ISCB Ebola Award for Important Future Research on the Computational Biology of Ebola Virus

Speed is of the essence in combating Ebola; thus, computational approaches should form a significant component of Ebola research. As for the development of any modern drug, computational biology is uniquely positioned to contribute through comparative analysis of the genome sequences of Ebola strains as well as 3-D protein modeling. Other computational approaches to Ebola may include large-scale docking studies of Ebola proteins with human proteins and with small-molecule libraries, computational modeling of the spread of the virus, computational mining of the Ebola literature, and creation of a curated Ebola database. Taken together, such computational efforts could significantly accelerate traditional scientific approaches. In recognition of the need for important and immediate solutions from the field of computational biology against Ebola, the International Society for Computational Biology (ISCB) announces a prize for an important computational advance in fighting the Ebola virus. ISCB will confer the ISCB Fight against Ebola Award, along with a prize of US$2,000, at its July 2016 annual meeting (ISCB Intelligent Systems for Molecular Biology [ISMB] 2016, Orlando, Florida).     

Computational Biology of Olfactory Receptors

Olfactory receptors, in addition to being involved in first step of the physiological processes that leads to olfaction, occupy an important place in mammalian genomes. ORs constitute super families in these genomes. Elucidating ol-factory receptor function at a molecular level can be aided by a computationally derived structure and an understanding of its interactions with odor molecules. Experimental functional analyses of olfactory receptors in conjunction with computational studies serve to validate findings and generate hypotheses. We present here a review of the research efforts in: creating computational models of olfactory receptors, identifying binding strategies for these receptors with odorant molecules, performing medium to long range simulation studies of odor ligands in the receptor binding region, and identifying amino acid positions within the receptor that are responsible for ligand-binding and olfactory receptor activation. Written as a primer and a teaching tool, this review will help researchers extend the methodologies described herein to other GPCRs.     

Computational Molecular Biology(CMB)

正Computational Molecular Biology(ISSN 1927-5587)is an open access,peer reviewed journal published online by Bio Publisher.The Journal is publishing all the latest and outstanding research articles,letters,methods,and reviews in all areas of Computational Molecular Biology,covering new discoveries in molecular biology,from genes to genomes,using statistical,mathematical,and computational methods as well as new     

Computational Molecular Biology(CMB)

正Computational Molecular Biology(ISSN 1927-5587)is an open access,peer reviewed journal published online by Bio Publisher.The Journal is publishing all the latest and outstanding research articles,letters,methods,and reviews in all areas of Computational Molecular Biology,covering new discoveries in molecular biology,from genes to genomes,using statistical,mathematical,and computational methods as well as new     

Computational Molecular Biology(CMB)

正Computational Molecular Biology(ISSN 1927-5587)is an open access,peer reviewed journal published online by Bio Publisher.The Journal is publishing all the latest and outstanding research articles,letters,methods,and reviews in all areas of Computational Molecular Biology,covering new discoveries in molecular biology,from genes to     

Computational Molecular Biology(CMB)

正Computational Molecular Biology(ISSN 1927-5587)is an open access,peer reviewed journal published online by Bio Publisher.The Journal is publishing all the latest and outstanding research articles,letters,methods,and reviews in all areas of Computational Molecular Biology,covering new discoveries in molecular biology,from genes to     

Computational Molecular Biology(CMB)

正Computational Molecular Biology(ISSN 1927-5587)is an open access,peer reviewed journal published online by Bio Publisher.The Journal is publishing all the latest and outstanding research articles,letters,methods,and reviews in all areas of Computational Molecular Biology,covering new discoveries in molecular biology,from genes to     

Computational Molecular Biology(CMB)

<正>Computational Molecular Biology(ISSN 1927-5587)is an open access,peer reviewed journal published online by Bio Publisher.The Journal is publishing all the latest and outstanding research articles,letters,methods,and reviews in all areas of Computational Molecular Biology,covering new discoveries in molecular biology,from genes to genomes,     

Computational Biology and Bioinformatics in Nigeria

Over the past few decades, major advances in the field of molecular biology, coupled with advances in genomic technologies, have led to an explosive growth in the biological data generated by the scientific community. The critical need to process and analyze such a deluge of data and turn it into useful knowledge has caused bioinformatics to gain prominence and importance. Bioinformatics is an interdisciplinary research area that applies techniques, methodologies, and tools in computer and information science to solve biological problems. In Nigeria, bioinformatics has recently played a vital role in the advancement of biological sciences. As a developing country, the importance of bioinformatics is rapidly gaining acceptance, and bioinformatics groups comprised of biologists, computer scientists, and computer engineers are being constituted at Nigerian universities and research institutes. In this article, we present an overview of bioinformatics education and research in Nigeria. We also discuss professional societies and academic and research institutions that play central roles in advancing the discipline in Nigeria. Finally, we propose strategies that can bolster bioinformatics education and support from policy makers in Nigeria, with potential positive implications for other developing countries.     

Computational Molecular Biology(CMB)

<正>Computational Molecular Biology(ISSN 1927-5587)is an open access,peer reviewed journal published online by BioP ublisher.The Journal is publishing all the latest and outstanding research articles,letters,methods,and reviews in all areas of Computational Molecular Biology,covering new discoveries in molecular biology,from genes to genomes,using statistical,mathematical,and computational methods as well as new development of     

Computational Molecular Biology(CMB)

<正>Computational Molecular Biology(ISSN 1927-5587)is an open access,peer reviewed journal published online by BioP ublisher.The Journal is publishing all the latest and outstanding research articles,letters,methods,and reviews in all areas of Computational Molecular Biology,covering new discoveries in molecular biology,from genes to genomes,using statistical,mathematical,and computational methods as well as new development of     

Computational Molecular Biology(CMB)

正Computational Molecular Biology(ISSN 1927-5587)is an open access,peer reviewed journal published online by Bio Publisher.The Journal is publishing all the latest and outstanding research articles,letters,methods,and reviews in all areas of Computational Molecular Biology,covering new discoveries in molecular biology,from genes to     

Computational Molecular Biology(CMB)

正Computational Molecular Biology(ISSN 1927-5587)is an open access,peer reviewed journal published online by Bio Publisher.The Journal is publishing all the latest and outstanding research articles,letters,methods,and reviews in all areas of Computational Molecular Biology,covering new discoveries in molecular biology,from genes to genomes,using statistical,mathematical,and computational methods as well as new     

Computational Molecular Biology (CMB)

正Computational Molecular Biology(ISSN 1927-5587)is an open access,peer reviewed journal published online by Bio Publisher.The Journal is publishing all the latest and outstanding research articles,letters,methods,and reviews in all areas of Computational Molecular Biology,covering new discoveries in molecular biology,from genes to     

Computational Molecular Biology(CMB)

正Computational Molecular Biology(ISSN 1927-5587)is an open access,peer reviewed journal published online by Bio Publisher.The Journal is publishing all the latest and outstanding research articles,letters,methods,and reviews in all areas of Computational Molecular Biology,covering new discoveries in molecular biology,from genes to     

Computational Molecular Biology(CMB)

正Computational Molecular Biology(ISSN 1927-5587)is an open access,peer reviewed journal published online by Bio Publisher.The Journal is publishing all the latest and outstanding research articles,letters,methods,and reviews in all areas of Computational Molecular Biology,covering new discoveries in molecular biology,from genes to