Cell-Cycle Asynchrony Generates DNA Damage at Mitotic Entry in Polyploid Cells

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Mapping the Human Kinome in Response to DNA Damage

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Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage

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Phosphorylation of p53 by TAF1 Inactivates p53-Dependent Transcription in the DNA Damage Response

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A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response

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PRP19 Transforms into a Sensor of RPA-ssDNA after DNA Damage and Drives ATR Activation via a Ubiquitin-Mediated Circuitry

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Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response

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Dissection of DNA Damage Responses Using Multiconditional Genetic Interaction Maps

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Highlights? A resource of genetic modules and networks induced by distinct types of DNA damage ? Networks distinguish DNA damage response pathways with high statistical power ? Rtt109, a histone acetyltransferase, affects the mutagenic bypass of DNA lesions ? The neddylation machinery and Irc21 affect cell-cycle control and genome stability     

Thrombopoietin-Increased DNA-PK-Dependent DNA Repair Limits Hematopoietic Stem and Progenitor Cell Mutagenesis in Response to DNA Damage

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Highlights? Mpl loss increases γ-irradiation-induced genomic instability in HSPCs ? TPO promotes DNA repair in vitro and in vivo in HSPCs ? TPO increases DNA-PK activity and NHEJ-mediated repair efficiency in HSPCs ? A single TPO injection before mouse TBI limits long-term HSC injury and mutagenesis     

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18

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Highlights

• •Protein interaction screen of SETD1A/COMPASS complex subunits.
• •Unexpected interaction with DNA damage protein RAD18 was confirmed for SETD1A, but not for other subunits.
• •SETD1A and/or RAD18 influence each other's mRNA and protein expression levels, and disruption of either gene elicits a similar DNA damage sensitivity phenotype.

     

Recent progress on DNA based walkers

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Rethinking transcription coupled DNA repair

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DNA polymerases and biotechnological applications

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Fine-Tuning of DNA Damage-Dependent Ubiquitination by OTUB2 Supports the DNA Repair Pathway Choice

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Catalysts for RNA and DNA modification

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DNA nanotechnology and fluorescence applications

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Nanomaterials and nanoclusters based on DNA modulation

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Interlocked DNA topologies for nanotechnology

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DNA barcoding of medicinal plant material for identification

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Metal-mediated DNA assembly with ligand-based nucleosides

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