SYNTHESIS AND BIOLOGICAL ACTIVITIES OF (Z) AND (E) α-ETHENYL ACYCLONUCLEOSIDES

Synthesis of Z and E ethenyl acyclonucleosides (6a-e and 7a-e) via Michael addition of nucleobases with the diethyl acetylenedicarboxylate is described. The structures of compounds have been confirmed by spectral data. New compounds were found to be inactive against DNA and RNA viruses.     

STATUS OF LUCIOCYPRINUS AND FUSTIS(OSTEICHTHYE:CYPRINIDAE)

Fustis Lin, 1932 is a synonym of Luciocyprinus Vaillant, 1904,F. virus Lin,1932 and Barbus normani Tchang,1935 are synonyms of L.langsoni Vaillant, 1904. The holotype of L. langsoni is illustrated for the first time. Although the first fish species from the Indochinese area (sensu Kottelat, in press) was described some 150 years ago, this area is still badly known from the ichthyological point of view. This is more particularly the case of the fish fauna of the northern part of Viet Nam for which we only have a few scarce data, this being essentially due to both difficulties of access and independance wars. Most of the work done on fishes of that area has been done by French scientists (e. g. Bocourt, Sauvage, Vaillant, Pellegrin, Chevey). The Works of some of them have often been overlooked or are hardly usable due to very poor standards. In 1904, Vaillant described a large cyprinid from the Song-Ki-Kong River at Lang-Son(Viet Nam) near the Chinese border. The Song-Ki-Kong Riverat Lang-Son(Viet Nam)nea     

SYNTHESIS AND BIOLOGICAL EVALUATION OF CONFORMATIONALLY RESTRICTED AND NUCLEOBASE-MODIFIED ANALOGS OF THE ANTICANCER COMPOUND 3′-C-ETHYNYLCYTIDINE (ECYD)

A series of conformationally restricted and nucleobase-modified analogs of the anticancer compound 3′-C-ethynylcytidine (ECyd) and its uracil analog (EUrd) have been synthesized. While none of, the conformationally restricted analogs displayed anticancer activity, 5-iodo-EUrd and 5-bromo-EUrd displayed potent anticancer activity with IC50 values of 35 nM and 0.73 μM.     

POLLEN MORPHOLOGY OF HAPLOPAPPUS AND RELATED GENERA (COMPOSITAE—ASTEREAE)

Pollen grains of Haplopappus and related genera in the subtribe Solidaginae from North and South America were examined by light and scanning electron microscopy. The grains are consistently tricolporate and echinate. Some genera can be distinguished by pollen size, spine length, and number of spine rows between colpi. Based on these characters, the divergence of Benitoa from other members of the subtribe, as indicated by its morphology and secondary chemistry, is supported. Additionally, the recently suggested absence of a close relationship between Pyrrocoma and Oonopsis is indicated by their contrasting pollen types. This study demonstrates the potential of pollen studies in distinguishing some taxonomic groups in the Astereae.     

A NEW GENUS AND SPECIES OF NOCTUIDAE FROM CHINA(LEPIDOPTERA)

In this paper, a new genus and species of Noetuidae are reported. Type specimenis kept in the Institute of Zoology, Academia Sinica, Jingia, gen. nov. Proboscis fully developed; palpi obliquely porrect to just beyond frons, the 3rdjoint very short; frons with rounded prominence, with corneous plate below it; eyeslarge, rounded, naked; head and thorax elothed with hairs and few scales; fore tibiae     

DIFFERENTIAL SENSITIVITY OF “DOUBLE” AND “SINGLE” FLOWERS OF NIGELLA DAMASCENA (RANUNCULACEAE) TO EMASCULATION AND TO GA3

In Nigella damascena “double” flower is inherited as a single-gene recessive to “single” flower. Early emasculation of “double” flowers greatly inhibits gynoecium development and, to a lesser degree, development of sepals and bracts. No comparable inhibition of gynoecia was induced in “single” flowers though some sepal and bract inhibition was detected. A differential nutritional requirement for organ initiation on cultured flower apices was also detected. Apices of both varieties initiated stamens and carpels if kinetin was added to the basal medium. However, in the absence of kinetin, GA₃ was required for organ initiation in “doubles” but completely inhibited stamen initiation in “singles.” Both these differential effects are thought to reflect rather different patterns of gibberellin metabolism in the two genetic strains.     

2′-C-ALKOXY AND 2′-C-ARYLOXY DERIVATIVES OF N-(2-PHOSPHONOMETHOXYETHYL)-PURINES AND -PYRIMIDINES: SYNTHESIS AND BIOLOGICAL ACTIVITY

A series of novel, unusual type of acyclic phosphonate-based nucleotide analogues related to well-known antivirals (PMEA and HPMPA) was synthesized using easily available synthon. These compounds, which are distinguished for the presence of phosphonomethyl acetal linkage, form a group of derivatives that contribute to the understanding of structure-activity relationship within the area of acyclic nucleotide analogues.     

NEW SPECIES AND NEW RECORD OF DIPSOCOROMORPHA (HEMIPTERA:HETEROPTERA) FROM CHINA

Three species of Dipsocoromorpha found from China are reported in this paper.The type material of new species is preserved in the Shanghai Institute of Entomology,Shanhai, China excepting a part of the paratypes in collection of Nankai University,Tianjin, China.     

NOTES OF STENOPSOCIDAE AND ONE NEW GENUS AND SEVEN NEW SPECIES (PSOCOPTERA: PSOCOMORPHA) FROM SOUTH CHINA

This paper deals with one new genus and seven new species from South China. Akey is given to the species included, and Stenopsocus cubitalis Thornton, 1984 fromIndonesia is transferred to the new genus. Stenopsocidae originally included six genera, but Mockford (1978) transferredMatsumuriella Enderlein, 1906 and Taeniostigna Enderlein, 1901. and later Smithers(1990) transferred Kodamaus Okamota, 1907 to Amphipsocidae. The genus Epikodamaus     

TWO NEW GENERA, FOUR NEW SPECIES OF PLUSIINAE AND REVISION OF SOME OF ITS KNOWN SPECIES (LEPIDOPTERA: NOCTUIDAE)

This new genus is related to Arggrogramma Hubner and Acanthoplusia Dufy,but differs from them in the following characters: the stigma below the cell offore--wing stripe-shaped, long or short, white or grey, but never Y- or U-shapedand silvery, the valvae of male genitalia long and dilated at apex, and without     

SYNTHESIS AND PROPERTIES OF NOVEL TRIPHOSPHATE ANALOGUES: RIBONUCLEOSIDE AND DEOXYRIBONUCLEOSIDE (α-P-BORANO, α-P-THIO)TRIPHOSPHATES

The first ribo- and deoxyribo-nucleoside (α-P-borano, α-P-thio)triphosphates have been synthesized. The chemical and biochemical properties of adenosine (α-P-borano, α-P-thio)triphosphate and thymidine (α-P-borano, α-P-thio) triphosphate have been investigated.     

TWO NEW SPECIES OF MACROPHΥA DAHLBOM FROM SHAANXI AND GANSU OF CHINA (HYMENOPTERA, TENTHREDINIDAE)

记述采自中国陕甘南部的钩瓣叶蜂属2新种,杨氏钩瓣叶蜂Macrophya yangi Wei et Zhu,sp.nov.和晕翅钩瓣叶蜂Macrophya infuscipennis Wei et Li,sp. nov..新种模式标本保存于中南林业科技大学昆虫模式标本室.     

AUDIO COMPUTERS—THEORY OF OPERATION AND GUIDELINES FOR SELECTION OF SYSTEMS AND COMPONENTS

ABSTRACT

Computers are available that can store, synthesize and replay sounds using digital technology. I describe the major components of audio computers, the principles of digital sound acquisition and playback, and information and caveats for scientists interested in acquiring an audio computer system for their own use. A tutorial on analog filter application is also included as well as a diagnostic procedure and a buyer's check list.     

COMPARISON OF THE ANTIVIRAL ACTIVITY OF HYDROPHOBIC AMINO ACID PHOSPHORAMIDATE MONOESTERS OF 2′, 3′-DIDEOXYADENOSINE (DDA) AND 3′-AZIDO-3′-DEOXYTHYMIDINE (AZT)

A series of hydrophobic, water soluble and non-toxic amino acid phosphoramidate monoesters of dideoxyadenosine (ddA) and 3′-azido-3′-deoxythymidine were shown to inhibit the replication of HIV-1 in human peripheral blood mononuclear cells (PBMC) from two donors. The tryptophan methyl ester phosphoramidates of AZT and ddA were equally potent (EC₅₀S = 0.3–0.4 μM), while the phenyl methyl ester of ddA was 40- to 100- fold more potent than the AZT derivatives. The alaninyl methyl ester of AZT was found to be 70- fold more potent than the ddA derivative. The methyl amide derivatives were found to be 5–20 fold less active than the methyl esters for the ddA series, while for AZT the derivatives were found to be of similar potency or 60- to 166- fold more potent than the methylesters.     

NEW SPECIES AND SUBSPECIES OF THE GENUS ANOMALA FROM SHAANXI(Coleoptera, Rutelidae)

Anomala flavo femorata sp. nov. Length: 15-16mm, breadth : 8-8.5mm. Black brown, with a not very strong metallic lustre, lateral margins of prono-tum, a transverse zigzag band (sometimes broken into three spots) upon elytron,metathoracic episternum, a round spot on the side of each abdominal segment, entire