Biotech Reviews

Cover illustration: Biotech Reviews. The first BTJ Reviews-only issue is covering various exciting developments in biotechnology. Edited by Sophia Hober (Stockholm, Sweden) international researchers feature the state-of-the-art e.g. genomescale modeling, metagenomics, plant biotech. secondary metabolites or recombinant antibody production. Image from Artville/Getty Images.     

Next issue (March 2007): Textile biotechnology

Edited by Prof. Cavaco-Paolo (Lisbon, Portugal). Highlight articles: – Catalases for cleaner bleaching – Natural retting agents – Decolorization of reactive azo dyes – Wax removal for accelerated cotton scouring – Enzymatic cotton scouring products – Photochemical immobilization on polyethylene – Nitrilases for the surface modification of acrylic fibers – PET hydrolysis by Fusarium esterases – PVA-degrading enzymes in cotton fabric desizing ... and much more: Read the next issue of BTJ!     

Systems biology for industrial applications

Cover illustration: Systems biology for industrial applications. Biofuel production from lignocellulosic biomass is one of the key topics in industrial systems biology. This issue of BTJ edited by Jens Nielsen (Chalmers, Gothenburg, Sweden) covers reviews and original articles on systems biology approaches for biofuel production, i.e., metabolic flux analysis in Clostridia species as well as advancing metabolic engineering of yeasts, and sustainable chemistry in Corynebacterium glutamicum and microalgae. Image provided by Payam Ghiaci, Chalmers, Sweden.     

Biotech Reviews

Cover illustration: Biotech Reviews. This special issue, edited by Sophia Hober (Stockholm, Sweden) covers review articles on key areas of biotechnology, synthetic biology, metabolic engineering as well as protein and biofuel engineering, nanobiotechnology, siRNA therapeutics and food biotechnology. Cover image: SPDM/localization microscopy of nanostructures in human cell nuclei, H2A proteins (red) and Snf2H proteins (green) in a human osteosarcoma cell nucleus (U2OS cells), provided by Manuel Gunkel, Heidelberg, Germany, taken from the Review on superresolution imaging by Cremer et al. http://dx.doi.org/10.1002/biot.201100031 .     

Scaffold-free cell-based systems

Cover illustration Scaffold-free cell-based systems. This issue of BTJ, edited by Umut Gurkan (Harvard Medical School, MA, USA) and Feng Xu (Xi' an Jiaotong University, China) highlights several applications of scaffold-free systems such as cell therapies for tissue regeneration, in vitro functional tissue and disease models for drug sensitivity testing, cell-based biosensors, and drug delivery. Cover image: Confocal image of a microtissue generated from human colorectal carcinoma cell line, HCT-116, stained for integrin, 1 (green), cytoskeleton (red) and nuclei (blue). Image: Irina Agarkova (InSphero AG, Zurich, Switzerland). See the article by Drewitz et al., http://dx.doi.org/10.1002/biot.201100290     

Focus: Nutrigenomics

Cover illustration: Nutrigenomics aims to identify the genes that influence the risk of diet-related diseases on a genomewide scale, and to understand the mechanisms that underlie these genetic predispositions. This BTJ special issue edited by Taesun Park features articles uncovering ‘dietary signatures’ associated with obesity and metabolic diseases. Images copyright: Yellow, green, and red bell peppers. © Photodisc, Microarray; © http://genomics.energy.gov     

Next issue (May 2007): Brain-specific Diseases

Edited by Dr. Nektarios Tavernarakis, Heraklion, Greece Highlight articles: – Neuronal death vs neurogenesis after transient ischemia – C. elegans mitochondrial mutants to study human neurodegenerative diseases – Human huntingtin antibody epitope mapping – Amyotrophic lateral sclerosis – the tools of the trait – Biosensors for biogenic catecholamine detection – Comprehensive survey of p94/calpain 3 substrates by comparative proteomics – Molecular architecture of juxtaparanodal regions of myelinated fibers – Bio-electrosprays: A novel electrified jetting methodology for the safe handling and deployment of primary living organisms ... and much more: Read the next issue of BTJ!     

Upcoming articles in BTJ

Next issue: RNA-assisted Protein Folding The July 2008 issue of BTJ is devoted to RNA-assisted Protein Folding, edited by Professor Marc Blondel (Brest, France). BTJ will be featuring articles on: – Role of ribosomes in protein folding – Tools for the study of Ribosome-borne Protein Folding Activity (RPFA) – RNA-driven cyclin-dependent kinase regulation – The presence of rRNA sequences in polyadenylated RNAs and its potential functions – Non-coding RNAs in neurodegeneration and stress response – Folding at the rhythm of the rare codon beat Many of these exciting articles are already available online under “Early View”! A sneak preview of other content can be found under “News”. http://www.biotechnology-journal.com     

Biotech paper watch

BTJ best cover contest Biotech paper watch: Triple knockout cell lines in one go Turning carbon dioxide into liquid fuel Dual malaria/cholera vaccines from chloroplast Automated single cell clone picking Disulfide trapping of yeast surface proteins pH changes upon freezing of buffered solutions Identifying cancerspecific glycosylation p53, a double-edged sword in the fight against cancer Most read in BTJ: SUMOylation and cell signalling Bioengineering news: Biofuels for future generations Textile wastewater decolorization Engineering joint cartilage     

Biopharmaceutical Technologies

Cover image: Biopharmaceutical Technologies already represent 20% of the new pharmaceuticals and bioengineering is currently experiencing a revival. This special issue of BTJ, edited by Prof. Alois Jungbauer, features a wide variety of technical reports and research articles about protein expression, bioprocessing and molecular recognition. Image Pharmaceutical Production, ©Sandoz, Schaftenau, Austria (www.sandoz.at).     

Biotech in South Africa

Cover illustration: Biotech in South Africa. This BTJ special issue is edited by Professor Don Cowan (Cape Town, South Africa) and highlights many aspects on South African research and industry, ecology and economy. Images © Don Cowan (grasslands at the base of the Drakensberg Mountains, KwaZulu-Natal Province, SA), USGS (coal), USFDA (sugarcane) and Corbis Digital Stock (vines).     

Biotech in Korea

Cover illustration: Biotech in Korea. This special issue of BTJ is edited by our new co-Editor-in-Chief Sang Yup Lee from the Korea Advanced Institute of Science and Technology in Daejon. Featured are all aspects of bioeconomy, bioindustry and biotech research in Korea. Images: © http://mbel.kaist.ac.kr (background image), © 2001–2004 by IMGCLUB (Korean fan dance), © http://blog.naver.com/rapkyo4u (the eaves).     

Cover Picture: Biotechnology Journal 8/2016

This regular issue of BTJ includes articles on biocatalysis, biochemical engineering, and bioprocess engineering. This cover page highlights the applications of biomolecules (e.g., proteins, enzymes, and DNA) in ionic liquids (ILs). The technological utility of biomolecules can be enhanced significantly by combining them with ILs. Image is provided by Magaret Sivapragasam, Muhammad Moniruzzaman, and Masahiro Goto authors of ”Recent advances in exploiting ionic liquids for biomolecules: Solubility, stability and applications“ ( http://dx.doi.org/10.1002/biot.201500603 ).     

Cover Picture: Biotechnology Journal 10/2016

This regular issue of BTJ includes articles on analytical biotechnology, industrial biotechnology and metabolic engineering. The cover is inspired by the article "Chlorella species as hosts for genetic engineering and expression of heterologous proteins: Progress, challenge and perspective" by Bo Yang, Jin Liu, Yue Jiang and Feng Chen which is describing the heterologous proteins expressed in unicellular Chlorella species combined with the production of fine value‐added bioactives ( http://dx.doi.org/10.1002/biot.201500617 ).     

Biocatalysis

Cover illustration: In order to use rapeseed oil for e.g. biofuels, biocatalysts are needed for processing. Expanding the former limits of biocatalytic applications is the theme of this special issue of BTJ, edited by Dietmar Haltrich (Vienna, Austria) and Mikhail Rabinovich (Moscow, Russia). Highlights include protein engineering based on rational design or random mutagenesis, as well as enzyme adaptation for functioning in novel solvents including ionic liquids. Image of butterly on rapeseed field: courtesy of Jens Bredehorn (www.pixelio.de).     

Histochemical determination of the fiber composition of locomotory muscles in a lizard, Dipsosaurus dorsalis

A histochemical survey was done on the fiber composition of 12 different locomotory muscles in the lizard Dipsosaurus dorsalis. Three types of fibers were found in all muscles: (1) fast-twitch-glycolytic (FG); (2) fast-twitch-oxidative-glycolytic (FOG); and (3) tonic fibers. Virtually all locomotory muscles contain some tonic fibers. Most muscles have bulk white regions (containing mostly FG fibers) and distinct red, oxidative regions (with FOG and tonic fibers). These red regions are predominantly located around the joints in the hind limb muscles, and probably serve a postural and joint-stabilizing function. The predominance of FG fibers in the bulk white regions is well-correlated with the rapid, anaerobically supported predator escape behavior of D. dosalis.     

Cover Picture: Biotechnology Journal 5/2016

This regular issue of BTJ includes articles on biocatalysis, biomaterials, and industrial biotechnology. The cover picture shows several aspects of bacteriophage therapy, including phages adsorbing to bacterial cell surfaces, commercial preparations Pyo‐ and Intesi‐phages that are currently produced and used in Georgia, and administration of phages by medical staff to a patient. Image is provided by Aleksandre Ujmajuridze, Jon Caplin, Nino Chanishvili, and Aidan Coffey authors of ”Silk route to the acceptance and re‐implementation of bacteriophage therapy“ ( http://dx.doi.org/10.1002/biot.201600023 ).     

Biotech paper – market watch

Biotech paper watch: From our sister journals Other publications Most accessed in BTJ: Micro RNA BioEssays: Targeted gene repair by intrinsic cellular processes ES cell-derived biological pacemaker Zebrafish as a model for pancreas development and function New on the market: Wyatt Technology's protein analysis tool Agilent Technologies' HPLCchip for proteomics research     

Next issue (August 2007): Role of Kinases in Neuronal Function

Edited by Professor Marc Blondel, Brest, France Highlight articles: Role and regulation of Cdk5 in – neurofibrillary degeneration and neuronal death: the missing link to cell cycle reactivation – neuronal signaling, plasticity, and drug abuse – dendrite and synapse development – Cerebral ischemia, cell cycle elements ... and much more: Read the next issue of BTJ!