A diterpene from Euphorbia maddeni

From the anticancer-active CHCl₃, extract of the plant Euphorbia maddeni, a polyacylated diterpene of jatrophone type, euphornin, has been isolated and its structure elucidated by physico-chemical methods.     

Isocrotocaudin,A new norclerodane-type diterpene from Croton caudatus

Isocrotocaudin, a new furanoid norditerpene (norclerodane type), has been isolated from the petrol extract of the stem-bark of Croton caudatus (Eup     

Two diterpene alcohols from Croton sublyratus

The isolation and structural elucidation of two diterpene alcohols from Croton sublyratus are described. These compounds are ent-3α-hydroxy-13-epimanool and ent-16β,17-dihydroxykaurane.     

Two cleistanthane type diterpenes from Croton sonderianus

Sonderianol (12-hydroxy-3-oxo-cleistanth-8, 11, 13, 15-tetraene) and 3, 4-seco-sonderianol (methyl 12-hydroxy-3, 4-seco-cleistanth-8, 11, 13, 15, 18(4)-penten-3-oate), two new diterpenes with cleistanthane skeletons, were isolated from heartwood of Croton sonderianus.     

Sonderianin,a furanoid diterpene from Croton sonderianus

From the heartwood of Croton sonderianus was isolated a new furanoid diterpene, sonderianin. The structure was elucidated by spectral analysis, X-ray studies and chemical evidence.     

Lathyrane type diterpene esters from Euphorbia lathyris

By reversed phase HPLC ‘ester L₇’, previously isolated among several macrocyclic lathyrol derivatives from seeds of Euphorbia lathyris, was     

A diterpene acid from baccharis tucumanensis

The new clerodane diterpene 1 was isolated from the aerial parts of Baccharis tucumanensis (Compositae). Its structure has been determined from spectral data combined with chemical transformations.     

Roseadione,a diterpene ketone from Hypoestes rosea

A tricyclic diterpene ketone, roseadione, has been isolated from Hypoestes rosea and its structure established as a dicyclopenta[a, d]cyclo     

Diasin,A diterpene from Croton diasii

The trunkwood of Croton diasii Pires (Euphorbiaceae) contains diasin, a novel rearranged labdanic diterpene which includes furan, carbomethoxy, γ     

Sempervirenic acid,a diterpene acid from Solidago sempervirens

Sempervirenic acid, a new diterpene has been isolated from Solidago sempervirens and its structure determined by spectroscopic methods and chemical conversions to be 3β-acetoxy-labda-7,13-diene-15-oic acid.     

The structure and stereochemistry of phlogantholide-A,a diterpene from Phlogacanthus thyrsiflorus

The structure and stereochemistry of phlogantholide-A, a new diterpene lactone isolated from the leaves of Phlogacanthus thyrsiflorus has been determined as 2β,15,18-trihydroxy-ent-labd-8(17),13-dien-16-oic lactone by chemical and spectroscopic means.     

Alkaloid biosynthesis in Croton flavens

The biosynthesis of the morphinandienone alkaloids norsinoacutine, sinoacutine and flavinantine has been studied using 1-³ H-sinoacutine, 1-³H-norsinoacutine, 1-³H-norsinoacutinols, l-[S-methyl-¹⁴C]-methionine, glycine-2-¹⁴C, 1-³H-8,14-dihydronorsalutaridine, 1-³ H-8,14-dihydrosalutaridine, 1-³H-sinomenine, 1-³H-isosinomenine, (±)-[2-¹⁴C]phenylalanine, (±)-[N-methyl-¹⁴C]orientaline and (±)-[N-methyl-¹⁴C]reticuline.     

Grayanoside C,a new diterpene glucoside from Leucothoe grayana

A new diterpene glucoside has been isolated from Leucothoe grayana. Its structure was elucidated by X-ray diffraction analysis of a dehydrated product of the aglycone and conversion of the same to leucothol A.     

Genkwadaphnin,a potent antileukemic diterpene from Daphne genkwa

In vivo P-388 assay-directed fractionation of an active extract of Daphne genkwa (Yuán Huā) has led to the isolation and characterization of a new antileukemic principle. genkwadaphnin.     

An abietane diterpene from the labiate Coleus barbatus

20-Deoxocarnosol, isolated from the stems of Coleus barbatus, was shown by chemical and spectral methods to be a new phenolic diterpene with an abietane skeleton.     

Two oxepane-type diterpene lactones from melampodium diffusum

The isolation and structure elucidation of two new oxepane diterpene lactones, 1,10,17-trihydroxymelfusanolide and 1,10-dihydroxy-17-acetoxymelfusanolide, from Melampodium diffusum are reported. The structure determination involved chemical and spectral methods.     

3α-Angeloyloxy-2α-hydroxycativic acid,a new diterpene from Brickellia paniculata

The investigation of Brickellia paniculata resulted in the isolation of a new diterpene of the labdane type. It was identified as 3α-angeloyloxy-