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Cytochrome caa3 (cytochrome oxidase) from the thermophilic bacterium PS3 can exhibit full catalytic activity in the presence of ascorbate and TMPD or other electron donors and in the absence of added soluble c-type cytochromes. It appears to possess only a low-affinity and not a high-affinity site for the soluble cytochromes. Proteoliposomal cytochrome caa3 develops an effective membrane potential in the presence of ascorbate and TMPD or PMS, in the absence of added soluble cytochrome c. Reduction of the a3 centre is blocked in the presence of cyanide. During reductive titrations of the cyanide-inhibited enzyme, electrons initially equilibrate among three centres, the c haem, the a haem and one of the associated Cu atoms. During steady-state turnover, electrons probably enter the complex via the bound c haem; the a haem and perhaps an associated CuA atom are reduced next. It is concluded that, despite its size and hydrophobic association with the aa3 complex, the haem c-containing subunit can behave in an analogous way to that of mammalian cytochrome c, bound at the high-affinity site of the eucaryotic enzyme. 相似文献
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第十三届国际光生物学大会 (13Th InternationalCongressonPhotobiology)由国际光生物学协会 (AssociationInternationaledePhotobiologie,AIP)主办 ,美国光生物学会承办 ,日本、韩国、欧洲光生物学会协办 ,于2000年7月1 -6日在旧金山举行。会议有1000多位科学家参加 ,全面介绍了光生物学各个学科的进展 ,及其在医学、环境、农业等领域的应用。会议共安排了10个大会报告 ,组织了55个专题会议 ,安排14场口头发言 ,3个时间段的墙报展… 相似文献
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G. Venema 《Cancer immunology, immunotherapy : CII》1990,31(3):196-196
Meeting announcement
15th International Cancer Congress 相似文献17.
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