Isolation,characterisation and antifungal activity of marine actinobacteria from Goa and Kerala,the west coast of India

In total, 53 marine actinobacteria were isolated from the soils of six different locations in Goa and Kerala, on the west coast of India. All the isolates were screened for their antifungal properties against some phytopathogenic fungi by dual culture experiments. Among the 53 actinobacterial isolates, five isolates inhibited the growth of phytopathogens, namely Colletotrichum falcatum, Thielaviopsis paradoxa and Fusarium semitectum. But none of them were effective against Aspergillus niger, Aspergillus candidus and Aspergillus flavus. The antifungal activity of the actinobacteria was tested by food poisoning techniques, using four different concentrations (0.5%, 1.0%, 1.5% and 2.0%) of cell-free culture filtrates, which showed promising activity (almost 100% inhibition) against three pathogenic and one non-pathogenic fungi at 2% extract concentration. A comparison of the antifungal activity of the actinobacteria was also made with three commercial fungicides, namely hexaconazole, thiophanate methyl and propiconazole. The identity of the antagonistic actinobacteria was confirmed based on the morphological, cultural, biochemical, chemo-taxonomical and physiological characteristics. Among 5 antagonistic isolates, three antagonistic isolates were assigned to the genus Streptomyces, Nocardiopsis (1) and Saccharopolyspora (1).     

Household and community socioeconomic influences on early childhood malnutrition in Africa

This paper uses multilevel modelling and Demographic and Health Survey data from five African countries to investigate the relative contributions of compositional and contextual effects of socioeconomic status and place of residence in perpetuating differences in the prevalence of malnutrition among children in Africa. It finds that community clustering of childhood malnutrition is accounted for by contextual effects over and above likely compositional effects, that urban-rural differentials are mainly explained by the socioeconomic status of communities and households, that childhood malnutrition occurs more frequently among children from poorer households and/or poorer communities and that living in deprived communities has an independent effect in some instances. This study also reveals that socioeconomic inequalities in childhood malnutrition are more pronounced in urban centres than in rural areas.     

Child mortality in Goa: A cross‐sectional analysis

Abstract

This paper is a study of the determinants of child mortality in the relatively developed Indian state of Goa. Data from the National Family Health Survey (NFHS, 1992–93) conducted in the state of Goa have been used to examine the child mortality experiences of 1,331 women who were within a marriage lasting 15 years. An aggregated index of child mortality, which summarizes the mortality experiences of a woman with exposure adjustment, is the study variable. Maternal education and longer birth spacing were found to lower child mortality risks significantly.     

The impact of childhood malnutrition on schooling: evidence from Bangladesh

This paper examines the impact of childhood malnutrition on schooling performance in rural Bangladesh. The results reveal that malnourished children are less likely to enrol in school on time and achieve an age-appropriate grade by 26 percentage points and 31 percentage points, respectively. Other important determinants of schooling outcomes include infrastructure and education level of parents. One major contribution of this paper is the control for the endogeneity of malnutrition status, which otherwise might lead to bias estimates.     

Haplotype analysis of the polymorphic 17 YSTR markers in Kerala nontribal populations

The origin of the Kerala non tribal population has been a matter of contention for centuries. While some claim that Negritos were the first inhabitants, some historians suggest a Dravidian origin for all Keralites. The aim of our study has been to provide sufficient scientific evidence based on Y chromosome short tandem repeat (Y STR) analysis for tracing the paternal lineage and also to create a database of the Y STR haplotype of the male population for future forensic analysis. Whole blood samples (n = 168) were collected from unrelated healthy men of the Kerala non-tribal population over a period of 2 years from October 2009. Genomic DNA was extracted by salting out method. All samples were genotyped for the 17 Y STR loci by the AmpFLSTR Y-filer PCR Amplification Kit. The haplotype and allele frequencies were determined by direct counting and analyzed using Arlequin 3.1 software, and molecular variance was calculated with the Y chromosome haplotype reference database online analysis tool, . Haplotype diversity was calculated using HaPYDive (). The majority of haplotypes were unique (149/168). The variant allele 17.1 was observed in DYS 385 loci in three samples. Fifteen samples (8.93%) showed the presence of alleles that are not within the established marker range denoted as outside marker range (OMR). The allele frequency of Kerala non tribal population ranged from 0.00003 to 0.5809. The most polymorphic single locus marker was DYS 458. The haplotype diversity value for Kerala non tribal population was 0.9978. The pairwise difference value ranged from 0.0531 to 0.0854 on comparison of the haplotypes of the Kerala non tribals with other Indian populations. The multi dimensional scaling plot depicted the proximity of Kerala non tribal population with Vasterbotten population (Swedish) and Paiwan, Patyal population of Taiwan, Thailand, and Zhuang population of China. The results of the study indicate towards a European paternal lineage in the non tribal Kerala population.     

Hairy pinnae in Kerala

The study of hairs on the different parts of the pinna of adult males among the endogamous groups of Kerala province, India, revealed age trends, differences among the groups, and high correlations between the frequency of hairs in certain regions of the ear. The greatest incidence of hypertrichosis was found in the lower helix, followed by the tragus, middle helix, lobe, and top of helix. A gradual increase in the frequency of the trait with age occurred in the antitragus and tragus, and a decrease with age in the lower and middle helix. As hair at the top of the helix remains constant in frequency with age and is present in all populations studied, it is a useful anthropological marker.     

Screening for acute childhood malnutrition during the National Nutrition Week in mali increases treatment referrals

Objective

To evaluate a pilot intervention designed to integrate mid-upper arm circumference (MUAC) screening for acute malnutrition into the semi-annual Child Nutrition Week (Semaine d''Intensification des Activités de Nutrition, or “SIAN”) activities carried out in June 2008.

Design

A cross-sectional survey was conducted in Kolokani and Nara, two health districts in the Koulikoro region of Mali, 4–5 months after the SIAN, using a population-proportionate, multi-stage random sample of: 1) health centers, and 2) households in communities linked to each of the selected health centers. Caregivers of 1543 children who were 6–59 months of age at the time of the SIAN, 17 community-based volunteers and 45 health center staff members were interviewed.

Results

A total of 1278 children 6–59 months (83% of those studied) reportedly participated in SIAN. Of the participating children, 1258 received vitamin A (98% of SIAN participants; 82% of all eligible children), 945 received anti-helminth tablets (84% of participants; 71% of eligibles), and 669 were screened for acute malnutrition (52% of participants; 43% of eligibles). 186 of the children screened (27%) were reportedly identified as acutely malnourished. SIAN screening covered a significantly greater proportion of children than were examined in both community-based (22% of children) and health center-based screening activities (5% of children) combined during the 4-5 months after the SIAN (P<0.0001). In general, community volunteers and health personnel positively evaluated their experience adding MUAC screening to SIAN.

Conclusion

Integrating MUAC screening for acute malnutrition in SIAN permits the assessment of a large number of children for acute malnutrition, and should be continued.     

Migration, Money and Masculinity in Kerala

This article examines migration, styles of masculinity and male trajectories through the life-cycle in Kerala, South India, in a region with a long history of high migration, most lately to the Persian Gulf states. Ethnography suggests that migration may be integrated into wider identity projects and form part of local subjectivities. The article considers four important local categories: the gulfan migrant, typically an immature unmarried male; the kallan , a self-interested maximizer or individualistic anti-social man; the pavam , an innocent good-guy, generous to the point of self-destruction; mature householder status, a successful, social, mature man holding substantial personal wealth, supporting many dependents and clients. Another theme to emerge is the relationship between masculinity and cash: migration appears as particularly relevant to masculinity in its enhanced relationship with money, an externalizable (detachable) form of masculine potency: maturity means being able to use such resources wisely.     

A Clinico-Mycological Study of Dermatophytoses in Goa,India

The study was a clinico-mycological approach to find out the various clinical types of dermatophytoses and as well as the species of dermatophytes in Goa. Various socio-demographic and host factors were assessed to determine the predisposing factors for dermatophytoses. A detailed clinical history of the patients was recorded. Samples were collected aseptically in sterile black paper envelopes. The material was subjected to microscopy using potassium hydroxide mount. Culture was done by inoculating the material in Sabouraud’s peptone glucose agar slants. Tinea corporis was found to be the most common clinical presentation (44.2 %). Among the dermatophytes, Trichophyton rubrum predominated (38.2 %), followed by Trichophyton mentagrophytes (27.2 %). Dermatophytoses was more common among the lower and upper lower strata of society. Majority of the patients were in the 21–40 years age group (62 %) with males predominating women in ratio 2.4:1.     

Education, fertility and contraception among Hindus and Roman Catholics in Goa

Differences in age at marriage, fertility and contraceptive use are related to religious background, individual educational level and community level education. In general, the effects of community education are weak compared to individual level of education, but differences exist between Hindus and Roman Catholics.     

Stimulation and conformational change of Goa induced by GAP-43

GAP-43, a major component of the neuronal growth cone is closely correlated with neural development and regeneration[1—5]. Go is the predominant noncytoskeletal protein in the growth cone membrane[6]. It is a kind of heterotrimeric GTP-binding proteins, which transduce signals across the plasma membrane by coupling between receptors and effectors[7]. Stimulation or inhibi-tion of G proteins altered neurite outgrowth[3]. Mastoparan, which activates heterotrimeric G pro-teins of the Go and …     

Growth and malnutrition in Ethiopia

This article focuses on anthropometric parameters as height for age, weight for age and weight for height, which are among the most used tools for assessing well-being of infants and children. Such data have been collected between 1992--1993 from samples of infants and children aged between 2 and 10 years from urban and rural areas of Ethiopia. Similar to many other reports from developing countries the great amount of malnourished children is preoccupying as reflected by about 15% of children below the 5th centile of weight for height and about 53% of children below the 5th centile of height for age and about 45% below the 5th centile of weight for age.     

Metagenomic analysis exploring taxonomic diversity of rumen microbial communities in Vechur and crossbred cattle of Kerala state,India

Rumen, one of the most productive diverse microbial habitats plays a vital role in the breakdown of feed to produce energy for maintenance and milk production in cattle. Culture-based procedures...     

Production of dimethylsulphide during the seasonal anoxia off Goa

Subsurface waters over the western Indian continental shelf experience seasonal anoxia towards the end of the southwest monsoon season. During a 3-day study carried out at the Candolim time series site (off the coast of Goa), dimethylsulphide (DMS) concentrations showed a 40-fold increase to a maximum of 442?nM at 25?m depth compared to the oxygenated surface waters. This extremely high DMS was found to be associated with relatively low chlorophyll a, low phytoplankton cell counts and a high concentration of hydrogen sulphide. However, total dimethylsulphoniopropionate, total dimethylsulphoxide and methanethiol concentrations were quite low and unlikely to account for the DMS build-up through presently known pathways of DMS production. While there are several possible mechanisms for the observed accumulation of DMS, we were unable to pinpoint the exact pathway of DMS production. Future work will involve investigation of the source of DMS through sediment slurry experiments, to explore this interesting link between the carbon and sulphur cycles under anoxic conditions.     

Distribution of sub-littoral meiobenthos off Goa coast,India

Vertical and horizontal distribution of meiofauna was studied off Goa coast. Bottom deposit included mainly fine sand and silt. Total number of animals ranged from 250 to 2925/10 cm². Highest faunal density was in the top 6 cm layer. The fauna consisted of two main groups, nematodes and foraminiferans which together formed 60 to 80% of the total meiofauna. Fine sand supported a rich fauna. Interstitial water and organic content of the sediment was found to be the limiting factor in the distribution of meiobenthos.     

An SEIQR model for childhood diseases

It has been shown that the inclusion of an isolated class in the classical SIR model for childhood diseases can be responsible for self-sustained oscillations. Hence, the recurrent outbreaks of such diseases can be caused by autonomous, deterministic factors. We extend the model to include a latent class (i.e. individuals who are infected with the disease, but are not yet able to pass the disease to others) and study the resulting dynamics. The existence of Hopf bifurcations is shown for the model, as well as a homoclinic bifurcation for a perturbation to the model. For historical data on scarlet fever in England, our model agrees with the epidemiological data much more closely than the model without the latent class. For other childhood diseases, our model suggests that isolation is unlikely to be a major factor in sustained oscillations.