Effectiveness of hypoglycemic agents in guinea pigs exposed to mixed gamma-neutron radiations

The effect of 200, 1000, and 5000 rads of mixed gamma-neutron radiations on total blood reducing sugar and blood glucose levels in guinea pigs was investigated 2 and 24 hours, and 9, 22, and 60 days postirradiation. In addition, the effectiveness of insulin and tolbutamide in these animals was evaluated before and after irradiation. Glucose increased to a lesser degree and later than did the nonglucose fraction of the blood sugar. Insulin and tolbutamide were at least as effective in irradiated animals as in unirradiated ones except after 5000 rads, when tolbutamide was significantly less effective. These results suggest that: (1) insufficient insulin is released by the pancreas in response to elevated blood sugar levels following irradiation; (2) the pancreas does produce insulin at these times and is able to release it in response to tolbutamide; and (3) a decrease in insulin production occurs following supralethal doses of radiation.     

Action of mixed gamma-neutron radiation with various dose rates on the number of cells in thymus and chromosomes of mice bone marrow and human lymphocytes

The irradiation with mixed gamma-neutron radiation was carried out at the pulse nuclear reactor on fast neutrons BARS-6 in a regimen of one pulse (100 micros) and in a regimen of continuous irradiation during 60 minutes. Was shown, that the irradiation of mice with pulse radiation was 1.3-1.8 times more effective in the induction of the chromosome aberrations in bone marrow cells in comparison with the continuous regimen of irradiation. At the same time, other biological tests (yield of chromosome aberrations in human lymphocytes, decreasing the number of cells in thymus) demonstrated that pulsed and continuous regimens have almost equal biological effectiveness.     

双歧杆菌发酵果蔬汁对小鼠免疫功能的影响

目的研究双歧杆菌发酵果蔬汁对小鼠免疫功能的影响。方法将小鼠随机分成纯净水对照组与发酵果蔬汁低、中和高3个剂量组,饮水法喂饲小鼠,测定小鼠胸腺和脾脏指数、腹腔巨噬细胞吞噬功能、血清溶血素测定、皮肤迟发型超敏反应(DTH)程度。结果与对照组比较,3种果蔬汁能显著增强巨噬细胞吞噬功能,增加血清溶血素抗体水平和DTH程度。结论双歧杆菌发酵果蔬汁能提高机体的免疫功能。     

Radiolysis of liposomes, of solutions of ferrous sulphate and of albumin mixed by gamma-neutron radiation at different dose rates

Solutions of the ferrous sulfate, of the albumin and of the suspension of liposomes were irradiated by mixed gamma-neutron radiation (fission spectrum neutrons, contribution of gamma-component to the absorbed dose up to 20%) at the pulse reactor BARS-6 with single-pulse (duration 100 micros) or continuous radiation (duration 60 min). It was shown, that after the pulse irradiation the concentration of the malonic dialdehyde in liposomes was in 3-4 times higher than after the continuous radiation at equal absorbed doses (p < 0.05). On the contrary, the irradiation of the liposomes suspension as well as of the solutions of the ferrous sulfate and of the albumin in a mode of single-pulse or of continuous mode did not reveal the statistically significant differences in the production of Fe3+ ions and of peroxides of the albumin for two mode of the radiation action.     

Effect of red, far-red radiations on germination of cotton seed

Seeds of two cultivars, H-14 and J-34 of Gossypium hirsutumL. soaked in the dark for durations of 8, 12 and 16 hr wereexposed to red and far-red radiations alone and in differentsuccessions. While cv. J-34 was unresponsive to all light treatments,seed germinaiton in cv.H-14 was promoted by darkness and byexposure to far-red radiation and was inhibited by red andwhitelight.Seed germination depended upon what treatment was given at theend. The effect ofred light was reversed by far-red and viceversa. Although instances of light inhibition of seed germinationare known, the authors are not aware of any clear cut instancein the literature on far-red promotion of seed germination (Received November 4, 1970; )