CBL教学法在医学微生物学留学生教学中的构建与实践

目的在医学微生物学的留学生教学中探索与实践CBL教学法。方法通过案例设计,教师培训,课程设置及考核与评价,在我校留学生的医学微生物学教学中构建了CBL教学法。结果激发了学生的学习兴趣,拓宽了学生的知识面,学生分析问题解决问题的能力得到改善,同时也促进了教师的专业水平。结论 CBL教学法可以提高留学生医学微生物学教学效果。     

反例微视频教学法在“微生物学实验”课程中的实践研究

"微生物学实验"是生物类相关专业的一门必修课程,该课程的开展对提高学生实验技能和理解微生物学知识原理至关重要。因此,不断探索和改进实验课程教学方法、减少学生的错误实验操作、提高实验课堂教学效率是任课教师的基本任务。反例微视频教学法是将传统的案例教学法、反例教学法和当下流行的微课程相结合的一种教学方法。本文阐述了该教学法的原理、基本操作流程、课堂应用效果和存在的问题。该教学法的实施能较好地提高实验课堂效率,大幅减少学生错误实验操作的次数,值得在本科生物类实验课堂中进行推广。     

PBL 教学法在成教班生物化学教学中的应用体会

生物化学是一门"教师难教、学生难学"的医学基础课程,利用成人继续教育学生具备一定的临床经验的优势,将PBL教学法应用于成人继续教育乡医班生物化学教学中,激发了学生的学习兴趣和主动性,提高了学生分析问题和解决问题的能力,同时对教师综合素质提出了更高的要求。与传统教学法相比,PBL教学能够达到学生学与教师教的相互促进,提高了教学效果,符合新形势下教学改革的需求。     

基于微信平台的微课程教学法在“微生物学及检验技术”实验课教学中的应用与研究

为了激发医学检验技术专业学生对"微生物学及检验技术"实验课的学习兴趣、训练实验技能、拓展创新思维、促进素质教育,我们探索了基于微信平台的微课程教学法在该课程实验课的应用。实践证明微课程教学法能有效提升医学检验技术专业学生对该课程的喜爱程度,并有利于学生提升学科成绩,同时有效地增强了学生对学科前沿知识的关注度。     

PBL（Problem-based Learning）法在遗传学研究生专业课教学中的应用与探索

研究生教育的宗旨是培养具有创新能力的专业人才。为了突破传统教学模式的局限性,提高研究生教学质量,在遗传学研究生课程＂现代遗传学研究进展＂的教学中进行了PBL（Problem-based Learning）教学法的尝试与探索,采用学生自主学习和小组讨论为主,教师积极引导的方法。从根本上改变了传统的以教师为主的灌输式教学模式,极大地提高了学生的自主创新学习能力及学习的积极性,取得了良好的教学效果。     

以问题为中心的教学法在生理教学中的应用探讨

本文针对以问题为中心的教学法在教学工作中的应用体会与作用进行了探讨。并通过问卷调查的方法对教学效果与学生对该教学法的认可程度进行了验证。结果表明,该教学法可激发学生学习的兴趣,让学生有针对性地去探索并运用理论知识,以提高分析和解决问题的能力,以促进学生对知识的掌握和运用,达到最终的教学目标。     

基于“对分课堂”教学模式下普通生物学教学探索

当前普通生物学教学质量有待提高,一大批一线教师尝试不同的教学方法来提高教学质量,但仍然有很多问题需要进一步解决。笔者在比较多种教学方法后,尝试了一种新型教学模式"对分课堂"。该教学模式的实施结果发现,"对分课堂"有助于培养大学生良好的自学能力、独立思考能力和讨论学习能力,增强学生的学习主动性、积极性和便捷性,增加学生间、师生间的互动交流;提高大学生相互尊重和理解的素养;缓解教学课时不足与教学大纲内容较多之间的矛盾。总之,"对分课堂"对提高普通生物学教学质量起到重要的作用。     

以问题为中心的教学法在生理教学中的应用探讨

本文针对以问题为中心的教学法在教学工作中的应用体会与作用进行了探讨.并通过问卷调查的方法对教学效果与学生对该教学法的认可程度进行了验证.结果表明,该教学法可激发学生学习的兴趣,让学生有针对性地去探索并运用理论知识,以提高分析和解决问题的能力,以促进学生对知识的掌握和运用,达到最终的教学目标.     

“三明治”教学在皮肤性病学教学中的实践

目的探讨"三明治"教学法对学生主动学习能力和教学效果的影响。方法对2016级五年制临床医学专业生在皮肤性病学教学中,采用"三明治"教学法结合传统教学法的教学模式。结果 "三明治"教学法能有效调动学生的学习积极性和主动性,提高学生自主学习能力,传统教学法系统地传授了专业理论知识。结论在皮肤性病学教学中采用"三明治"教学法结合传统教学模式,可取得优于传统教学法的教学效果。     

案例教学法在医学院校生物化学教学中的应用

生物化学是高等医学院校难学、难教的课程.采用案例教学法应用于生物化学理论课的教学,这种方法提高了学生的学习兴趣和学习主动性,培养了学生的临床思维能力和分析问题、解决问题的能力;另一方面也提高了教师自身的知识水平和综合素质.案例教学使生物化学课程的教学效果显著提高,是一种值得推广的教学方法.     

Recent advances in the study of Kaposi's sarcoma-associated herpesvirus replication and pathogenesis

It has now been over twenty years since a novel herpesviral genome was identified in Kaposi's sarcoma biopsies. Since then, the cumulative research effort by molecular biologists, virologists, clinicians, and epidemiologists alike has led to the extensive characterization of this tumor virus, Kaposi's sarcoma-associated herpesvirus(KSHV; also known as human herpesvirus 8(HHV-8)), and its associated diseases. Here we review the current knowledge of KSHV biology and pathogenesis, with a particular emphasis on new and exciting advances in the field of epigenetics. We also discuss the development and practicality of various cell culture and animal model systems to study KSHV replication and pathogenesis.     

The structure, reproduction and taxonomy of Vidalia and Osmundaria (Rhodophyta, Rhodomelaceae)

Comprises species occurring mostly in subtidal habitats in tropical, subtropical and warm-temperate areas of the world. An analysis of the type species, V. spiralis (Sonder) Lamouroux ex J. Agardh, a species from Australia, establishes basic characters for distinguishing species in the genus. These characters are (1) branching patterns of thalli, (2) flat blades that may be spiralled on their axis, (3) width of the blade, (4) primary or secondary derivation of sterile and fertile branchlets and (5) position of sterile and fertile branchlets on the thalli. Application of the latter two characters provides an important basic method for separation of species into three major groups. Osmundaria , a genus known only in southern Australia, was studied in relation to Vidalia , and its separation from the Vidalia assemblage is not accepted. Species of Vidalia therefore are transferred to the older genus name, Osmundaria. Two new species, Osmundaria papenfussii and Osmundaria oliveae are described from Natal. Confusion in the usage of the epithet, Vidalia fimbriala Brown ex Turner has been clarified, and Vidalia gregaria Falkenberg, described as an epiphyte on Osmundaria pro/ifera Lamouroux, is revealed to be young branches of the host, Osmundaria prolifera.     

New or rare chromosome counts in Artemisia L. (Asteraceae, Anthemideae) and related genera from Kazakhstan

Fifteen chromosome counts of six Artemisia taxa and one species of each of the genera Brachanthemum, Hippolytia, Kaschgaria, Lepidolopsis and Turaniphytum are reported from Kazakhstan. Three of them are new reports, two are not consistent with previous counts and the remainder are confirmations of very scarce (one to four) earlier records. All the populations studied have the same basic chromosome number, x = 9, with ploidy levels ranging from 2x to 6x. Some correlations between ploidy level, morphological characters and distribution are noted.     

肝癌中HBV和HCV基因和抗原的分布及意义

采用原位分子杂交方法检测HCV RNA及HBV X基因;采用免疫组织化学方法研究HCV核心抗原,非结构区C33c抗原及HBxAg在肝细胞肝癌中的定位及分布.结果表明(1)HCV RNA、HBV X基因在肝细胞肝癌组织检出率分别为40%(55/136)和82%(112/136).HCV RNA定位于癌细胞的胞浆内,阳性细胞呈散在、灶状及弥漫分布三种形式;HBV X基因在肝癌细胞中的分布呈胞浆型、核型及核浆型,阳性细胞也呈上述三种分布形式;(2)HCV C33c抗原、核心抗原在肝细胞肝癌中的阳性率为81%(133/164)及86%(141/164).C33c抗原定位于癌细胞及肝细胞的胞浆内;核心抗原既定位于癌细胞核中,又可定位于胞浆中.C33c抗原阳性细胞以灶状分布为主;而核心抗原阳性细     

Selection with two alleles and complete dominance

For a plant selection model with frequency-independent viabilities, fertilities and selfing rates, it is shown that apart from global fixation, for certain parameter combinations a protected polymorphism and facultative fixation (either allele may become fixed according to initial frequencies) may both occur. Facultative fixation requires different selling rates for the dominant and recessive type. Protection of the polymorphism requires resource allocation for male and female function. In this connection the problem of purely genetically caused population extinction is discussed.
For general frequency dependence and regular segregation, the chances for establishment of a completely recessive gene are compared to those of a completely dominant gene. It is proven that the process of establishment of the recessive gene, despite a fitness advantage, may be considerably endangered by drift effects if random mating prevails. The recessive gene may reach the same effectivity in establishment as a dominant gene, only if the recessive homozygote mates exclusively with its own type during the period of establishment.