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During the 1940s, as part of its investigation of 'Communist Infiltration Into the Motion Picture Industry', the Federal Bureau of Investigation [FBI] borrowed criteria for determining if a motion picture contained communist propaganda from the Motion Picture Alliance for the Preservation of American Ideals [MPAPAI], a private, anti-communist organization located in Hollywood. An analysis of the FBI's interpretation of movies that featured black characters or explored racial themes reveals how the agency racialized its investigation of subversiveness in the early Cold War period. In the FBI's application of the MPAPAI criteria, blackness became synonymous with subversiveness and whiteness with Americanism. The FBI's racial project, as revealed in these reviews, is linked to its framing of the Communist threat and contrasted to the Truman administration's racial project and framing of the Communist threat  相似文献   

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Jasper Rine  Adam P. Fagen 《Genetics》2015,200(4):1015-1019
Scientific progress runs on the intellect, curiosity, and passion of its practitioners fueled by the research dollars of its sponsors. The concern over research funding in biology in general and genetics in particular led us to survey the membership of the Genetics Society of America for information about the federal support of genetics at the level of individual principal investigators. The results paint a mosaic of circumstances—some good, others not so good—that describes some of our present challenges with sufficient detail to suggest useful steps that could address the challenges.  相似文献   

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Cold treatment of surface sterilized explant material of hardwood trees at 4°C for two or four days reduced or eradicated internal contamination with Bacillus subtilis. This procedure provides a cheap, rapid and non-toxic technique to introduce material from adult trees, growing out of doors, into culture.  相似文献   

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It is more than half a century since Frederick G. G. Rose (1915–1991) published his classic text, The classification of kin, age structure and marriage amongst the Groote Eylandt Aborigines: A study in method and a theory of kinship (1960) in the former German Democratic Republic. Although the fieldwork for his thesis had been carried out in Australia on Groote Eylandt in 1938 and 1941, a conservative academic establishment and the political climate of the Cold War postponed its publication until 1960. Why were Rose's fieldwork findings suppressed by the powerful gate-keeper of Australian anthropology, Professor Adolphus Peter Elkin (1891–1979)? Moreover, why was Rose later denied a government permit to revisit Groote Eylandt and Central Australia to further his research? This paper examines the early work of the communist anthropologist, Frederick Rose, within the broad context of Western post-war anthropological developments, an expanding capitalist economy and the political tensions of the Cold War era. As a communist and public servant from 1938 to 1954, Rose was forced, after the Petrov Royal Commission cast him under a cloud of suspicion, to seek institutional support for his academic career in the German Democratic Republic.  相似文献   

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Objective: At present, rodents represent the most common animal model for research in obesity and its comorbidities (e.g., type 2 diabetes and coronary heart disease), however, there are several physiological and developmental differences between rodents and humans reflective of their relatively ancient evolutionary divergence (approximately 65 to 75 million years ago). Therefore, we are currently developing the baboon as a nonhuman primate model for the study of the genetics of obesity. Research Methods and Procedures: At present, we are collecting extensive phenotypic data in a large pedigreed colony (N > 2000) of baboons housed at the Southwest Foundation for Biomedical Research in San Antonio, Texas. The long‐term goal of this project is to identify genes influencing adiposity‐related phenotypes and to test hypotheses regarding their pleiotropic effects on other phenotypes related to increased risk for a variety of common diseases (e.g., coronary heart disease and type 2 diabetes). Results: To date we have obtained various adipose‐specific endocrine measures, adipose tissue biopsies, and estimates of body composition on a substantial portion of our pedigreed colony. The pattern of adipose tissue accumulation follows closely that seen in humans, and we have detected significant additive genetic heritabilities for these obesity‐related phenotypes. Discussion: Given the physiological and developmental similarities between humans and baboons, along with the ability to collect data under well‐controlled situations and the extensive pedigree data available in our colony, the baboon offers an extremely valuable nonhuman primate model for the study of obesity and its comorbidities.  相似文献   

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The Japanese encephalitis virus (JEV), an arthropod-born Flavivirus, is the major cause of viral encephalitis, responsible for 10,000–15,000 deaths each year, yet is a neglected tropical disease. Since the JEV distribution area has been large and continuously extending toward new Asian and Australasian regions, it is considered an emerging and reemerging pathogen. Despite large effective immunization campaigns, Japanese encephalitis remains a disease of global health concern. JEV zoonotic transmission cycles may be either wild or domestic: the first involves wading birds as wild amplifying hosts; the second involves pigs as the main domestic amplifying hosts. Culex mosquito species, especially Cx. tritaeniorhynchus, are the main competent vectors. Although five JEV genotypes circulate, neither clear-cut genotype-phenotype relationship nor clear variations in genotype fitness to hosts or vectors have been identified. Instead, the molecular epidemiology appears highly dependent on vectors, hosts'' biology, and on a set of environmental factors. At global scale, climate, land cover, and land use, otherwise strongly dependent on human activities, affect the abundance of JEV vectors, and of wild and domestic hosts. Chiefly, the increase of rice-cultivated surface, intensively used by wading birds, and of pig production in Asia has provided a high availability of resources to mosquito vectors, enhancing the JEV maintenance, amplification, and transmission. At fine scale, the characteristics (density, size, spatial arrangement) of three landscape elements (paddy fields, pig farms, human habitations) facilitate or impede movement of vectors, then determine how the JEV interacts with hosts and vectors and ultimately the infection risk to humans. If the JEV is introduced in a favorable landscape, either by live infected animals or by vectors, then the virus can emerge and become a major threat for human health. Multidisciplinary research is essential to shed light on the biological mechanisms involved in the emergence, spread, reemergence, and genotypic changes of JEV.  相似文献   

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Incubation of rat-liver microsomes, previously azide-treated to inhibit catalase, with H2O2 caused a loss of cytochrome P-450 but not of cytochrome b5. This loss of P-450 was not prevented by scavengers of hydroxyl radical, chain-breaking antioxidants or metal ion-chelating agents. Application of the thiobarbituric acid (TBA) assay to the reaction mixture suggested that H2O2 induces lipid peroxidation, but this was found to be due largely or completely to an effect of H2O2 on the TBA assay. By contrast, addition of ascorbic acid and Fe(III) to the microsomes led to lipid peroxidation and P-450 degradation: both processes were inhibited by chelating agents and chain-breaking antioxidants, but not by hydroxyl radical scavengers. H2O2 inhibited ascorbate/Fe (III)-induced microsomal lipid peroxidation, but part of this effect was due to an action of H2O2 in the TBA test itself. H2O2 also decreased the colour measured after carrying out the TBA test upon authentic malondialdehyde, tetraethoxypropane, a DNA-Cu2+/o-phenanthroline system in the presence of a reducing agent, ox-brain phospholipid liposomes in the presence of Fe(III) and ascorbate, or a bleomycin-iron ion/DNA/ascorbate system. Caution must be used in interpreting the results of TBA tests upon systems containing H2O2.  相似文献   

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The paper examines the impact of genetic research on the religious identity of the Bene Israel Indian Jewish community and the Lemba Judaising group of southern Africa. It demonstrates how DNA tests which happened to support the possibility of the communities' legends of origin affected their self-perception, the way they are viewed by their neighbors, and their image in the West. It is argued that in both cases what accounted most for the Bene Israel and Lemba responses to the tests was the way the results were portrayed in the mass media, the history of the development of Judaism in their communities, and the local realities.  相似文献   

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Tanya Richardson 《Ethnos》2016,81(1):125-151
Between 1976 and 1980, a Soviet agro-industrial project turned the Sasyk estuary in southern Ukraine into a freshwater irrigation reservoir. While the project failed to produce irrigable water, it had many negative environmental consequences. Despite two decades of activism, this water body persists in its freshwater state. To understand how this situation persists, resources need to be conceived as materialities emergent in and distributed across assemblages of human and nonhuman elements rather than pre-existing substances. This move helps reveal a politics of multiplication that has enabled officials to sustain the resource potential of Danube–Dnister Irrigation System waters. As recognition of Sasyk as polluted and valueless increased, officials mobilized linkages that consolidated Sasyk as a fish reservoir, and its main canal as irrigable and drinking water, thereby stymieing activists' restoration campaign.  相似文献   

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Biologists routinely use molecular markers to identify conservation units, to quantify genetic connectivity, to estimate population sizes, and to identify targets of selection. Many imperiled eagle populations require such efforts and would benefit from enhanced genomic resources. We sequenced, assembled, and annotated the first eagle genome using DNA from a male golden eagle (Aquila chrysaetos) captured in western North America. We constructed genomic libraries that were sequenced using Illumina technology and assembled the high-quality data to a depth of ∼40x coverage. The genome assembly includes 2,552 scaffolds >10 Kb and 415 scaffolds >1.2 Mb. We annotated 16,571 genes that are involved in myriad biological processes, including such disparate traits as beak formation and color vision. We also identified repetitive regions spanning 92 Mb (∼6% of the assembly), including LINES, SINES, LTR-RTs and DNA transposons. The mitochondrial genome encompasses 17,332 bp and is ∼91% identical to the Mountain Hawk-Eagle (Nisaetus nipalensis). Finally, the data reveal that several anonymous microsatellites commonly used for population studies are embedded within protein-coding genes and thus may not have evolved in a neutral fashion. Because the genome sequence includes ∼800,000 novel polymorphisms, markers can now be chosen based on their proximity to functional genes involved in migration, carnivory, and other biological processes.  相似文献   

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