南海北部珠江口盆地深水区LW5井晚渐新世——早中新世孢粉组合

本文对南海北部珠江口盆地深水区LW5井3 070—3 480m井段81个孢粉样品进行了分析,共鉴定86个孢粉属种类型;另有沟鞭藻和有孔虫内膜。根据孢粉和藻类化石组合面貌、丰度变化和特征分子的分布规律,将研究井段地层划分为2个孢粉组合:3 070—3 325m井段为Polypodiaceaesporites-Dinocysts组合,层位相当于珠江组,时代为早中新世。本组合含丰富的沟鞭藻和微有孔虫,孢粉以Graminidites,Zonocostatites和Chenopodipollis等为主,沉积环境为滨浅海,气温较高,指示了湿润的热带、亚热带古气候;3 330—3 470m井段为AlnipollenitesPinuspollenites组合,与珠海组层位相当,地层时代为晚渐新世。本组合沟鞭藻和微有孔虫少量出现,孢粉含丰富的Pinuspollenites和Abietineaepollenites,出现较多的Cedripites等,反映海陆交互的古环境,显示了气温低的亚热带古气候。     

南海北部琼东南盆地崖北凹陷渐新世沟鞭藻类

本文选取南海北部琼东南盆地崖北凹陷Y-2-X井2 197.6～4 288.5 m井段60个样品进行了沟鞭藻化石分析,结果每个样品均发现了沟鞭藻化石,共鉴定34属60种.根据沟鞭藻分布特征,对研究井段的地层进行了划分.2 197.6～2 548.1 m井段,沟鞭藻化石稀少,未建立组合.2 709.7～4 288.5 m建...     

新疆准噶尔盆地芳3井晚白垩世孢粉组合的发现及其地质意义

准噶尔盆地腹部芳3井紫泥泉子组所夹灰色泥岩中产丰富的盘星藻、葡萄藻等藻类、疑源类化石及一定数量的孢粉化石。孢粉化石计75属160种,并首次在新疆地区发现了可靠的鹰粉型化石Aquilapollenites以及在我国主要产于松辽盆地和广东三水盆地上白垩统的“大孢子”化石Balmeisporites,建立Schizaeoisporites grandus-Parcisporites parvisaccus-Liliacidites creticus(GPC)组合。通过对部分孢粉属种已知地质分布的分析以及与国内外部分地区晚白垩世孢粉组合的对比,将GPC组合的时代确定为晚白垩世坎潘期至马斯特里赫特期。根据紫泥泉子组的沉积特点及孢粉组合特征,认为晚白垩世准噶尔盆地应归属西北-东南孢粉植物区,局部层段沉积时期气候比较湿润,孢粉组合具有我国东北孢粉植物区与西北-东南孢粉植物区的过渡特点。     

新疆三塘湖盆地塘浅3井中侏罗世孢粉组合

本文对在新疆三塘湖盆地塘浅3井106-701m层段发现的孢粉化石进行了系统的分析研究,共获孢子花粉52属120种（包括相似种和未定种）,疑源类化石2属2种及一个未定类型,根据孢粉属种及其含量的变化,自下而上分为两套组合;1）Cyathidites minor-Osmundacidites-Cycadopites-Quadraeculina组合;2）Kraeuselisporites ma-nasiensis-Classopollis-Quadraeculina组合,第一组合产于该井413-710m层段。时代归为中侏罗世早期,赋存地层相当于西山窑组;第二组合产于106-413m,时代归为中侏罗世晚期,赋存地层相当于头屯河组,系统分析组合中主要孢粉属种及其母体植物的生长环境,推测新疆三塘湖盆地及其周围地区在中侏罗世早期为温带或亚热带气候,晚期为亚热带气候。     

青海柴达木盆地鄂博梁2号井早侏罗世孢粉植物群及其地层意义

本文系统研究了产自青海柴达木盆地鄂博梁2号井4501-4852．7m层段中的孢粉化石,共计55属96种,其中蕨类植物孢子25属45种,裸子植物花粉28属49种,疑源类2属2种。组成以Cyathidites-Deltoidospora-Piceites-Quadraeculina-Classopollis为特征的孢粉组合。根据组合内一些重要分子的地质时限讨论及与有关孢粉组合的对比,其时代应归为早侏罗世晚期。     

赤道几内亚里奥姆尼盆地K-1井白垩纪生物地层

赤道几内亚境内西部里奥姆尼(Rio Muni)盆地K-1井白垩纪地层含丰富的沟鞭藻类,孢粉,钙质超微和介形类等化石,自下而上可以划分出3个生物组合带,A带含孢粉Classopollis-Cicatricosisporites-Inaperturopollenites-Afropollis组合和介形类Hourcqia,Petrobrasia等,时代属于Aptian—Albian期。B带含孢粉Schizaeoisporites-Ephedripites-Jugella-Tricolpites组合,沟鞭藻类Dinogymnium,Oligosphaeridium,Impletosphaeridium,Florentinia,以及钙质超微化石Eiffelithus eximius,Lithastrinus grillii,Eprolithus moratus等,时代为Cenomanian—Santonian期。C带含孢粉Polypodiaceae-Psophosphaera-Proteacidites-Tricolpopollenites组合,沟鞭藻类Peridiniaceae,Dinogymnium,Tenua,Spiniferites,和钙质超微化石Micula concave,Arkangelskiella cymbiformis等,时代为Campanian—Maastrichtian期。     

新疆三塘湖盆地塘浅3井早侏罗世孢粉组合

本文对在新疆三塘湖盆地塘浅3井701－834m层段发现的孢粉植物群进行了系统的分析研究,共获孢粉45属93种（包括1新种）,疑源类化石5属5种及一个未定类型,组成以Osmundacidites-Piceites-Pinuspollenites-Quadraeculina为主的孢粉组合,根据孢粉组合特征,认为其时代应归为早株罗世晚期,对组合中主要孢粉属种可能的母体植物的生长环境进行分析,推测新疆三塘湖地区在早侏罗世晚期为温带－亚热带气候。     

依兰-伊通地堑北部早白垩世孢粉组合新发现

近年来,在汤原断陷钻井地层中发现了较丰富的早白垩世孢粉化石,本文依据汤原断陷汤D7井458.0-1100.0m井段新发现的孢粉化石,建立了3个孢粉化石组合,即：Cyathidites-Pilosisporites-Cardioangulina组合,Taxodiaceaepollenites-Pinuspollenites-Cyathidites组合和Cyathidites-Cicatricosisporites-Triporoletes-Pilosisporites组合。孢粉组合完全可以与松辽盆地登娄库组对比,其时代为早白垩世阿普第一阿尔必期。     

沟鞭藻的起源:分子地球化学证据

沟鞭藻为单细胞的原始的海洋生物。古生物学家根据形态特征,超微结构和生物化学信息认为沟鞭藻可能在前寒武纪时已存在,并推测古生代疑源类可能是现代沟鞭藻的先祖,但确凿的沟鞭藻囊孢的化石记录始于晚三叠世。生物标志物以分子化石的形式记录了沟鞭藻的起源及演化历史。在古生代及前寒武纪地层中甲藻甾烷及三芳沟鞭藻的检出,建立了沟鞭藻与其古代先祖（疑源类）的联系,提供了沟鞭藻先祖前寒武纪存在的证据。     

新疆准噶尔盆地东部覆盖区锅底坑组的发现及其化石证据

本文对准噶尔盆地东部CS-1井1 082—1 126m井段10块样品中所含孢粉和大孢子化石进行了比较系统的分析研究,共获得孢粉化石68属114种,以及少量大孢子化石,并建立Limatulasporites fossulatus-Klausipollenites schaubergeri孢粉组合,组合以Limatulasporites fossulatus和Kraeuselisporites spinullous比较发育,并见有Klausipollenites schaubergeri,Lundbladispora和Welwitschipollenites clarus等为主要特征。根据孢粉组合特征和大孢子化石的分布规律,详细讨论了含化石井段地层的时代及层位,认为该段地层的时代为晚二叠世晚期至早三叠世早期,层位为锅底坑组。     

Crystal structure, detonation performance, and thermal stability of a new polynitro cage compound: 2, 4, 6, 8, 10, 12, 13, 14, 15-nonanitro-2, 4, 6, 8, 10, 12, 13, 14, 15-nonaazaheptacyclo [5.5.1.13, 11. 15, 9] pentadecane

A new polynitro cage compound 2, 4, 6, 8, 10, 12, 13, 14, 15-nonanitro-2, 4, 6, 8, 10, 12, 13, 14, 15-nonaazaheptcyclo [5.5.1.1(3,11).1(5,9)] pentadecane (NNNAHP) was designed in the present work. Its molecular structure was optimized at the B3LYP/6-31 G(d,p) level of density functional theory (DFT) and crystal structure was predicted using the Compass and Dreiding force fields and refined by DFT GGA-RPBE method. The obtained crystal structure of NNNAHP belongs to the P-1 space group and the lattice parameters are a = 9.99 ?, b = 10.78 ?, c = 9.99 ?, α = 90.01°, β = 120.01°, γ = 90.00°, and Z = 2, respectively. Based on the optimized crystal structure, the band gap, density of state, thermodynamic properties, infrared spectrum, strain energy, detonation characteristics, and thermal stability were predicted. Calculation results show that NNNAHP has detonation properties close to those of CL-20 and is a high energy density compound with moderate stability.     

Distribution of N,P, K,Ca, Mg,S, Zn,Fe, Mn and Cu in groundnut

Summary Concentration of N, P, K, Ca, Mg and S in summer groundnut crop was higher than in kharif while Zn, Fe, Mn and Cu contents were higher in summer crop. Kernel's N, P and Zn; Leaflet's Ca and Mn; Stem's K and Fe; Root's S and Cu and Petiole's Mg contents were highest. Shell's N, P, K, Mg, S, Zn and Cu; Kernel's Ca, Fe and Mn contents were the least. N, P, K, S, Zn and Cu concentrations decreased linearly as the crop grew. Ca, Mg, Fe and Mn concentrations did not display any distinct pattern. Ca concentration was positively correlated with pod yield in both the seasons.     

Relations of the Al,B, Ba,Br, Ca,Cl, Cu,Fe, K,Li, Mg,Mn, Na,P, S,Si, Sr,and Zn mass fractions to morphometric parameters in pediatric and nonhyperplastic young adult prostate glands

The variation with age of the 18 trace element mass fractions and some histological characteristics of intact prostate glands of 50 subjects aged 0–30 years was investigated by instrumental neutron activation analysis, inductively coupled plasma atomic emission spectrometry, and a quantitative morphometric analysis. Mean values ± standard error of the mean (M ± SΕΜ) for the mass fractions (in milligrams per kilogram wet tissue) of these trace elements in pre-puberty were: Al 28.5 ± 9.0, B 0.40 ± 0.11, Ba 1.48 ± 0.44, Br 10.5 ± 1.5, Ca 241 ± 30, Cl 3,203 ± 278, Cu 3.51 ± 0.89, Fe 33.7 ± 4.1, K 2,364 ± 145, Li 0.020 ± 0.004, Mg 153 ± 23, Mn 0.46 ± 0.06, Na 2,286 ± 130, P 1,391 ± 100, S 1,698 ± 132, Si 62 ± 11, Sr 0.38 ± 0.08, and Zn 27.6 ± 2.3. During puberty and postpuberty, when there is a significant increase in circulating androgens, the mean values were: Al 7.2 ± 1.4, B 0.21 ± 0.05, Ba 0.25 ± 0.06, Br 5.8 ± 1.0, Ca 433 ± 81, Cl 2,314 ± 201, Cu 1.77 ± 0.13, Fe 20.9 ± 1.6, K 2,585 ± 118, Li 0.0088 ± 0.0014, Mg 232 ± 27, Mn 0.34 ± 0.04, Na 1,875 ± 107, P 1,403 ± 98, S 1,673 ± 73, Si 22.2 ± 3.1, Sr 0.22 ± 0.03, and Zn 93.3 ± 8.9. Mean values (M ± SΕΜ) of percent volumes (%) of the stroma, epithelium and lumen in the prostate before puberty were 73.4 ± 2.6, 20.4 ± 1.7, and 4.45 ± 0.94, respectively, versus 46.5 ± 2.5, 38.5 ± 1.9, and 14.9 ± 1.2 during puberty and postpuberty. This work’s results confirm that the Zn mass fraction in prostate tissue is an androgen-dependent parameter. For the first time it has been demonstrated that the glandular lumen is a main pool of Ca, Mg, and Zn accumulation and that the stroma is a main pool of Al, B, Ba, Br, Cl, Cu, Fe, Mn, Na, and Si accumulation in the normal human prostate, for the age range 0–30 years. It was concluded that the Ca, Mg, and Zn binds tightly within the prostatic fluid, because the volume of glandular lumen reflects the volume of prostatic fluid.     

Simultaneous measurement of the trace elements Al, As, B, Be, Cd, Co, Cu, Fe, Li, Mn, Mo, Ni, Rb, Se, Sr, and Zn in human serum and their reference ranges by ICP-MS

The goal of this article was to establish reference ranges of the concentration of trace elements in human serum and to compare these results with those reported by other authors. We describe the sample preparation and measurement conditions that allow the rapid, precise, and accurate determination of Al, As, B, Be, Cd, Co, Cu, Fe, Li, Mn, Mo, Ni, Rb, Se, Sr, and Zn in human serum samples (n=110) by inductively coupled plasma-mass spectrometry (ICP-MS). Accuracy and precision were determined by analyzing three reconstituted reference serum samples by comparison with other methods and by the standard addition procedure. The advantages of the ICP-MS method include short time of analysis of the elements mentioned, low detection limit, high precision, and high accuracy. Disadventages include a high risk of contamination due to the presence of some of the elements of interest in the environment, the relatively delicate sample handling, and the high cost of the equipment.     

Reference values for the concentrations of As,Cd, Co,Cr, Cu,Fe, I,Hg, Mn,Mo, Ni,Pb, Se,and Zn in selected human tissues and body fluids

This report attempts to formulate reference ranges of elemental concentrations for 15 trace elements in selected human tissues and body fluids. A set of samples consisting of whole blood, blood serum, urine, milk, liver, and hair were chosen and considered for 15 elements of biological significance: As, Cd, Co, Cr, Cu, F, Fe, I, Hg, Mn, Mo, Ni, Pb, Se, and Zn. The results represent wholly or partially data received from 40 countries of the global regions of Africa, Asia, Europe, North, South, and Central America, Australia, and New Zealand. This survey, even if qualitative, has been useful in demonstrating certain trends of trace-element scenarios around the world. It is of course recognized that both diet and environment exert a strong influence on the distribution pattern of several elements, such as As, Cd, Mn, Pb, Se, and Zn. A limited comparison of the available information on soil status of different countries reflected some interesting associations for elements, such as Mn and Zn. Importantly, this study revealed that only a few countries were in a position to identify a reasonable amount of data on samples requested for this project. Regretably, for a number of countries, any dependable data for even such essential elements as Cu, Fe, and Zn were not available. In view of the nutritional importance of many elements, the time is ripe for concerted efforts by intergovernmental agencies to initiate investigations or commission task forces/projects to generate reliable reference data for selected global regions, which sadly lack data of any kind at present.     

The Effect of Age and Gender on Al, B, Ba, Ca, Cu, Fe, K, Li, Mg, Mn, Na, P, S, Sr, V, and Zn Contents in Rib Bone of Healthy Humans

The effect of age and gender on major, minor, and trace element contents in the intact rib bone of 80 relatively healthy 15–55-year-old women and men was investigated. Contents or upper limit of contents of 16 chemical elements in the rib bone were determined by inductively coupled plasma atomic emission spectrometry (ICP-AES). Mean values (M?±?SΕΜ) for the mass fraction of Ba, Ca, Cu, Fe, K, Li, Mg, Na, P, S, Sr, and Zn (milligram per kilogram of dry bone) were as follows: 2.54?±?0.16, 171,400?±?4,050, 1.35?±?0.22, 140?±?11, 1,874?±?71, 0.049?±?0.011, 2,139?±?38, 5,378?±?88, 75,140?±?1,660, 1,881?±?51, 291?±?20, and 92.8?±?1.5, respectively. The upper limits of contents of Al, B, Mn, and V were <7.20, <0.65, <0.36, and <0.03, respectively. Statistically significant tendency for the Ca, Mg, and P content to decrease with age was found in the human rib bone, regardless of gender. The mass fraction of Fe in the male rib bone increases with age. It was shown that higher Ca, Mg, Na, P, and Sr mass fractions as well as lower Fe content were typical of female ribs as compared to those in male ribs.     

Potential Compounds for Oral Cancer Treatment: Resveratrol,Nimbolide, Lovastatin,Bortezomib, Vorinostat,Berberine, Pterostilbene,Deguelin, Andrographolide,and Colchicine

Oral cancer is one of the main causes of cancer-related deaths in South-Asian countries. There are very limited treatment options available for oral cancer. Research endeavors focused on discovery and development of novel therapies for oral cancer, is necessary to control the ever rising oral cancer related mortalities. We mined the large pool of compounds from the publicly available compound databases, to identify potential therapeutic compounds for oral cancer. Over 84 million compounds were screened for the possible anti-cancer activity by custom build SVM classifier. The molecular targets of the predicted anti-cancer compounds were mined from reliable sources like experimental bioassays studies associated with the compound, and from protein-compound interaction databases. Therapeutic compounds from DrugBank, and a list of natural anti-cancer compounds derived from literature mining of published studies, were used for building partial least squares regression model. The regression model thus built, was used for the estimation of oral cancer specific weights based on the molecular targets. These weights were used to compute scores for screening the predicted anti-cancer compounds for their potential to treat oral cancer. The list of potential compounds was annotated with corresponding physicochemical properties, cancer specific bioactivity evidences, and literature evidences. In all, 288 compounds with the potential to treat oral cancer were identified in the current study. The majority of the compounds in this list are natural products, which are well-tolerated and have minimal side-effects compared to the synthetic counterparts. Some of the potential therapeutic compounds identified in the current study are resveratrol, nimbolide, lovastatin, bortezomib, vorinostat, berberine, pterostilbene, deguelin, andrographolide, and colchicine.