings may have important implications for understanding and treating clinical disorders marked by social deficits and/or disrupted attachment. This review focuses on advances made to date in the effort to forge links between basic and clinical research in the area of neuropeptides and social behavior. The literature on oxytocin and its involvement in stress response, affiliation, and prosocial behavior is reviewed, and the implications of these findings for such disorders as autism as well as other social and stress-related disorders including social phobia, post-traumatic stress disorder, and some personality disorders are considered. Finally, unresolved issues and directions for future research are discussed.     

The status of cognitive neuroscience.

Cognitive neuroscience rests on findings, methods, and theory from three fields: experimental psychology, systems-level neuroscience, and computer science. The strong trend over the past few years has been for a greater integration across these fields. The influence of this interdisciplinary approach on current research on memory, perception, and language will be illustrated.     

The cognitive neuroscience of memory distortion

Memory distortion occurs in the laboratory and in everyday life. This article focuses on false recognition, a common type of memory distortion in which individuals incorrectly claim to have encountered a novel object or event. By considering evidence from neuropsychology, neuroimaging, and electrophysiology, we address three questions. (1) Are there patterns of neural activity that can distinguish between true and false recognition? (2) Which brain regions contribute to false recognition? (3) Which brain regions play a role in monitoring or reducing false recognition? Neuroimaging and electrophysiological studies suggest that sensory activity is greater for true recognition compared to false recognition. Neuropsychological and neuroimaging results indicate that the hippocampus and several cortical regions contribute to false recognition. Evidence from neuropsychology, neuroimaging, and electrophysiology implicates the prefrontal cortex in retrieval monitoring that can limit the rate of false recognition.