共查询到20条相似文献,搜索用时 31 毫秒
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P. L. Newland 《Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology》1998,183(3):313-324
Taste receptors, or basiconic sensilla, are distributed over the legs of the locust and respond to direct contact with chemical
stimulants. The same chemosensory neurones that responded to contact with salt solutions also responded to particular acidic
odours. Odours of food and other chemicals had no effect on the chemosensory neurones. In locusts free to move, an acid odour
presented to the tarsus of a hind leg evoked a rapid avoidance movement in which the tarsus was levated, the tibia flexed
and the femur levated. Intracellular recordings from motor neurones that innervate muscles of the hind leg showed that when
an acid odour was directed towards basiconic sensilla on the leg there was a reciprocal activation of antagonistic motor pools
that move the leg segments about each joint. Thus an extensor tibiae motor neurone was inhibited while a flexor tibiae motor
neurone was excited, and the tarsal depressor and retractor unguis motor neurones were inhibited while the tarsal levator
motor neurone was excited. This method of odour stimulation of taste receptors generates less adaptation than direct contact
with chemicals, and therefore represents an ideal method for stimulating taste receptors for further studies on the central
pathways processing taste signals.
Accepted: 2 June 1998 相似文献
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D S McQueen 《Quarterly journal of experimental physiology and cognate medical sciences》1978,63(2):171-178
The present electrophysiological study shows that methacholine (MCh), generally regarded as a muscarinic agonist, stimulates the carotid chemoreceptors in pentobarbitone anaesthetized cats. The response consisted of a primary increase in discharge, attributable to nicotinic actions of MCh since it was unaffected by atropine but abolished by mecamylamine, and a delayed secondary increase in discharge, due mainly to bronchoconstriction evoked by MCh. Physostigmine caused similar potentiation of responses to acetylcholine and MCh which implies that acetylcholinesterase is located close to the site(s) at which the drugs act to stimulate chemoreceptor activity. The findings are in agreement with the general principle that chemosensory activity is increased by nicotinic agonists but not by muscarinic agonists. 相似文献
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Donnelly D. F.; Nolan W. F.; Smith E. J.; Dutton R. E. 《Journal of applied physiology》1985,59(5):1566-1570
The carotid body impulse generator has been previously characterized as a Poisson-type random process. We examined the validity of this characterization by analyzing sinus nerve spike trains for interspike interval dependency. Fifteen single chemoreceptive afferents were recorded in vivo under hypoxic-hypercapnic conditions, and approximately 1,000 consecutive interspike intervals for each fiber were timed and analyzed for serial dependence. The same set of intervals placed in shuffled order served as a control series without serial dependence. The original spike interval trains showed significantly negative first-order serial correlation coefficients and less variability in joint interval distributions than did the shuffled interval trains. These results suggest that the chemoreceptor afferent train is not random and may reflect a negative feedback system operating within the carotid body that limits variation about a mean frequency. 相似文献
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