共查询到20条相似文献,搜索用时 15 毫秒
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Background
Identification and characterization of novel Plasmodium gene families is necessary for developing new anti-malarial therapeutics. The products of the Plasmodium falciparum gene, MB2, were shown previously to have a stage-specific pattern of subcellular localization and proteolytic processing. 相似文献13.
Laura I Klepp Marcelo Soria Federico C Blanco María V Bianco María P Santangelo Angel A Cataldi Fabiana Bigi 《BMC molecular biology》2009,10(1):3
Background
The exported repetitive protein (erp) gene encodes a secreted 36-kDa protein with a central domain containing several proline-glycine-leucine-threonine-serine (PGLTS) repeats. It has been demonstrated that erp is a virulence-associated factor since the disruption of this gene impairs the growth of Mycobacterium bovis and Mycobacterium tuberculosis in mice. 相似文献14.
Radim Cegan Gabriel AB Marais Hana Kubekova Nicolas Blavet Alex Widmer Boris Vyskot Jaroslav Doležel Jan Šafář Roman Hobza 《BMC plant biology》2010,10(1):180
Background
The evolution of sex chromosomes is often accompanied by gene or chromosome rearrangements. Recently, the gene AP3 was characterized in the dioecious plant species Silene latifolia. It was suggested that this gene had been transferred from an autosome to the Y chromosome. 相似文献15.
Eishi?Funakoshi Takamitsu?Hori Tokuko?Haraguchi Yasushi?Hiraoka Jun?Kudoh Nobuyoshi?Shimizu Fumiaki?Ito
Background
Previously we cloned the human MNB/DYRK1A gene from the "Down syndrome critical region" on chromosome 21. This gene encodes a dual specificity protein kinase that catalyzes its autophosphorylation on serine/threonine and tyrosine residues. But, the functions of the MNB/DYRK1A gene in cellular processes are unknown. 相似文献16.
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Mónica Oleastro Rita Cordeiro Armelle Ménard Yoshio Yamaoka Dulciene Queiroz Francis Mégraud Lurdes Monteiro 《BMC microbiology》2009,9(1):248
Background
The homB gene is a Helicobacter pylori disease-marker candidate, strongly associated with peptic ulcer disease, while homA, its paralogue gene with 90% sequence identity, is correlated with non-ulcer dyspepsia. The HomB encoded outer membrane protein was shown to contribute to the proinflammatory properties of H. pylori and also to be involved in bacterial adherence. 相似文献18.
Tao Dong Sarah M Chiang Charlie Joyce Rosemary Yu Herb E Schellhorn 《BMC microbiology》2009,9(1):118-13
Background
Though RpoS is important for survival of pathogenic Escherichia coli in natural environments, polymorphism in the rpoS gene is common. However, the causes of this polymorphism and consequential physiological effects on gene expression in pathogenic strains are not fully understood. 相似文献19.
Yanping Han Jingfu Qiu Zhaobiao Guo He Gao Yajun Song Dongsheng Zhou Ruifu Yang 《BMC microbiology》2007,7(1):96
Background
Environmental modulation of gene expression in Yersinia pestis is critical for its life style and pathogenesis. Using cDNA microarray technology, we have analyzed the global gene expression of this deadly pathogen when grown under different stress conditions in vitro. 相似文献20.
Vannini V Rodríguez A Vera JL de Valdéz GF Taranto MP Sesma F 《Biotechnology letters》2011,33(8):1625-1632