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Mousumi Debnath Godavarthi B.K.S. Prasad Prakash S. Bisen 《Journal of chemical biology》2010,3(1):45-49
JOCB Bulletin
Welcome to this latest edition of the JoCB Bulletin containing items of information for the Chemical Biology Community 相似文献2.
《Journal of chemical biology》2009,2(3):153-160
JOCB Bulletin
Welcome to this latest edition of the JoCB Bulletin containing items of information for the Chemical Biology Community 相似文献3.
JOCB Bulletin
Welcome to this latest edition of the JoCB Bulletin containing items of information for the Chemical Biology Community 相似文献4.
JOCB Bulletin
Welcome to this second edition of the JoCB Bulletin containing items of information for the Chemical Biology Community 相似文献5.
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JOCB BULLETIN
Welcome to the JOCB Bulletin 相似文献7.
JOCB BULLETIN
Welcome to the JOCB Bulletin 相似文献8.
Gernot Renger 《Journal of chemical biology》2010,3(3):141-156
JOCB Bulletin
Welcome to the JOCB Bulletin 相似文献9.
Mark J. Eisenberg 《Journal of chemical biology》2010,3(2):89-100
JOCB Bulletin
Welcome to the JOCB Bulletin 相似文献10.
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The standpoint from which this article is written is that of development practitioners who work fairly continuously with community transformation processes, and with their peers in many disciplines who are trying to stimulate and support such processes. Drawing on three case examples, the authors put forward four lessons for an ecosystems approach to health development work. First, health and natural resource management professionals, and the technical solutions they create, cannot, by themselves, solve many of the problems communities face. To be effective, solutions have to address a complex set of variables that may be largely invisible to professionals from outside the communities. Creating a map of the human and natural systems within which a particular human health issue arises is often an important first step. Second, another reason why professionals cannot solve complex health challenges on their own is that, in the end, many of the solutions must be implemented by community people from the inside out. Therefore the “map” needs to include human dynamics and community capacity. Third, identifying and assessing the specific capacities that a community needs to address particular health determinants is therefore an important part of health development work. It is critical that community capacity assessment is not undertaken in the abstract, but rather in a way that links capacity assessment with real, ongoing work and through a participatory process that builds understanding and commitment within the community, and identifies clear pathways for future action. Finally, outside professionals working with a community contribute to its capacity to address critical health challenges, not only because of the technical knowledge and skills they bring, but also through the characteristics and attitudes they exhibit. It is therefore important that professionals build their own capacity to role model effective community practice. 相似文献
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《Bioscience, biotechnology, and biochemistry》2013,77(6):1135-1140
Recently, high-throughput screening (HTS) has become the mainstream technique for drug discovery. Compounds that are synthesized by combinatorial chemistry might be more suitable than natural products to apply to HTS, because the purification procedure is a drawback of using natural products. Nevertheless, natural products remain an extremely important source of drugs. To overcome the demerits of natural products, we are constructing the RIKEN Natural Products Depository (NPDepo) that is focused primarily on microbial metabolites. In this review, I describe (i) engineering pathways for biosynthetic gene clusters of microbial metabolites, (ii) construction of fraction libraries of microbial metabolites, and (iii) the development of a new screening system using a chemical array and a protein library produced by GLORIA. 相似文献
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《Biochemical Systematics and Ecology》2001,29(10):981-994
Chemical information conveyance between organisms has been well established for a wide range of organisms including protozoa, invertebrates, vertebrates and plant-parasitic plants. During the past 20 years, various studies have addressed whether chemical information conveyance also occurs between damaged and undamaged plants and many interesting pieces of evidence have been presented. To date, this research field has been restricted to the question whether and how plants (in general) are involved in plant-to-plant communication. However, apart from mechanistic questions, evolutionary questions should be addressed asking why plants do (or do not) exploit their neighbour's information and whether their strategy is affected by e.g. environmental conditions or previous experience. Recent progress in the field of chemical information conveyance between damaged and undamaged plants warrants an intensified study of this exciting topic in chemical ecology. 相似文献