Respiratory illness and home environment of ethnic groups

Factors contributing to differences in the prevalences of respiratory symptoms and diseases among ethnic groups were studied in primary schoolchildren living in 20 inner city areas of England in 1983. The raised prevalences of respiratory symptoms in these groups were compared with results from a national representative sample of children studied in 1982. Data on age, sex, respiratory illness, and social and environmental variables were obtained by questionnaire for 4815 children living in inner cities. The children were classified as white, Afro-Caribbean, Urdu, Gujarati, Punjabi, other Asian, or “other.” Significant differences in the prevalence of respiratory conditions were found among the ethnic groups after allowance was made for the effects of interfering variables. Except for asthma all conditions were most prevalent in Afro-Caribbeans and whites. In these two ethnic groups respiratory illness was significantly associated with belonging to a one parent family and the combined use of gas cookers and paraffin heaters at home.Respiratory illness was found to vary in prevalence among ethnic groups but may be perceived differently by different groups. Further studies, measuring lung function, are necessary.     

Stereotypes of mental illness: A comparison with ethnic stereotypes

This paper draws on empirical and theoretical studies to argue that popular and professional conceptions of mental illness share specific traits with ethnic stereotypes: (1) they are exaggerated and serve to erect a qualitative boundary where none objectively exists: (2) they are maintained through selective perception, rationalization, and sanctions; (3) they help to erect the thresholds, i.e., the criteria, for crossing or recrossing the boundary; (4) they serve to define relations, including those of power, between groups; (5) because they perform these important cognitive and conative functions, they persist despite a flow of personnel across them and despite repeated demonstrations of their inaccuracy. They cannot be expected to change until the actual relations between groups change.     

Mental illness in inner London.

From the perspective of general practice, hospital data indicating that the prevalence of mental illness is much higher in inner London than elsewhere in Britain may be misleading. A study in five inner London practices found morbidity patterns for mental disorder similar to those recorded in a national survey.     

Quantitative alleles of CR1: coding sequence analysis and comparison of haplotypes in two ethnic groups.

The quantitative expression of complement receptor type 1 (CR1) on erythrocytes is regulated by two CR1 alleles that differ in having genomic HindIII fragments of either 7.4 or 6.9 kb and that determine high (H allele) or low (L allele) CR1 expression, respectively, across a 10-fold range. To investigate whether the product of the L allele may contain amino acid substitutions that make it more susceptible to proteolysis, cDNA sequence spanning the CR1 coding region was analyzed in two donors who were homozygous for the H and L alleles and differed by 7-fold in their mean numbers of CR1 per erythrocyte. Sequence differences were detected at 10 nucleotide positions, including 6 that would cause amino acid substitutions. The HindIII RFLP and 3 of the latter 6 sites were analyzed in genomic DNA of 85 Caucasians and 75 African Americans; sites encoding the other amino acid substitutions were analyzed less extensively. Two major haplotypes defined prototypic H and L alleles in both ethnic groups, suggesting that these alleles existed before the African and European populations diverged. Decreased erythrocyte CR1 expression is associated with impaired clearance of immune complexes from blood. Persistence of the L allele in all populations that have been analyzed may suggest a compensatory survival advantage, perhaps related to malaria or another infectious disease.     

Familial systemic lupus erythematosus: a comparison of clinical manifestations and antibody presentation in three ethnic groups.

The serologic and clinical features of patients from pedigrees multiplex for systemic lupus erythematosus (SLE) were evaluated among three ethnic groups: Hispanics, African-Americans and European-Americans. Data were obtained from a registry of 123 pedigrees, composed of 4 Hispanic, 40 African-American and 79 European-American pedigrees. All patients met at least four criteria for the diagnosis of SLE per the American College of Rheumatology. Clinical information was obtained through review of the medical records and questionnaires completed by the participants. Ethnicity by self-identification was found to be an important factor influencing the prevalence of serologic results and clinical features. Anti-nRNP occurred more frequently in African-Americans (45.7%) than in European-Americans (7.5%) or Hispanics (0%) (p<0.0000001), as did anti-Sm (18.5% vs 1.6% and 0%, respectively) (p<0.000001). Malar rash, photosensitivity and oral ulcers were most frequent in the Hispanic population while proteinuria and leukopenia predominated in the African-American population. Arthritis and lymphopenia were present in a similar proportion in all ethnic groups. These results show that many of the ethnic differences known for isolated cases of SLE are also present in familial cases of SLE.     

Genetic variability in two Brazilian ethnic groups: A comparison of mitochondrial and protein data

Sequence data from the first hypervariable segment of the mitochondrial DNA control region of 124 subjects belonging to three African-Brazilian and three Brazilian Indian populations were compared with information related to 12 protein genetic loci from 601 persons living in the same localities. There is high diversity among the mtDNA sites, and the most variable in one ethnic group are not the most variable in the other. No differences in gene diversity between populations within ethnic groups were observed, but the Indians showed a reduced variability. Much more interpopulation variation was observed in the mtDNA data than in the protein set. The relationships obtained for the six populations, however, are the same regardless whether mtDNA or protein loci are considered. African-Brazilians from Porto Alegre and Salvador, situated 3,000 km apart, are more similar to each other than both are to Paredão, despite the geographical proximity between Porto Alegre and Paredão, which are just 50 km apart. The tree topology in relation to the three Indians groups, on the other hand, is that expected when languages, culture, and geography are considered. Am J Phys Anthropol 103:147–156, 1997. © 1997 Wiley-Liss, Inc.     

Cognitive and educational attainment in different ethnic groups.

The educational attainment of over 2000 children aged 7-15 years from six different ethnic groups was assessed. Children of Pakistani and of Bangladeshi origin tended to obtain the lowest mean scores on all tests, often well below those of West Indian children, who tended to perform as well as Indian children and often no worse than the indigenous majority. There were few signs of any reliable trends over age. Differences were more pronounced on tests of reading and vocabulary than on tests of mathematics but, on tests of non-verbal reasoning, most ethnic minorities also obtained low scores. Many of these differences were associated with differences in social and family circumstances.     

Health of Hmong in Thailand: Risk factors,morbidity and mortality in comparison with other ethnic groups

Demographic and health conditions among Hmong in Thailand were examined in comparison with other ethnic groups which closely resemble the ethnic origins of Southeast Asian refugees in the U.S. Thailand Hmong have very large extended family households, very high birth rates, low use of contraception, very young age at first marriage, and, compared with other highland minorities, relatively low infant and crude mortality rates. Hmong use of tobacco and alcohol and other stimulants is lower than other ethnic groups, and is much more frequent among men than among women. Opium was used by 15% of the men in the surveyed village, lower than among another highland group, but higher than in surveyed lowland villages. Fewer illnesses were reported by Hmong in the 7 days prior to survey than in other rural groups. Relatively low Hmong morbidity and mortality as compared with other highland ethnic groups may be associated with low use of tobacco and alcohol, and with the sharing of child care responsibilities within the large Hmong extended family households]This is the revised version of a paper presented at the Psychosocial Workshop of the Population Association of America Annual Meeting, Boston, 27 March 1985. Research was supported by National Science Foundation grant BNS 7914093, and by the East-West Center. Opinions expressed are those of the author.     

Differences in rate of uptake of immunisation among ethnic groups.

In the Bradford health district ethnic origin is associated with appreciable differences in morbidity and mortality. In view of these differences a study was undertaken to determine whether there were differences among the ethnic groups in utilisation of the National Health Service, as reflected in the rate of uptake of immunisation, which is offered to all children. Significant differences were found between the British group and some other ethnic groups--notably Pakistani, Indian, and half Negro groups. The rate of uptake of immunisation was nearer the optimum in the Indian group than in the British group. The most unsatisfactory rate of uptake of immunisation overall was found in the half Negro group. No clear explanation of the differences has been shown, they are likely to be due to various factors in the National Health Service and in the community.     

Chosen peoples: Why ethnic groups survive*

The persistence of ethnic communities is a neglected area of research. The study of ethnies over long time‐spans requires comparison of different patterns of ethnic survival, in terms of symbols and myths of ethnic election. Such myths can be found in the ancient Near East, in Judea, Greece, Armenia, Persia, as well as Byzantium, Russia and Western Europe, mobilizing and inspiring ethnic survival. Four main patterns of ethnic survival are outlined: imperial‐dynastic, communal‐demotic, emigrant‐colonist and diaspora‐restoration. In each case, modern nationalism reinforces and politicizes the old myths of ethnic election and its forms and intensity can be explained in terms of these patterns of ethnic survival.     

Glutamate-pyruvate transaminase subtypes in Singapore ethnic groups

Autopsy liver samples from 244 Chinese, 119 Malays and 136 Indians were screened for glutamate-pyruvate transaminase (GPT) subtypes by starch-gel electrophoresis and isoelectric focusing at pH 5-7. Altogether, ten phenotypes controlled by four alleles (GPT1, GPT2A, GPT2B and GPT3) were identified. There was no significant difference in the frequency of GPT alleles between the ethnic groups. The distribution of GPT types was in agreement with the Hardy-Weinberg equilibrium in all the ethnic groups.