Roseburia spp. Abundance Associates with Alcohol Consumption in Humans and Its Administration Ameliorates Alcoholic Fatty Liver in Mice

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Bat ASC2 suppresses inflammasomes and ameliorates inflammatory diseases

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Translation of GGC repeat expansions into a toxic polyglycine protein in NIID defines a novel class of human genetic disorders: The polyG diseases

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Solid-state NMR studies of amyloids

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Cryo-EM structures of human fucosidase FucA1 reveal insight into substrate recognition and catalysis

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The structural heterogeneity of α-synuclein is governed by several distinct subpopulations with interconversion times slower than milliseconds

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Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation

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Structural and functional properties of mSWI/SNF chromatin remodeling complexes revealed through single-cell perturbation screens

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Chimeric efferocytic receptors improve apoptotic cell clearance and alleviate inflammation

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Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays

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Cytoplasmic pool of U1 spliceosome protein SNRNP70 shapes the axonal transcriptome and regulates motor connectivity

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Bi-allelic LETM1 variants perturb mitochondrial ion homeostasis leading to a clinical spectrum with predominant nervous system involvement

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Gut microbes impact stroke severity via the trimethylamine N-oxide pathway

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Disease-linked mutations cause exposure of a protein quality control degron

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Self-Organizing 3D Human Trunk Neuromuscular Organoids

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Genome-wide aggregated trans-effects on risk of type 1 diabetes: A test of the “omnigenic” sparse effector hypothesis of complex trait genetics

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Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways

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Transcriptomic taxonomy and neurogenic trajectories of adult human,macaque, and pig hippocampal and entorhinal cells

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Landscape and Regulation of m6A and m6Am Methylome across Human and Mouse Tissues

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SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions

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