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Fedorov MV 《Biofizika》2001,46(5):790-794
Two methods checking changes in time of histogram patterns were investigated. These methods are relied on discrete wavelet transform. The result is that in the some cases these methods can more effectively to examine latency in the behavior of histograms form constructed by on overlapping short segments of experimental data.  相似文献   

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The effects of a 30 week exercise programme on serum lipid values, blood pressure, and cardiac function were assessed in a group of sedentary men aged 35-50 training for their first marathon. Mean serum cholesterol concentration (n = 33) fell by 12% from 6.54 (SE 0.18) to 5.76 (0.15) mmol/l (mean fall 0.78 mmol/l; 95% confidence interval 0.52 to 1.04 mmol/l), serum triglyceride concentration (n = 33) by 22% from 1.56 (0.17) to 1.21 (0.09) mmol/l (mean fall 0.34 mmol/l; 95% confidence interval 0.12 to 0.56 mmol/l), and mean blood pressure (n = 27) by 10% from 102 (2) to 92 (2) mm Hg (mean fall 10 mm Hg; 95% confidence interval 7 to 13 mm Hg). These changes were not explained by changes in body composition. Peak exercise left ventricular end diastolic volume (n = 16) increased with training; as a result of this and an increased exercise left ventricular ejection fraction peak exercise cardiac output increased from 19.9 (1.2) to 23.1 (3.0) l/min (mean rise 3.2 l/min; 95% confidence interval 1.5 to 5.0 l/min). Maximum oxygen consumption increased from 33.9 (1.6) to 39.0 (1.3) ml/kg/min (mean rise 5.0 ml/kg/min; 95% confidence interval 1.8 to 8.2 ml/kg/min). This study showed favourable effects on coronary risk factors and cardiac function and supports the place of regular exercise in coronary prevention programmes.  相似文献   

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Recurrence risks are compared to conditional recurrence risks under certain association models corresponding to the underlying semi-symmetric intraclass contingency table. Ratios of mean squared errors are used to make the comparisons. A study of the comparisons corroborates the theory of KHAMIS and HINKELMANN (1984), and gives new insight into the disease-genotype association problem.  相似文献   

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A case of Varicella-zoster virus re-infection in a 3.5-year child with the acute lymphoblastic leukemia is presented. This report aims at emphasizing a possibility of re-activation of the virus in younger and younger children with immunodeficiency. A clinical course may imitate chicken-pox creating diagnostic problems.  相似文献   

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Recurrence of the cytochrome fold in a nitrate-respiring bacterium   总被引:4,自引:0,他引:4  
The crystal structure of cytochrome c550 (formerly MDC) from the oxygen or nitrate-respiring bacterium Micrococcus denitrificans has been determined to a resolution of four Ångstrom units. By comparison with the structures of eukaryotic cytochrome c and photosynthetic Rhodospirillum rubrumc2, the polypeptide chain path can be followed from one end of the protein to the other. Many aromatic side chains can be identified even at 4 Å. The same “cytochrome fold” is seen in all three redox proteins. Cytochrome c550 has the same insertions on the left-hand side of the molecule as c2 (in comparison with c), plus three more external additions and a changed right-hand side hairpin bend, which together account for approximately 25 residues. In terms of gross chain folding, c550 is more like c2 than c, but in its arrangement of aromatic residues in the righthand side channel, the two respiratory cytochromes c and c550 are most nearly alike. The similarities and differences in these three proteins support earlier suggestions concerning important and unimportant zones on the molecular surface, and lead to testable hypotheses about evolutionary descent. The cytochrome fold is the oldest common structure found to date among diverse proteins and may be a useful diagnostic tool in studying the process of protein evolution.  相似文献   

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Recurrence plots of neuronal spike trains   总被引:2,自引:0,他引:2  
The recently developed qualitative method of diagnosis of dynamical systems — recurrence plots has been applied to the analysis of dynamics of neuronal spike trains recorded from cerebellum and red nucleus of anesthetized cats. Recurrence plots revealed robust and common changes in the similarity structure of interspike interval sequences as well as significant deviations from randomness in serial ordering of intervals. Recurring episodes of alike, quasi-deterministic firing patterns suggest the spontaneous modulation of the dynamical complexity of the trajectories of observed neurons. These modulations are associated with changing dynamical properties of a neuronal spike-train-generating system. Their existence is compatible with the information processing paradigm of attractor neural networks.  相似文献   

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Summary The recurrence risks for Down syndrome due to an inherited translocation are estimated from empirical data in the literature for two maternal age groups: mothers under 30 and mothers 30 and over. These risks were found to be approximately 0.3% and 0.05%, respectively. The probability for two Down syndrome sibs both having an inherited translocation was estimated as about 18.2% for the former age group and 2.7% for the latter. The relative effectiveness in preventing Down syndrome births by karyotyping affected children is discussed.  相似文献   

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本文报道1例乳腺癌复发转移牙龈的诊断,提示乳腺癌的转移通常为区域淋巴结转移,也可经血液远处转移,最常见的远处转移部位为肺、肝、骨等,转移至牙龈的则十分罕见,牙龈上的转移癌早期表现与牙龈瘤极为相似,容易误诊。详细地询问病史极为重要,穿刺细胞学检查有助于明确诊断,必要时可以在术中冰冻活检,明确诊断后按一般恶性肿瘤的治疗原则手术治疗。  相似文献   

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