偏翅唐松草化学成分的研究

从偏翅唐松草（Thalictrum delavayi Franch.)的乙醇提取物的氯仿部分分离到9个化合物（1-9）。其中化合物1和2为新化合物,分别为5-hydro-N-methylcorydalidine(1)和1-（4-methoxybenzyl)-2-N-methyl-6-hydroxyl-5,7-dimethoxy-isoquinoline(2)。化合物7为首次从唐松草属中分离到,它们的结构经波谱方法（包括HMQC和HMBC）得到鉴定。     

偏翅唐松草化学成分的研究

从偏翅唐松草(Thalictrum delavayi Franch.)的乙醇提取物的氯仿部分分离到9个化合物(1-9).其中化合物1和2为新化合物,分别为5-hydro-N-methylcorydalidine (1)和1-(4-methoxybenzyl)-2-N-methyl-6-hydroxyl-5,7-dimethoxy-isoquinoline (2).化合物7为首次从唐松草属中分离到.它们的结构经波谱方法(包括HMQC和HMBC)得到鉴定.     

江苏唐松草属(毛茛科)一新变种——珠芽华东唐松草

记载了中国江苏宝华山唐松草属一新变种——珠芽华东唐松草Thalictrum fortunei S. Moore var. bulbiliferum B. Chen &; X. J. Tian。该变种在花谢之后在大部分叶腋处形成一枚直径3-10 mm的珠芽,明显区别于原变种。     

滇产偏翅唐松草化学成分

提取、分离纯化并通过波谱方法鉴定了滇产偏翅唐松草 (ThalictrumdelavayiFranch)中 7个化合物 ,它们为 :3,4 二氢 6 ,7 二甲氧基异喹诺酮 (1) ,N 甲基紫堇碱 (2 ) ,6 ,7 二甲氧基 2 甲基异喹诺酮(3) ,Thalactamine(4) ,小檗碱 ,(5 ) ,4 (4 甲氧基苯基 ) 3 丁烯 2 酮 (6 ) ,降氧白毛茛分碱 (7) ,其中化合物(7)首次从唐松草属中分离得到。     

唐松草属五新种

该文描述了毛茛科唐松草属五新种:(1)小花唐松草,发现自贵州东北部,与多枝唐松草近缘,区别为其小叶较小,雄蕊较少,花丝较短,呈狭条形。(2)新宁唐松草,发现自湖南南部,与爪哇唐松草近缘,区别为本种的雄蕊花丝呈狭条状棒形,花只含3~6枚心皮。(3)短蕊唐松草,发现自河南东南部,在体态上与爪哇唐松草十分相似,区别为本种的雄蕊很短,花丝呈丝形,花只含4~6枚心皮。(4)毛蕊唐松草,发现自四川北部,与长柄唐松草有密切的亲缘关系,区别为本种的茎和花梗被短柔毛,萼片被缘毛,花药不具短尖头,子房密被短柔毛。(5)小金唐松草,发现自四川西部,与白茎唐松草在亲缘关系上甚为相近,区别为本种的小叶被微硬毛,雄蕊花丝呈狭条形,花药顶端无短尖头或具极小短尖头,心皮较小,长仅2.4 mm,柱头无翅。     

中国唐松草属植物的化学系统学初探

本文根据唐松草植物所含化学成分并结合其外部形态及地理分布对属内各群的亲缘关系进行了 探讨。结果表明：(1)从化学系统学角度看,中国植物志中所安排的属内各组植物间的关系是适宜的。(2)植物中所含生物碱的种类及含量与植物的进化有一定关系。在较原始的组中,成分的类型和含量相对较少;而在较进化的组中,各种结构类型得到较大发展。(3)唐松草属在毛茛科中有较特殊的地位。在科内,它是联系蓇葖果和瘦果植物群的过渡类群;在科外,它使毛茛科与小檗科、防己科和罂粟科发生联系,使其成为一个自然的分类群。     

唐松草属六新种

描述了毛茛科唐松草属六新种:(1)大关唐松草,发现自云南东北部,与多枝唐松草甚为近缘,区别为其小叶较厚,较大,多呈卵形或宽卵形,心皮花柱较短,稍向后弯曲,瘦果呈新月形。(2)宽柱唐松草,发现自甘肃南部,其特征为心皮花柱扁平,近长圆形,腹面无柱头或柱头组织,据此特征可与此属中国其他种区别。(3)六脉萼唐松草,发现自四川中部,与白茎唐松草近缘,区别为其茎和小叶有毛,萼片具六条脉,一些雄蕊的花药败育,子房被短柔毛,柱头无翅。(4)吉隆唐松草,发现自西藏南部,与白茎唐松草甚为近缘,区别为小托叶卵形、急尖,复单歧聚伞花序一条顶生,无侧生者,雄蕊花药呈狭长圆形,顶端钝,无短尖头。(5)螺柱唐松草,发现自云南西北部,可能与白茎唐松草有亲缘关系,区别为其萼片具1条脉,花有4~5枚雄蕊,心皮花柱顶部螺旋状弯曲,柱头不明显。(6)札达唐松草,发现自西藏西南部,与多叶唐松草近缘,区别为其小叶顶端急尖,边缘具尖牙齿,聚伞圆锥花序具少数分枝和少数花,萼片狭卵形,花药狭长圆形。     

黄皮种子中酰胺类生物碱及其杀线虫活性研究

为了解黄皮种子中的酰胺类生物碱及其杀线虫活性,运用多种色谱学及波谱学方法分离并鉴定了10个酰胺类生物碱,分别为:N-甲基桂皮酰胺(1),clausenalansamide A(2),3-dehydroxy-3-methoxyl-clausenalansamide A(3),clausenalansamide B(4),黄皮新肉桂酰胺B(5),N-(2-苯乙基)肉桂酰胺(6),2′-dehydroxy-2′-oxo-clausenalansamide B(7),lansamide-7(8),homoclausenamide(9),1,5-dihydro-5-hydroxy-1-methyl-3,5-diphenyl-2H-pyrrol-2-one(10)。其中,化合物3,7,10为新天然产物。首次对黄皮种子中的酰胺类生物碱2~8进行全齿复活线虫致死活性的测试,发现所测化合物均有致死活性,其中,化合物2,3,5和8有较强的致死活性,且均优于阳性对照除线磷,可为相关农药的研发提供科学依据。     

珙桐枝皮中的生物碱甙成分研究

从珙桐枝皮甲醇提取物的水溶性部分得到3个配糖体化合物,经核磁共振和质谱等光谱分析鉴定为1个喹啉类生物碱甙-pumiloside(1)和2个吲哚类生物碱甙-vincosamide(2),strictosidinic acid(3),其中pumiloside是抗肿瘤物质喜树碱的一种生物合成前体,这3个化合物均为首次从该植物中分得。     

四川毛茛科二新种——乌头属一新种和唐松草属一新种

该文描述了自四川西部发现的毛茛科二新种,包括四川乌头属一新种,即泸定乌头(Aconitum ludingense W.T.Wang),此新种隶属于乌头属乌头亚属,以及四川唐松草属一新种,即狭药唐松草(Thalictrum stenantherum W.T.Wang),给出了此新种与其近缘种六脉萼唐松草之间的形态区别.     

Recent advances in the study of Kaposi's sarcoma-associated herpesvirus replication and pathogenesis

It has now been over twenty years since a novel herpesviral genome was identified in Kaposi's sarcoma biopsies. Since then, the cumulative research effort by molecular biologists, virologists, clinicians, and epidemiologists alike has led to the extensive characterization of this tumor virus, Kaposi's sarcoma-associated herpesvirus(KSHV; also known as human herpesvirus 8(HHV-8)), and its associated diseases. Here we review the current knowledge of KSHV biology and pathogenesis, with a particular emphasis on new and exciting advances in the field of epigenetics. We also discuss the development and practicality of various cell culture and animal model systems to study KSHV replication and pathogenesis.     

The structure, reproduction and taxonomy of Vidalia and Osmundaria (Rhodophyta, Rhodomelaceae)

Comprises species occurring mostly in subtidal habitats in tropical, subtropical and warm-temperate areas of the world. An analysis of the type species, V. spiralis (Sonder) Lamouroux ex J. Agardh, a species from Australia, establishes basic characters for distinguishing species in the genus. These characters are (1) branching patterns of thalli, (2) flat blades that may be spiralled on their axis, (3) width of the blade, (4) primary or secondary derivation of sterile and fertile branchlets and (5) position of sterile and fertile branchlets on the thalli. Application of the latter two characters provides an important basic method for separation of species into three major groups. Osmundaria , a genus known only in southern Australia, was studied in relation to Vidalia , and its separation from the Vidalia assemblage is not accepted. Species of Vidalia therefore are transferred to the older genus name, Osmundaria. Two new species, Osmundaria papenfussii and Osmundaria oliveae are described from Natal. Confusion in the usage of the epithet, Vidalia fimbriala Brown ex Turner has been clarified, and Vidalia gregaria Falkenberg, described as an epiphyte on Osmundaria pro/ifera Lamouroux, is revealed to be young branches of the host, Osmundaria prolifera.     

New or rare chromosome counts in Artemisia L. (Asteraceae, Anthemideae) and related genera from Kazakhstan

Fifteen chromosome counts of six Artemisia taxa and one species of each of the genera Brachanthemum, Hippolytia, Kaschgaria, Lepidolopsis and Turaniphytum are reported from Kazakhstan. Three of them are new reports, two are not consistent with previous counts and the remainder are confirmations of very scarce (one to four) earlier records. All the populations studied have the same basic chromosome number, x = 9, with ploidy levels ranging from 2x to 6x. Some correlations between ploidy level, morphological characters and distribution are noted.     

肝癌中HBV和HCV基因和抗原的分布及意义

采用原位分子杂交方法检测HCV RNA及HBV X基因;采用免疫组织化学方法研究HCV核心抗原,非结构区C33c抗原及HBxAg在肝细胞肝癌中的定位及分布.结果表明(1)HCV RNA、HBV X基因在肝细胞肝癌组织检出率分别为40%(55/136)和82%(112/136).HCV RNA定位于癌细胞的胞浆内,阳性细胞呈散在、灶状及弥漫分布三种形式;HBV X基因在肝癌细胞中的分布呈胞浆型、核型及核浆型,阳性细胞也呈上述三种分布形式;(2)HCV C33c抗原、核心抗原在肝细胞肝癌中的阳性率为81%(133/164)及86%(141/164).C33c抗原定位于癌细胞及肝细胞的胞浆内;核心抗原既定位于癌细胞核中,又可定位于胞浆中.C33c抗原阳性细胞以灶状分布为主;而核心抗原阳性细     

Selection with two alleles and complete dominance

For a plant selection model with frequency-independent viabilities, fertilities and selfing rates, it is shown that apart from global fixation, for certain parameter combinations a protected polymorphism and facultative fixation (either allele may become fixed according to initial frequencies) may both occur. Facultative fixation requires different selling rates for the dominant and recessive type. Protection of the polymorphism requires resource allocation for male and female function. In this connection the problem of purely genetically caused population extinction is discussed.
For general frequency dependence and regular segregation, the chances for establishment of a completely recessive gene are compared to those of a completely dominant gene. It is proven that the process of establishment of the recessive gene, despite a fitness advantage, may be considerably endangered by drift effects if random mating prevails. The recessive gene may reach the same effectivity in establishment as a dominant gene, only if the recessive homozygote mates exclusively with its own type during the period of establishment.