Studies on the Chemical Constituents of Rourea microphylla (Hook. et Arn) Planch.

Eleven compounds were isolated from the twigs and leaves of Rourea microphylla (Hook. et Arn) Planch. They were identified as quercetin-3-O-α-L-rhamnopyranoside (Ⅰ), hyperin (Ⅱ), quercetin (Ⅲ), astilbin (Ⅳ), β-sitosterol (Ⅴ), β-sitosteryl-β-D-glucopyranoside (Ⅵ), physcion (Ⅶ), erythroglaucin (Ⅷ), stearic acid (Ⅸ), palmitic acid (Ⅹ) and n-nonacosanane (Ⅺ) respectively, by means of UV, IR, NMR, MS spectra analyses and through chemical methods. The compounds Ⅰ, Ⅱ, Ⅲ, Ⅳ, Ⅵ, Ⅶ, Ⅷ, Ⅸ, Ⅹ and Ⅺ were first reportedin the Rourea genus.     

Studies on the Alkaloids of Stephania succifera Lo. et Tsoong

Eleven alkaloids were isolated from roots of Stephania succifera Lo et Tsoong. They were identified as crebanine (Ⅰ), tetrahydropalmatine (Ⅱ), dehydrocrebanine (Ⅲ), palmatine (Ⅳ). dehydrocorydalmine (Ⅴ), crebanine nitrate (Ⅵ), oxocrebanine (Ⅶ), corydalmine (Ⅷ), phanostenine (Ⅸ), discretamine (Ⅹ) and corypalmine (Ⅺ) by means of TLC. UV, NMR MS spectral analyses and the fact that no depression of MP. with authentic samples was observed. Compounds Ⅳ, Ⅴ, Ⅵ, Ⅶ, Ⅸ, Ⅹ and Ⅺ were first reported from this plant.     

The Chemical Constituents of Antitumor from Sabina vulgaris Ant

Eleven known compounds, transcommunic acid (Ⅰ), cis-communic acid (Ⅱ), sandaracopimaric acid (Ⅲ), isocupressic acid (Ⅳ), sugiol (Ⅴ), 12-hydroxy-6, 7-seco- abieta-8, 11, 13-triene 6, 7-dial (Ⅵ), β-peltatin-A-methyl ether (Ⅶ), bergaptin (Ⅷ), β-sitosterol (Ⅹ), lignoceric acid (Ⅺ), cerotic acid(Ⅻ) and a new 3, 4-benzocumarins sabilactone (Ⅸ) were newly isolated from the bark of Sabina vulga ris Ant. (= Juniperus sabina L.). Their structures were determined from spectra data and chemical evidence. Compounds Ⅳ–Ⅹ were first isolated from this plant. The bioassay results showed that compounds Ⅰ–Ⅳ, Ⅵ andⅦ were shown to be cytotoxic effects for P-388 leukemia cell in vitro.     

Separation and Identification of Chemical Constituents of Dysosma majorense(Gagn.)Hsiao et Y. H. Chen,nov comb

Ten compounds, namely physcion (Ⅰ), podophyllotoxone (Ⅱ), isopicropodophyllone (Ⅲ), picropodophyllone (Ⅳ), 4'-demethyl-podophyllotoxone (Ⅴ), dehydropodo- phyllotoxin (Ⅵ), diphyllin (Ⅶ), picropodophyllin (Ⅷ), podophyllotoxin (Ⅸ) and 4'-demethylpodophyllotoxin (Ⅹ), were separated from Dysosma majorense (Gagn.) Hsiao et Y. H. Chen, nov comb. Compound Ⅳ was first isolated from natural source and anthraquinone Ⅰ was first isolated from genus Dysosma. Ⅴ, Ⅷ and Ⅹ showed strong acttve inhibited against P388.     

Chemical Constituents of Glycyrrhiza eurycarpa P. C. Li (1I)

Huang Gancao (Glycyrrhiza eurycarpa P. C. Li) is a new species discovered recently. Its chemical constituents have not been reported before. This paper reports the isolation of ten components (Ⅰ—Ⅹ) from its roots and rhizomes collected in Jinta County, Gansu Province. On the basis of physico-chemlcal constants and spectroscopic (IR, UV, 1HNMR, 13CNMR, MS, and CD) analysis, they were identified as ononin(Ⅰ), liquiritigenin 4 -O-β-D-apio-D-franosyl-(1 →2)-β-D-glucopyranoside(II), isoliquiritigenin-4-O-β-D-apio-D-franosyl-(1→ 2) β-D-glucopyranoside (Ⅲ), choerospondin (Ⅳ), violanthin (Ⅴ), isoviolan thin (Ⅵ), vicenin-2(Ⅶ), uralsaponin A(Ⅷ), daucosterol (Ⅸ), and phloretic acid (Ⅹ), respectively All of them were isolated from this plant for the first time. Choerospondin, violanthin, daucosteroi and phloretic acid were not found in this genus before.     

The Chemical Constituents of Elsholtzia ciliata (Thund.) Hyland

Fourteen compounds have been obtained from the Elsholtzia ciliata (Thund.) Hyland. Their structures were identified by spectral and chemical methods as following: Ⅰ. 6-methyl-tritriacontane, Ⅱ. 13-cyclohexyl-hexoacosane, Ⅲ. β-sitosterol, Ⅳa. palmitic acid, Ⅳb. linoleic acid, Ⅳc. linolenic acid, Ⅴ. ursolic acid, Ⅵ. 5-hydroxy--6, 7-dimethoxyflavone, Ⅶ. 5-hyd-foxy-7, 8-dimethoxyflavone, Ⅷ. 5,7-dihydroxy-4'-methoxyflavone, Ⅸ. 5-hydroxy-7,4'-dime-thoxyflavone, Ⅹ.β-sitosterol-β-D-glucoside, Ⅺ. 5-hydroxy-6-methylflavanone-7-O-α-D-galacopy-ranoside, Ⅻ. acacetin-7-O-β-glucoside. Among all the compounds, Ⅺ is a new compound. Except for Ⅳb and Ⅳc, the other twelve compounds were first found in this plant.     

The Chemical Constituents from Cynanchum Komarovii Al. Ilinski

Ten compounds were isolated from the roots and stems of Cynanchum komarovii Al. Iljinski. They were identified as 7-demethoxylophorine (Ⅰ), epi-alnusenol (Ⅱ), β-sitosterol (Ⅲ), triacontanolic acid (Ⅳ), sucrose (Ⅴ), desoxytylophorinin N-oxide (Ⅵ), apocynine (Ⅶ), paeonol (Ⅷ), β-sitosteryl-β-D-glucopyranoside (Ⅸ) and glucose (Ⅹ) by means of UV, IR, NMR, MS spectral analyses and through chemical methods. These compounds were first reported in this plant. One of them, Ⅵ is a new alkaloid. The bioassay results showed that the compounds Ⅰ, Ⅵ and reaction product Ⅺ exhibited cytotoxic effects to P-388 leukemia cell in vitro. Ⅺ is also a new compound.     

Studies on the Alkaloids of Stephania yunnanensis

Ten known alkaloids, sinoacutine (Ⅰ), 1-tetrahydropalmatine (Ⅱ), d-stepharine (Ⅲ), 1- stepholidine (Ⅳ), 1-corydalmine (Ⅴ), stephanine (Ⅵ), palmatine (Ⅶ), dehydrocorydalmine (Ⅷ), stepharanine (Ⅸ) and roemerine (Ⅹ) were isolated from the roots of Stephamia yunnanensis H. S. Lo. Their structures were determined from spectral data and chemical evidence.     

银杏中种皮化学成分的分离及鉴定

银杏（Ginkgo biloba Linn．）在中国种植广泛,其产量占全世界总产量的70％[1]。中药白果仁是银杏种子去除肉质外种皮和骨质中种皮后得到的,具有敛肺定喘、止带缩尿的功效。目前,有关银杏种子的研究主要集中在具有药食同源的白果仁[2]及具有潜在应用价值的外种皮[3]上,鲜见对银杏种子中种皮的研究报道。生产中大量的银杏中种皮被废弃,因此,开展银杏中种皮的相关研究对于充分利用该类资源非常必要。鉴于此,作者对银杏中种皮的化学成分进行了系统分析,以期为其开发应用提供参考依据。     

小叶黄杨化学成分的研究

小叶黄杨氯仿组分通过硅胶柱色谱分离纯化,从中分离得到9个化合物,分别鉴定为:β-谷甾醇(β-Sitosterol,Ⅰ)、豆甾醇(Stigmasterol,Ⅱ)、胡萝卜甙(daucosterol,Ⅲ)、水杨酸(salicylis acid,Ⅳ)、香草酸(vanillicacid,Ⅴ)、5,4′-二羟基-3,3′,7-三甲氧基-黄酮(5,4′-dihydroxy-3,3′,7-trimethoxy-flavone,Ⅵ)、5,4′-二羟基-3,3′,6,7-四甲氧基-黄酮(5,4′-dihydroxy-3,3′,6,7-tetramethoxy-flavone,Ⅶ)、Cleomiscosin A(Ⅷ)、3,5-二羟基-4′,6,7-三甲氧基-黄酮-3′-O-β-D-葡萄糖甙(3,5-dihydroxl-4′,6,7-trimethoxyl-flavone-3′-O-β-D-glucopyranoside,Ⅸ),其中化合物Ⅳ、Ⅴ、Ⅵ、Ⅶ均首次从该属植物中分离得到。     

The Chemical Principles from the Female lnftorescences of Typha angustata

Seven crystalline compounds have been isolated from the female inflorescences of Typha angustata Bory et Chaub. They were identified as vanillic acid (Ⅰ), E-p-hydroxy- cinnamic acid (Ⅱ), Protocatechuic acid (Ⅲ), E-Pro-penoic acid-3- (4-hydroxyphenyl)- 2,3-dihydrohypropyl ester (Ⅳ), Succinic acid (Ⅴ), p-hydroxybenzaldehyde (Ⅵ) and D-mannitol (Ⅶ). (Ⅳ) is a new compound. (Ⅰ), (Ⅱ), (Ⅲ) and (Ⅶ) were attained for the first time from Typhaceae.     

贵州紫云产黄花香茶菜的化学成分研究

采用甲醇回流提取和硅胶柱层析方法,从紫云产黄花香茶菜中分离得到6个化合物,结合1H-NMR、13C-NMR数据及文献资料鉴定为黄花香茶菜乙素(Ⅰ)、黄花香茶菜丁素(Ⅱ)、大萼变型香茶菜甲素(Ⅲ)、3β-Hydroxy-18α,19α-urs-20-en-28-oic acid(Ⅳ)、齐墩果酸(Ⅴ)和熊果酸(Ⅵ)。其中化合物Ⅳ为首次从该属植物中分离得到。     

Isolation and Identification of Steroidal Sapogenins from Rhizome of Dioscorea septemloba Thunb

Five components were isolated from acid-treated rhizome of D. septemloba Thunb. Their structures, the were identified as diosgenin (Ⅰ), β-sitosterol (Ⅱ), palmitic acid (Ⅲ), diosgenin palmitate (Ⅳ) and △3,5-deoxytigogenin (Ⅴ) on the basis of physical constants and spectral data.     

Studies on Active Constituents of Root of Euphorbia ebracteolata Hayata Euphorbiaceae

Seven crystalline constituents were obtained from acidic alcoholic extract of root of Euphorbia ebracteolata. They were identified as octacosanoic acid, daucosterol, β-sitosterol, bis (5-formyl-furfuryl)-ether (Ⅳ), a triterpenic acid, 2,4-dihydroxy-6-methoxyl-3-methyl-acetoph-enone (Ⅵ) and 2-β-glucoside of (Ⅵ) respectively. Three of them (Ⅳ, Ⅴ and Ⅵ) revealed inhibitory effect against tuberculous bacillus..In this paper, the authors reported identification of compound Ⅳ which was found in this plant first time. Its extract has a remarkable effect for the treatment of tuberculosis.     

Studies on the Chemical Constituents of Pyrus Communis

An aqueous extract of the twigs of Pyrus communis L. var. sativa (DC) DC. showed inhibitory effect against S-180. Compounds were isolated from the twigs of P. communis and eight of them were identified as nonacosane (Ⅰ), lupeol (Ⅲ), β-sitosterol (Ⅳ), betulin (Ⅴ), betulinic acid (Ⅵ), daucosterol (Ⅶ), hydroquinone (Ⅷ) and arbutin (Ⅸ) by MS, NMR, IR, UV and some chemical techniques. It was showed that the compounds Ⅲ, Ⅳ, Ⅴ, Ⅵ, Ⅷ and Ⅸ possessed some bacteriostatic activities on Escherichia coli, Salmonella typhi, Shigclla flexneri and Staphylococus aureus. Primary pharmacology tests showed that Ⅷ had inhibitory effect against S-180 (47.5%).     

The Chemical Constituents of Duzhong (The Bark of Eucommia ulmoides Oilv.)

Seven constituents have been isolated from the bark of Eucommia ulmoides Oliv. Based on spectral analysis and determination of Physico-chemical constants they have been identified as: nonacosane (Ⅰ), n-triacontanol (Ⅱ), β-sitosterol (Ⅲ), betulin (Ⅳ), betulic acid (Ⅴ), ursolic acid (Ⅵ), vanillic acid (Ⅶ).     

Studies on the Chemical Constituents of Xylanche himalaica

Six compounds were isolated from the tuber of Xylanche himalaica (Hook. f. et Thorns.) G. Beck Based on the physico-chemical constants, spectral analysis (IR, MS, 1H-NMR, 13C-NMR)and preparation of the derivative, they were identified as 3-epi-acetoxyurs-12-en-28-al (Ⅰ), ursolic acid (Ⅱ), 3-epi-ursolic acid (Ⅲ), (+)-pinoresinol (Ⅳ), (+)-pinoresinol monoglucoside (Ⅴ) and daucosterol (Ⅵ). Ⅰis a new compound.     

丽江蚤缀的化学成分

利用DiaionHP20及硅胶柱层析进行化合物的分离,从乙酸乙酯萃取部位分离得到了8个化合物,借助多种光谱技术进行结构鉴定分别鉴定为E对甲氧基肉桂酸(pEMethoxycinnamicacid)(Ⅰ),Z对甲氧基肉桂酸甲酯(3(4Methoxyphenyl)2Zpropenoicacidmethylester)(Ⅱ),Z对甲氧基肉桂酸(pZMethoxycinnamicacid)(Ⅲ),E对羟基肉桂酸甲酯(pEHedroxycinnamicacidmethylester)(Ⅳ),2,4,6,4′fourhydroxydihydrochalcone(Ⅴ),5,7,4′三羟基3′,5′二甲氧基黄酮(Ⅵ),β谷甾醇(βSidosterol)(Ⅶ),胡萝卜苷(Daucosterol)(Ⅷ)。所有化合物均为已知化合物,并首次从该植物中分得。     

The Chemical Constituents from Dracocephalum tanguticum Maxim.

Dracocephalum tanguticum Maxim. is endemic in Qinghai-Tibetan Plateau. It has been widely used in Tibetan traditional medicine. From the methanol extracts of this species, eight compounds were isolated and identified as oleanolic acid ( Ⅰ ), ursolic acid ( Ⅱ ), daucosterol (Ⅲ), skimmin (Ⅳ), eosmosiin (Ⅴ), pedalitin (Ⅵ), pedaliin (Ⅶ), and a new natural product pedaliin-6″-acetate ( ⅩⅢ ).     

Two New Taxane Diterpenoids from Taxus yunnanensis

Five compounds were isolated from the bark of Taxus yunnanensis Cheng et L. K. Fu. Based on spectral IR, MS, 1H-NMR, 13C-NMR and physico-chemical constant analysis, they were identified as 7-epi-taxol B ( Ⅰ ), 1, 13-diacetoxy-10-deacetyl baccatin Ⅲ (Ⅱ ), taxol C-7-xylose (Ⅲ), taxol (Ⅳ), 3-epi-ursolic acid (Ⅴ). Compounds Ⅰ and Ⅱ were newly identified.