Temporal dissection of an enhancer cluster reveals distinct temporal and functional contributions of individual elements

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Multimodal regulatory elements within a hormone-specific super enhancer control a heterogeneous transcriptional response

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PAX3-FOXO1 coordinates enhancer architecture,eRNA transcription,and RNA polymerase pause release at select gene targets

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Interplay between CTCF boundaries and a super enhancer controls cohesin extrusion trajectories and gene expression

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Divergent expression of paralogous genes by modification of shared enhancer activity through a promoter-proximal silencer

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An oncogenic enhancer encodes selective selenium dependency in AML

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Synthetic regulatory genomics uncovers enhancer context dependence at the Sox2 locus

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Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex

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A single-nucleotide mutation within the TBX3 enhancer increased body size in Chinese horses

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Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function

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Deletion mapping of regulatory elements for GATA3 in T cells reveals a distal enhancer involved in allergic diseases

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SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling

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SPT5 stabilizes RNA polymerase II,orchestrates transcription cycles,and maintains the enhancer landscape

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Regulators of male and female sexual development are critical for the transmission of a malaria parasite

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A Highly Conserved Circular RNA Is Required to Keep Neural Cells in a Progenitor State in the Mammalian Brain

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DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism

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In the mouse cortex,oligodendrocytes regain a plastic capacity,transforming into astrocytes after acute injury

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The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages

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Single-cell chromatin accessibility identifies enhancer networks driving gene expression during spinal cord development in mouse

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High-throughput functional dissection of noncoding SNPs with biased allelic enhancer activity for insulin resistance-relevant phenotypes

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