Deep tissue infection by an invasive human fungal pathogen requires lipid-based suppression of the IL-17 response

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Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity

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Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins

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Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

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Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal

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The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development

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Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions

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Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome

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Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria

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Microbiota regulate innate immune signaling and protective immunity against cancer

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Antigen presentation between T cells drives Th17 polarization under conditions of limiting antigen

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A Bartonella Effector Acts as Signaling Hub for Intrinsic STAT3 Activation to Trigger Anti-inflammatory Responses

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Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity

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Human gut bacterial metabolism drives Th17 activation and colitis

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The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming

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METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate γδ T1 and γδ T17 cells

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IL-22 promotes the formation of a MUC17 glycocalyx barrier in the postnatal small intestine during weaning

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Transmembrane Coordination of Preprotein Recognition and Motor Coupling by the Mitochondrial Presequence Receptor Tim50

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Mitochondrial Oxidative Phosphorylation Regulates the Fate Decision between Pathogenic Th17 and Regulatory T Cells

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Metabolic modeling of single Th17 cells reveals regulators of autoimmunity

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