Ion mobility-mass spectrometry strategies for untargeted systems,synthetic, and chemical biology

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Change,exchange, and rearrange: protein engineering for the biotechnological production of fuels,pharmaceuticals, and other chemicals

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A DNA-Damage Selective Role for BRCA1 E3 Ligase in Claspin Ubiquitylation,CHK1 Activation,and DNA Repair

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Highlights? BRCA1 E3 ligase activity is essential for a subset of DNA damage responses ? BRCA1 V26A mutant cells are sensitive to topoisomerase inhibitors but not mitomycin C ? BRCA1 selectively ubiquitylates claspin after topoisomerase inhibition ? BRCA1 E3 ligase inactivation selectively impairs CHK1 activation     

Bacterial chemotaxis: information processing,thermodynamics, and behavior

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Agricultural soils,pesticides and microbial diversity

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Tau imaging in the study of ageing,Alzheimer's disease,and other neurodegenerative conditions

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Information theory of adaptation in neurons,behavior, and mood

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Catalytic control in terpenoid cyclases: multiscale modeling of thermodynamic,kinetic, and dynamic effects

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Protein folding,binding, and droplet formation in cell-like conditions

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Female Penis,Male Vagina,and Their Correlated Evolution in a Cave Insect

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Environmental sensing,information transfer,and cellular decision-making

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L-Arabinose Binding,Isomerization, and Epimerization by D-Xylose Isomerase: X-Ray/Neutron Crystallographic and Molecular Simulation Study

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The Earliest Transcribed Zygotic Genes Are Short,Newly Evolved,and Different across Species

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The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type

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Highlights? MYC and MET affect glucose and glutamine metabolism differently in the liver ? Tissue context affects the outcome of metabolic reprogramming by MYC ? MYC overexpression sensitizes cells to inhibition of Gls1 glutaminase     

Phylogenomics Resolves Evolutionary Relationships among Ants,Bees, and Wasps

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The Ratio of Macronutrients,Not Caloric Intake,Dictates Cardiometabolic Health,Aging, and Longevity in Ad Libitum-Fed Mice

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Optimization of a single HPLC-PDA method for quantifying Metformin,Gliclazide, Pioglitazone,Dapagliflozin, Empagliflozin,Saxagliptin, Linagliptin and Teneligliptin using central composite design

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The small intestine microbiota,nutritional modulation and relevance for health

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Extracellular vesicles: exosomes,microparticles, their parts,and their targets to enable their biomanufacturing and clinical applications

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Towards a predictive systems-level model of the human microbiome: progress,challenges, and opportunities

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