Bioethics,politics and the moral economy of human embryonic stem cell science: the case of the European Union's Sixth Framework Programme

Public communication of science is still largely conceptualized within a ‘transfer’ paradigm that describes it as a displacement of results and ideas from the specialists to the lay public, problematizing the public, the media, (sometimes) science, but very rarely the notion of communication itself. This paper is a preliminary attempt to see if the discourse about genes and the genome can help us to problematize the concept of communication in relation to science, rethink our models of public communication of science and, more generally, the metaphors we employ to describe communication. It is suggested that the relationship between science and the public could be understood better by viewing communication through metaphors drawn from contemporary biology, e.g. as ‘cross‐talk’ between the specialist and public discourse or as a ‘double helix’ coupling the two dimensions under certain conditions.     

Environmental indices and the politics of the Conservation Reserve Program

Environmental indicators can be used to target public programs to provide a variety of benefits. Social scientists, physical scientists, and politicians have roles in developing indicators that reflect the demands of diverse interest groups. We review the US Department of Agriculture’s Conservation Reserve Program (CRP), the largest agricultural conservation program the United States, to determine how a set of environmental indicators were developed and used, and assess results of their application. The use of such indicators has helped the CRP increase and broaden the program’s environmental benefits beyond erosion reduction, which was the primary focus of early program efforts, to meet other demands. This case study provides an example about how integration and assessment for the purpose of managing public resources requires more than natural science disciplines. Social science can help explain how public values influence what information is collected and how it is interpreted. Examples are given to show how the indices used for the CRP integrated science, politics and social values. In the end, the environmental benefits index (EBI) used to target US$ 20 billion of CRP funds reflects compromises made between science and policy considerations. It is our intention that studying this index will yield ideas and understanding from the natural science community that develops ecosystem indices about how to better plug in to programs in the future.     

From Claude Bernard to the Batcave and beyond: using Batman as a hook for physiology education

Communicating physiology to the general public and popularizing science can be tremendously rewarding activities. Providing relevant and compelling points of linkage, however, between the scientific experiences and the interests of the general public can be challenging. One avenue for popularizing science is to link scientific concepts to images, personalities, and icons in popular culture. Currently, comic book superhero movies and television shows are extremely popular, and Batman was used as the vehicle for popularizing concepts of exercise science, neuroscience, and physiology in my recent book, Becoming Batman: the Possibility of a Superhero. The objective of this book was to bring scientific understanding to the broader public by using the physical image and impression everyone has of Batman and his abilities and then connecting this to the underlying science. The objective of this article is to share some of the details of the process and the positive and negative outcomes of using such an approach with other academics who may be interested in similar activities. It is my goal that by sharing this experience I may stimulate like-minded readers to initiate their own similar projects and to also be emboldened to try and integrate popular culture touchstones in their own teaching practice.     

Cowboys and Aliens: Body Techniques and Audience Reception in Malaita,Solomon Islands

Based on ethnographic fieldwork among the Lau of Malaita Province, Solomon Islands, this article revisits the “imperial cowboy problem” through an anthropology of technology approach. It examines audience preference for Westerns, or “cowboy movies,” and their rejection of science fiction, or “new technology movies.” Non-verbal, visual communication, material cultures and body techniques are shown to be particularly significant for how unintended audiences engage with foreign visual media, given their own sociocultural context.     

Robert Chambers and Thomas Henry Huxley, Science Correspondents: The Popularization and Dissemination of Nineteenth Century Natural Science

Robert Chambers and Thomas Henry Huxley helped popularize science by writing for general interest publications when science was becoming increasingly professionalized. A non-professional, Chambers used his family-owned Chambers' Edinburgh Journal to report on scientific discoveries, giving his audience access to ideas that were only available to scientists who regularly attended professional meetings or read published transactions of such forums. He had no formal training in the sciences and little interest in advancing the professional status of scientists; his course of action was determined by his disability and interest in scientific phenomena. His skillful reporting enabled readers to learn how the ideas that flowed from scientific innovation affected their lives, and his series of article in the Journal presenting his rudimentary ideas on evolution, served as a prelude to his important popular work, Vestiges of the Natural History of Creation. Huxley, an example of the new professional class of scientists, defended science and evolution from attacks by religious spokesmen and other opponents of evolution, informing the British public about science through his lectures and articles in such publications as Nineteenth Century. He understood that by popularizing scientific information, he could effectively challenge the old Tory establishment -- with its orthodox religious and political views -- and promote the ideas of the new class of professional scientists. In attempting to transform British society, he frequently came in conflict with theologians and others on issues in which science and religion seemed to contradict each other but refused to discuss matters of science with non-professionals like Chambers, whose popular writing struck a more resonant chord with working class readers. This revised version was published online in July 2006 with corrections to the Cover Date.     

What are genes “for” or where are traits “from”? What is the question?

For at least a century it has been known that multiple factors play a role in the development of complex traits, and yet the notion that there are genes “for” such traits, which traces back to Mendel, is still widespread. In this paper, we illustrate how the Mendelian model has tacitly encouraged the idea that we can explain complexity by reducing it to enumerable genes. By this approach many genes associated with simple as well as complex traits have been identified. But the genetic architecture of biological traits, or how they are made, remains largely unknown. In essence, this reflects the tension between reductionism as the current “modus operandi” of science, and the emerging knowledge of the nature of complex traits. Recent interest in systems biology as a unifying approach indicates a reawakened acceptance of the complexity of complex traits, though the temptation is to replace “gene for” thinking by comparably reductionistic “network for” concepts. Both approaches implicitly mix concepts of variants and invariants in genetics. Even the basic question is unclear: what does one need to know to “understand” the genetic basis of complex traits? New operational ideas about how to deal with biological complexity are needed.     

“反向免疫学”与免疫功能基因的发现

人类基因组测序的结束为生命科学领域展开了全新的一章.尽管已经得到了人类基因组的序列,但是隐藏在DNA序列中的功能基因,它们之间的相互作用以及对整个机体的意义大部分有待发掘.近些年来形成的“反向生物学”为免疫功能基因的发现、功能的研究及其应用价值提供了一套全新的技术与思路.     

Science and the Concept of Evolution: From the Big Bang to the Origin and Evolution of Life

The common thread of evolution runs through all science disciplines, and the concept of evolution enables students to better understand the nature of the universe and our origins. “Science and the Concept of Evolution” is one of two interdisciplinary science Core courses taken by Dowling College undergraduates as part of their General Education requirements. The course examines basic principles and methods of science by following the concept of evolution from the big bang to the origin and evolution of life. Case studies of leading scientists illustrate how their ideas developed and contributed to the evolution of our understanding of the world. Evidences for physical, chemical, and biological evolution are explored, and students learn to view the evolution of matter and of ideas as a natural process of change over space and time.     

Ideas about heredity, genetics, and 'medical genetics' in Britain, 1900-1982

The aim of this paper is to understand how evolving ideas about heredity and genetics influenced new medical interests and practices and, eventually, the formation of 'medical genetics' as a medical specialism in Britain. I begin the paper by highlighting the social and institutional changes through which these ideas passed. I argue that, with time, there was a decisive convergence in thought that combined ideas about the familial aspects of heredity and the health needs of populations with an omnibus 'genetic' approach to health and illness that focused on the structures and activities of chromosomes and genes in individuals. I show how this convergence in thought was spurred on, first, by innovations in genetic science and technology in the years after 1960, and, second, by negotiated protocols and standards of medical practice worked out by bodies such as the relevant royal colleges, the linked associations and societies for medical professionals, affected training and research authorities, and the state. The notion of 'medical genetics' in Britain consequently gained a semblance of unanimity over its basic reference points and arrived at a meaning directly tributary to current acceptance of the term in the context of a medical specialism.     

Improving the public understanding of science: New initiatives

The United States may be on the brink of losing its global edge in science. Many American students are underprepared for and uninterested in the scientific and technical careers they may be asked to take on. Furthermore, these students, their teachers, and the broader public lack basic understandings of what science is and how it works, which may negatively impact their ability to make reasoned and informed decisions about science-related issues. We describe two unique and recently developed projects designed to help tackle these problems by improving public understanding of and interest in science. The Coalition on the Public Understanding of Science is a grassroots effort to lower the barriers between the scientific community and the public. It aims to inspire broad appreciation of science, inform the public about the nature and process of science, and make science accessible to everyone. Understanding Science is a web-based project that aims to improve teacher understanding of the nature of the scientific enterprise, to provide resources that encourage and enable kindergarten through undergraduate (K-16) teachers to reinforce the nature of science throughout their teaching, and to serve as a clear and accessible reference that accurately portrays the scientific endeavor. The botanical and broader scientific communities are invited to participate in these efforts.     

Molecular Gastronomy: A Food Fad or an Interface for Science-based Cooking?

A review is given over the field of molecular gastronomy and its relation to science and cooking. We begin with a brief history of the field of molecular gastronomy, the definition of the term itself, and the current controversy surrounding this term. We then highlight the distinction between molecular gastronomy and science-based cooking, and we discuss both the similarities and the distinctions between science and cooking. In particular, we highlight the fact that the kitchen serves as an ideal place to foster interactions between scientists and chefs that lead to benefits for the general public in the form of novel and high-quality foods. On the one hand, it can facilitate the implementation of new ideas and recipes in restaurants. On the other hand, it challenges scientists to apply their fundamental scientific understanding to the complexities of cooking, and it challenges them to expand the scientific understanding of many chemical and physical mechanisms beyond the common mass-produced food products. In addition, molecular gastronomy forms an ideal base to educate the general public about the basic principles of science and cooking and how they can be utilized to improve the awareness of the role of food and nutrition for the quality of life.     

A priority paper for the societal and ethical aspects of synthetic biology

As synthetic biology develops into a promising science and engineering field, we need to have clear ideas and priorities regarding its safety, security, ethical and public dialogue implications. Based on an extensive literature search, interviews with scientists, social scientists, a 4 week long public e-forum, and consultation with several stakeholders from science, industry and civil society organisations, we compiled a list of priority topics regarding societal issues of synthetic biology for the years ahead. The points presented here are intended to encourage all stakeholders to engage in the prioritisation of these issues and to participate in a continuous dialogue, with the ultimate goal of providing a basis for a multi-stakeholder governance in synthetic biology. Here we show possible ways to solve the challenges to synthetic biology in the field of safety, security, ethics and the science–public interface.     

FOUNDING A NEW SCIENCE: MIND GENOMICS

We present in this article our vision for a new science, modeled on the emerging science of genomics and the technology of informatics. Our goal in this new science is to better understand how people react to ideas in a formal and structured way, using the principles of stimulus–response (from experimental psychology), conjoint analysis (from consumer research and statistics), Internet‐based testing (from marketing research) and multiple tests to identify patterns of mind‐sets (patterned after genomics). We show how this formal approach can then be used to construct new, innovative ideas in business. We demonstrate the approach using the development of new ideas for an electronic color palette for cosmetic products to be used by consumers.     

Attitudes to biotechnology: estimating the opinions of a better-informed public

Public familiarity with basic scientific concepts and principles has been proposed as essential for effective democratic decision-making (Miller, 1998). Empirical research, however, finds that public 'scientific literacy' is generally low, falling well short of what normative criteria would consider 'acceptable.' This has prompted calls to better engage, educate and inform the public on scientific matters, with the additional, usually implicit assumption that a knowledgeable citizenry should express more supportive and favourable attitudes toward science. Research investigating the notion that 'to know science is to love it' has provided only weak empirical support and has itself been criticised for representing science and technology as a unified and homogenous entity. In practice, it is argued, how knowledge impacts on the favourability of attitudes will depend on a multiplicity of actors, not the least of which is the particular area of science in question and the technologies to which it gives rise (Evans & Durant, 1992). This article uses a new method for examining the knowledge-attitude nexus on a prominent area of 21st century science--biotechnology. The idea that greater scientific knowledge can engender change in the favourability of attitudes toward specific areas of science is investigated using data from the 2000 British Social Attitudes Survey and the 1999 Wellcome Consultative Panel on Gene Therapy. Together the surveys measure public opinion on particular applications of genetic technologies, including gene therapy and the use of genetic data, as well as more general attitudes towards genetic research. We focus our analysis on how two different measures of knowledge impact on these attitudes; one a more general measure of scientific knowledge, the other relating specifically to knowledge of modern genetic science. We investigate what impact these knowledge domains have on attitudes toward biotechnology using a regression-based modelling technique (Bartels, 1996; Althaus, 1998; Sturgis, 2003). Controlling for a range of socio-demographic characteristics, we provide estimates of what collective and individual opinion would look like if everyone were as knowledgeable as the currently best-informed members of the general public on the knowledge domains in question. Our findings demonstrate that scientific knowledge does appear to have an important role in determining individual and group attitudes to genetic science. However, we find no support for a simple 'deficit model' of public understanding, as the nature of the relationship itself depends on the application of biotechnology in question and the social location of the individual.     

Negotiating the Therapeutic Gap: Prenatal Diagnostics and Termination of Pregnancy in Sri Lanka

In Sri Lanka, termination of pregnancy, other than in extreme circumstances, is strictly illegal. Among the public and large sections of the medical community there is widespread support for some degree of liberalization of the law, particularly where this relates to serious genetic conditions which can be identified prenatally. Tension emerges out of a publicly maintained conservatism on issues of abortion on the one hand and a growing disconnection from unregulated practices of termination in the private sector on the other. Social science approaches have much to contribute when understanding the ‘therapeutic gap’ that opens up and, in particular, the way that local ideas of fate, destiny and how suffering might be ameliorated become blended with the predictive power of genetic testing.     

On being a (modern) scientist: risks of public engagement in the UK interspecies embryo debate

In 2006, a small group of UK academic scientists made headlines when they proposed the creation of interspecies embryos – mixing human and animal genetic material. A public campaign was fought to mobilize support for the research. Drawing on interviews with the key scientists involved, this paper argues that engaging the public through communicating their ideas via the media can result in tensions between the necessity of, and inherent dangers in, scientists campaigning on controversial issues. Some scientists believed that communicating science had damaged their professional standing in the eyes of their peers, who, in turn, policed the boundaries around what they believed constituted a “good” scientist. Tensions between promoting “science” versus promotion of the “scientist”; engaging the public versus publishing peer-reviewed articles and winning grants; and building expectations versus overhyping the science reveal the difficult choices scientists in the modern world have to make over the potential gains and risks of communicating science. We conclude that although scientists' participation in public debates is often encouraged, the rewards of such engagement remain. Moreover, this participation can detrimentally affect scientists' careers.     

Public discourses of stem cell science in Singapore (1997–2010)

In most industrialized countries, policy debates around stem cell science manifest in public discourse. Assuming that a functioning public sphere exists where matters of science policy can be discussed, examination of these discourses can help provide an understanding of how science policies evolve. The aim of this paper is to provide a preliminary analysis of how the public discourses around stem cell science have developed in Singapore. Using a theoretical model of “focused discourse,” our analysis indicates that there have been five distinct phases, marked by discernible shifts that reflect important changes in how biomedical science is funded in Singapore. While our results are preliminary, we argue that public discourses around science policies do exist in Singapore but are limited by a lack of diversity that would be expected in a more heterogeneous public sphere.     

Defining the spectrum of genome policy

Many achievements in the genome sciences have been facilitated by policies that have prioritized genome research, secured funding and raised public and health-professional awareness. Such policies should address ethical, legal and social concerns, and are as important to the scientific and commercial development of the field as the science itself. On occasion, policy issues take precedence over science, particularly when impasses are encountered or when public health or money is at stake. Here we discuss the spectrum of current issues and debates in genome policy, and how to actively engage all affected stakeholders to promote effective policy making.     

Falling giants and the rise of gene editing: ethics,private interests and the public good

This paper considers the tensions created in genomic research by public and private for-profit ideals. Our intent is to strengthen the public good at a time when doing science is strongly motivated by market possibilities and opportunities. Focusing on the emergence of gene editing, and in particular CRISPR, we consider how commercialisation encourages hype and hope—a sense that only promise and idealism can achieve progress. At this rate, genomic research reinforces structures that promote, above all else, private interests, but that may attenuate conditions for the public good of science. In the first part, we situate genomics using the aphorism that ‘on the shoulders of giants we see farther’; these giants are infrastructures and research cultures rather than individual ‘heroes’ of science. In this respect, private initiatives are not the only pivot for successful discovery, and indeed, fascination in those could impinge upon the fundamental role of public-supported discovery. To redress these circumstances, we define the extent to which progress presupposes research strategies that are for the public good. In the second part, we use a ‘falling giant’ narrative to illustrate the risks of over-indulging for-profit initiatives. We therefore offer a counterpoint to commercialised science, using three identifiable ‘giants’—scientists, publics and cultures—to illustrate how the public good contributes to genomic discovery.     

China Art by Phone: Mobile Movies

Jia ZhangKe's film Platform gives crystalline shape to a generation in a group of youth gathered around a tape-recorder in Fenyang city. The tape itself had come from Guangzhou and before that, presumably, from across the border with Hong Kong. Perhaps a Cantonese filtering, a local expression of Western and brand-name product that, viewed positively, marks the largest and most sweeping educational drive in China's history, the distribution and assimilation of fashion, DVDs, CDs, video, and design. This article seeks to know empirically the conditions that lay the groundwork for this educational drive, focusing on social transformation and the impact of digital technologies on theory, approach, practice, consumption. Clearly, mobility is important in this process of social transformation. Platform gives us images of the mobility of people, things, and ideas. This article also looks at the effects of the transport of people, things, and ideas and explores the cultural dimensions of social transformation. The article asks: What is mobility for artists and media producers? What are the urbanistic interconnections that emerge from an engagement with public space? These questions are explored around the social and cultural terrain of the mobile phone.

The article considers the virtual public space of the mobile telephone now opening to cultural producers and consumers. In what way does the mobile telephone, as an instrument for dialogue, a marketing device, and a promotional tool, affect our perception of public space? This article examines several initiatives that bring the mobile phone and cultural production together. One of these is titled “Focus: This Moment,” a program of eight short films by eight contemporary Chinese film directors made for mobile phone and Internet distribution. Another is “Connect to Art,” initiated by Nokia in September 2004 in Helsinki, continued in Monaco in December 2004, and then furthered again in Shanghai in May 2006 with the unveiling of four works by Chinese contemporary artists: Ai Weiwei, Yang Fudong, Zhang Peili, and Feng Mengbo. The article considers how mobile phone movies modify and enrich our understanding of cinema. This is thus an enquiry into the impact of digital technology on the mature film industry. Furthermore, the article asks how public space is enfolded in multiple contextual discourses that create the mobility and interface of the mobile phone.