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M Korcok 《CMAJ》1998,159(9):1165-1166
Unlike Canada''s voluntary blood-collection system, the US system routinely makes use of donations from paid donors. Milan Korcok reports that this is starting to cause some concern, since infection levels tend to be higher among those who are paid for their blood.  相似文献   

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Commentary on human cloning   总被引:1,自引:0,他引:1  
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On cloning human beings   总被引:2,自引:0,他引:2  
de Melo-Martin I 《Bioethics》2002,16(3):246-265
The purpose of this paper is to show that arguments for and against cloning fail to make their case because of one or both of the following reasons: 1) they take for granted customary beliefs and assumptions that are far from being unquestionable; 2) they tend to ignore the context in which human cloning is developed. I will analyze some of the assumptions underlying the main arguments that have been offered for and against cloning. Once these assumptions are critically analyzed, arguments both rejecting and supporting human cloning seem to lose weight. I will first briefly present the main arguments that have been proposed against cloning and I will argue that they fail to establish their case. In the next section I will evaluate some of the positive arguments that have been offered supporting such technology. This analysis will show that the case for cloning also fails. Finally, I will maintain that because critics and especially supporters of this technology neglect the context in which human cloning is developed and might be implemented, their arguments are far from compelling.  相似文献   

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From a human genomic library we have isolated and sequenced a beta-actin-related pseudogene (Hbeta Ac-psi l) which is free of intervening sequences. Several nucleotide insertions and deletions and translational stop codons generated within the protein-coding region indicate that this gene is functionless.  相似文献   

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Mary P. Manno 《CMAJ》2010,182(10):1081
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A human T lymphoblastic cell line lacks lamins A and C   总被引:8,自引:3,他引:5       下载免费PDF全文
Lamins A, B and C, the three major proteins of nuclear envelope, constitute a class of intermediate filament polypeptides. We have compared the amount of these polypeptides in two human cell lines, epithelial HeLa cells and T lymphoblasts KE 37. It was found that the three lamins were present in roughly equimolar stoichiometry in HeLa cells, while lamin B was the unique lamin component in T lymphoblasts. Moreover, 3-kb mRNA of lamin A and 2.1-kb mRNA of lamin C were detected with a human cDNA probe in HeLa cells but not in T lymphoblasts. These results suggest that (i) lamin B can build up the lamina structure in actively dividing somatic cells by itself, and (ii) lamin expression in lymphoid cells may be subject to important quantitative variations. Comparison of the lamin composition of human cloned T lymphocytes and Epstein-Barr virus-transformed human B lymphocytes confirmed this statement. The lamin B level was nearly equivalent in both cells but the content of lamins A and C varied to a large extent, being low in T cells and high in B cells.  相似文献   

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Williams N 《Current biology : CB》2004,14(22):R937-R938
The United Nations postponed again a controversial vote on the issue of therapeutic cloning of human stem cells, hampering the widely supported opposition to reproductive cloning but many countries are developing their own legislation.  相似文献   

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