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1.
E V Rusinova V I Davydov V N Mats 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1989,39(3):520-526
By the method of spectral-coherent analysis the dynamics was studied of successive changes in the structure the rabbit brain electrical activity coherent relations in the process of formation of motor polarization dominant created by DC anode action on the sensorimotor cortical region. It has been shown that at earlier stages, when the motor "dominant" reaction is absent, there appears an interhemispheric asymmetry in Coh spectra of electrical activity of the sensorimotor cortex and of the thalamus VPL. On the contrary, interhemispheric asymmetry in Coh spectra of electrical activity of the sensorimotor cortex and dorsal hippocampus CA3 field appears only at the stage when the motor "dominant" reaction is recorded. Asymmetry in alpha- and beta-frequencies ranges in biopotentials Coh spectra of the studied regions coinciding with the motor "dominant" reaction realization is connected with processes of movement organization. 相似文献
2.
E V Rusinova 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1987,37(2):305-312
By the method of spectral-correlation analysis, the dynamics was studied of changes in intercentral relations of electrical activity in the sensorimotor and premotor cortices of both cerebral hemispheres during formation, course, recovery and extinction of motor dominant created by a single action of DC anode in rabbits sensorimotor cortex. The motor dominant is capable to be preserved during the test for a long time after DC switching off and to recover in subsequent days under the action of testing stimuli. It should be noted that the recovery of the structure of intercentral relations of electrical brain activity, characteristic of dominant state, takes place much earlier than the motor "dominant" reaction. 相似文献
3.
E V Rusinova 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1988,38(3):497-505
By the method of spectral-coherent analysis, the intercentral relations were studied of the electrical activity of the sensorimotor and premotor cortices and of CAs field of the dorsal hippocampus of both hemispheres during the motor polarization dominant, created by the action of the direct current on the rabbits sensorimotor cortical area. The formation was shown of a new structure of the intercentral relations of electrical activity of the sensorimotor cortex and CA3 of the dorsal hippocampus. It should be noted that the dominant optimum and its inhibition are characterized by different interhippocampal relations: at the optimum a low range of the theta-rhythm is highly coherent while at the activation of "the non-dominant" hemisphere--a high range. 相似文献
4.
E V Rusinova 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1986,36(1):133-139
The dynamics of changes in intercentral relations of electrical activity of the sensorimotor and premotor zones of both hemispheres and the ventroposterolateral (VPL) nucleus of the left and right thalamus at formation of motor dominant under the action of the DC anode in the rabbit sensorimotor cortex was studied by the method of spectral-correlation analysis. It is shown that in the much less than dominant much greater than motor analyzer (the sensorimotor cortex and VPL) highly coherent connections of electrical processes are formed in the delta-range with conjugated lowering of biopotential connections between the structures of the motor analyzer of the much less than nondominant much greater than part of the brain. At the same time differently directed connections of electrical processes are formed between the structures of the motor analyzer, and between the premotor cortex and focus area. Thus, during formation of the much less than polarization much greater than dominant, a new structure of the intercentral relations of electrical processes is established not only in the much less than dominant much greater than but also in the other half of the brain. 相似文献
5.
Rusinova EV Roshchina GIa 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》2000,50(4):600-607
The electrical activity of the left and right sensorimotor cortex and left and right dorsal hippocampus (CA3 fields) was recorded during "animal hypnosis" in rabbits. The "animal hypnosis" produced asymmetry in the spectral power of the hippocampal electrical activity due to an increase in the power of delta 1, delta 2, and theta 1 components in the left-hippocampus and decrease in the spectral power in the same ranges in the right-hippocampus. Hemispheric asymmetry in the electrical activity during the "animal hypnosis" was also expressed in the indices of coherence between the sensorimotor cortex and hippocampus. EEG coherence between the left sensorimotor cortex and left hippocampus in the delta 1, theta 1, and theta 2 ranges was higher than that between the right-side structures. 相似文献
6.
E V Rusinova 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1989,39(2):301-308
The influence was studied of the stimulation of the CA3 field of the dorsal hippocampus on the course of motor polarization dominant created by the action of the direct current on the rabbit's cortical sensorimotor area. It is shown that hippocampus stimulation by 1 mA current (0.5 ms, 100 Hz, 0.2 s) against the background of the dominant optimum elicits its inhibition. It is manifested in depression of the motor "dominant" reaction of the forelimb to testing stimuli and in abolition of coherent connections of theta-range electrical activity of the sensorimotor cortex and CA3 field of the dorsal hippocampus. On the contrary, the hippocampus stimulation by a weak current (30-50 mcA, 0.5 ms, 30 Hz, 0.2 s) during optimum dominant reinforces it, eliciting a movement of the "dominant" limb. Against the background of an unstable dominant it provides for its activation and stabilization and recovers the dominant in the following days during its extinction. 相似文献
7.
Auditory cortical plasticity can be induced through various approaches. The medial geniculate body (MGB) of the auditory thalamus gates the ascending auditory inputs to the cortex. The thalamocortical system has been proposed to play a critical role in the responses of the auditory cortex (AC). In the present study, we investigated the cellular mechanism of the cortical activity, adopting an in vivo intracellular recording technique, recording from the primary auditory cortex (AI) while presenting an acoustic stimulus to the rat and electrically stimulating its MGB. We found that low-frequency stimuli enhanced the amplitudes of sound-evoked excitatory postsynaptic potentials (EPSPs) in AI neurons, whereas high-frequency stimuli depressed these auditory responses. The degree of this modulation depended on the intensities of the train stimuli as well as the intervals between the electrical stimulations and their paired sound stimulations. These findings may have implications regarding the basic mechanisms of MGB activation of auditory cortical plasticity and cortical signal processing. 相似文献
8.
E N Panakhova N A Gadzhieva F B Kulieva 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1984,34(1):115-123
In chronic experiments on waking rabbits, the foci of heightened excitability in the sensorimotor cortex and mesencephalic reticular formation affected in a similar way the background neuronal activity in the superior colliculi and that evoked by light stimuli. The effect was manifested in elimination of inhibitory pauses in the neuronal response to light stimulus and in a general increase of discharge frequency. Similarity of the cortical and reticular influences is due to their possible mediation by the same collicular interneurones participating in inhibitory pauses formation in the process of backward inhibition. Increased neuronal activity in the superior colliculi under the action of local foci in the sensorimotor cortex and mesencephalic reticular formation correlated with appearance of forelimb motor reaction to isolated light stimulus testifying to a formation of a functional connection between the visual and motor analyzers. Possible role of the superior colliculi in this process and their participation in the formation of a visually controlled reaction is discussed. 相似文献
9.
Functional organization of neurons in rabbit's sensorimotor cortex was studied before and within several days after formation of the rhythmical dominant focus. Functional reorganization of neurons in cortical microareas took place during actualization of the dominant. The number of functional interneuronal relations within neuronal pairs of a certain type could be increased in comparison with the control values and decreased within pairs of another type. As a result, the total percent of the interneuronal correlations in cortical microareas in the control animals and rabbits with the acting dominant was approximately equal. The total percent of correlations between neurons of the adjacent cortical areas during the actualization of the dominant was significantly higher than in the control due to increased number of correlations with participation of small and medium-sized neurons. A possibility of information circulation about the "stimulus image" in the closed chain of neurons was exemplified by the real micronetwork. The data suggest the reverberation of encoded information between adjacent microareas of the sensorimotor cortex within several days after application of the stimulus, which has formed the excitation focus. 相似文献
10.
R A Pavlygina Iu V Liubimova V I Davydov 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1991,41(1):122-130
By means of daily alimentary deprivation the dominant of hunger was created in rabbits. In response to acoustic stimuli summational swallowing and chewing movements appeared. Spectral analysis of the electrical brain activity showed the presence of primary dominant focus zone (lateral and ventromedial hypothalamus), characterized by an increase of spectrum power in delta-range while in the orbito-frontal, sensorimotor, parietal cerebral cortex, in the medial and lateral preoptic hypothalamic zones the power of biopotentials spectrum decreased within the whole analyzed frequency range. 相似文献
11.
Pavlygina RA Galashina AG Bogdanov AV 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》2002,52(4):508-510
A stationary excitation focus produced in the sensorimotor cortex of a rabbit by rhythmic electrodermal paw stimulation was manifested in the reaction to a testing sound stimulus earlier indifferent for the animal. Regardless of the stimulated paw (left or right), reactions to the testing stimuli appeared approximately in the equal percent of cases (70.7% and 71.5%, respectively). After a single-trial induction of the "animal hypnosis" state, it was difficult to produce the dominant focus by simulation of the left paw, whereas the results of the right-paw stimulation did not differ from those obtained during control stimulation. Consequently, the influence of hypnosis on defensive stationary excitation foci in different hemispheres was not the same. 相似文献
12.
G I Shul'gina A V Korinevski? 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1975,25(5):1011-1021
Experiments on alert non-immobilized rabbits revealed that electrical cutaneous stimulation of a limb, used as a reinforcing agent in elaboration of a conditioned reflex to photic flashes, weakened slow polyrhythmic oscillations of background EEG and late components of evoked potentials in the visual cortex to photic flashes. Against this background, the connection between slow potentials and spike activity in both the visual and sensorimotor cortical areas considerably diminished. During EEG activation, induced by the reinforcing stimulus, inhibitory pauses and post-inhibitory activation in the firing of the neocortical units weakened and protracted, ordered spike activity appeared. The data obtained are in agreement with the hypothesis that weakening of the recurrent inhibition system is one of the basic mechanisms in the action of the reinforcing stimulus in conditioning. 相似文献
13.
L I Chilingarian 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1999,49(3):385-399
Electrical activity of the frontal cortex, dorsal hippocampus, basolateral amygdala and lateral hypothalamus was recorded in eight dogs with chronically implanted electrodes. Mean values of the maxima of crosscorrelation function (MCCF) between electrical potentials in the theta, alpha and beta-2 ranges were used as a basis for assessment of conditions for interaction between these structures. Typological features of the higher nervous activity were assessed by the animal performance under conditions of free choice of the reinforcement mode of a conditioned stimulus: either high probable but of low alimentary quality or with low probability but more valuable. The mean MCCF values in the theta range were higher than in the other ranges. The brain structure which had the high MCCF in the theta-range, at least, with two of the structures under study was considered as "dominant". It was shown that hippocampus was the dominant structure for melancholic dogs, the frontal cortex was in phlegmatics. The hypothalamus was shown to be the "dominant structure" in both sanguine and choleric animals, but, for the most part, its activity was correlated with different structures. Thus, conditions for interaction between the frontal cortex, hippocampus, amygdala and hypothalamus seem to be an important factor, which determines typological features of the higher nervous activity of dogs. 相似文献
14.
The influence of nomifensine on bioelectrical activity of sensorimotor cortex, dorsal hippocamp and lateral hypothalamus in conscious rats in free behavior was studied. The pharmacological and EEG analysis of nomifensine action on EEG power spectra by Fourier technique was measured. It was established that nomifensine evoked an increase and stabilization of the dominant peak in EEG spectra in the left and right cortex and in the left hippocamp, while in the other ranges of frequency a decrease was observed. The effects on hypothalamus was opposite--EEG power spectra decreased in all the ranges. The authors conclude that nomifensine evokes higher level of wakefulness, vigilance of the animals. This is likely to underlie neurophysiological mechanisms of optimal behavior due to stimulants of CNS, including nomifensine. 相似文献
15.
Shul'gina GI 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》2000,50(3):473-481
A decrease in intensity and duration of short-latency reaction components of the sensorimotor and visual cortical neurons to specific stimuli (pain reinforcement and light flashes, respectively) was observed after the administration of NO-generating sodium nitrite (11 mg/kg, subcutaneously). Activation decrease in the visual cortex took place irrespective of biological significance of the light flashes, i.e., in case when this stimulus was a signal of defensive conditioning and in case when these flashes were applied with continuous light (a conditioned inhibitor). Sodium nitrite almost did not change the late activation of sensorimotor and visual neurons in response to pain reinforcement and disinhibitory action of the latter. The results confirm the viewpoint about different neurotransmitters in "specifically modal" and "non-specific" pathways to the neocortex during learning. 相似文献
16.
G Ia Roshchina 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1991,41(6):1186-1192
On rabbits in chronic experiment intercentral relations were studied of biopotentials of the sensorimotor cortical zone (blinking presentation in the cortex), VPM of the thalamus and motor nucleus of the oculomotor nerve at formation of blinking dominant created by serial stimulation of one eye by air jet. By the method of spectral-correlation analysis an increase was revealed of spectrum power and increase of COG of the potentials in delta-range in the structures connected with blinking function of the stimulated eye. At transition of the dominant focus to the inhibitory state and activation of the symmetrical centre of the other eye, in centers constellation of this induced focus a reconstruction of the electrical processes took place typical for the dominant. 相似文献
17.
Responses of medial geniculate body (MGB) neurons to pure tones and clicks were studied in acute experiments in immobilized cats, preliminary operations being performed under calypsol anaesthesia. MGB units were identified by their reactions to cortical zone AI and brachium of inferior colliculus stimulations. When tonal stimuli were applied relay neurons of pars principalis of MGB usually demonstrated either unimodal tuning curves with narrow frequency band or fragmental ones with several narrow bands. On-response with subsequent inhibition of the background activity or without such an inhibitory period was most frequent type of the reaction (66.6%) of relay MGB neurons to tonal stimulation. The group of relay neurons with the tonic type of reaction (9.1%) was classified for which the duration of tonic response depends on the duration of tonal stimulus. Change of the excitatory reaction to the inhibitory one when the characteristic tone frequency is changed by non-characteristic++ ones is supposed to be a mechanism supplying sharpness of tuning at relay MGB neurons. It is concluded that responses of acoustic cortical neurons to sound stimulation depend to a great extent on the pattern of impulsation that comes from MGB relay units. 相似文献
18.
Background and evoked neuronal activity in the cat sensorimotor cortex was recorded under a-chloralose anesthesia. Pairs of heterogeneous stimuli were applied, spaced at intervals of 0, 100, 200, 300, and 400 msec. A clicking sound, flashing light, and electroshock to the contralateral forepaw were used as stimuli. Partial or complete blockade of response to test stimuli presentations spaced 100–200 msec apart were observed when using stimulation of varying modality. The greatest test response was recorded at interstimulus intervals of 200–300 msec. Intracellular mechanisms of heterosensory interaction were investigated by applying the inhibitory transmitter antagonist picrotoxin microiontophoretically to the test cell to produce local attenuation of inhibitory effects. This substance also reduced the duration of blockage following the conditioning stimulus and the occurrence of peak level test response at a lower interstimulus interval than in the controls. Either a consistent increase in the number of spikes per response at one of the interstimulus intervals or a uniform reinforcement in unit response to several different interstimulus intervals were observed in a proportion of the cells. The contribution of intracortical inhibitory influences to the mechanisms of heterosensory interaction on neurons of the cat sensorimotor cortex is discussed in the light of our findings.A. A. Ukhtomskii Institute of Physiology, A. A. Zhdanov State University, Leningrad. Translated from Neirofiziologiya, Vol. 19, No. 2, pp. 147–156, March–April, 1987. 相似文献
19.
A B Kogan G A Kuraev I V Soboleva 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1976,26(1):59-64
The activity of single units in the focus of conditioned excitation was studied during defensive conditioning to direct electrical stimulation of the cat sensorimotor cortex. Reorganizations of spike activity set in during the period of reflex elaboration, were manifest in the increased number of excited neurones and those which respond both to the conditioned and unconditioned stimuli. In the course of elaboration, the inhibitory phase of unit responses to direct electrical stimulation of the sensorimotor cortex was reduced, while the frequency of background unit spike activity was enhanced. Acute extinction of the reflex restored the initial duration of the inhibitory phase and reduced the frequency of the background activity. 相似文献
20.
Umberto Castiello Bruno L. Giordano Chiara Begliomini Caterina Ansuini Massimo Grassi 《PloS one》2010,5(8)