首页 | 本学科首页   官方微博 | 高级检索  
相似文献
 共查询到20条相似文献,搜索用时 46 毫秒
1.
Changes in visual evoked potentials were studied in rats at different stages of formation of experimental photogenic epilepsy induced by injection of tetanus toxin into the lateral geniculate body. The greatest change in evoked potentials in the lateral geniculate body consisted of the appearance of an aditional component in the series of waves of the primary response. Meanwhile in the ipsilateral visual cortex the amplitude of the first negative component of the evoked potential was considerably increased. Correlation was found between the changes in the amplitude of this component in the visual cortex and the change in steepness of the additional component of the evoked potential in the geniculate body, reflecting functional reorganization of that nucleus. The results are evidence of significant disturbances of the relay function of the lateral geniculate body when a generator of pathologically enhanced excitation is formed in it.Institute of General Pathology and Pathological Physiology, Academy of Medical Sciences of the USSR, Moscow. Translated from Neirofiziologiya, Vol. 10, No. 2, pp. 142–149, March–April, 1978.  相似文献   

2.
Experiments on cats showed that complete operative exclusion of the reticular formation by precollicular section prevents the development of habituation of evoked potentials in the primary visual projection area and lateral geniculate body. Similar results were obtained after postcollicular section of the mesencephalon. The phenomenon of habituation of visual evoked potentials is found in posttrigeminal preparations. It is postulated that the tonic inhibitory division of the reticular formation plays an important role in the development of the habituation phenomenon.Odessa State Medical Institute. Translated from Neirofiziologiya, Vol. 4, No. 5, pp. 540–544, September–October, 1972.  相似文献   

3.
Recovery curves of evoked potentials in the association and visual cortex during paired stimulation of the pulvinar in chronic experiments on alert cats were shown to be similar in character. Depression of the test response was observed only if the interval between stimuli was of the order of 10 msec, but if it was 40 msec considerable (2–4 times) facilitation of the second response was observed, mainly on account of an increase in the negative component N1. Facilitation was less marked if the intervals were from 60 to 100 msec, and they decreased gradually to an interval of 200 msec. The recovery curve of cortical evoked potentials during paired stimulation of the lateral geniculate body differed considerably from the recovery curve during paired stimulation of the pulvinar and was characterized by a gradual increase in amplitude of the second response — from its almost total suppression with an interval of 10 msec to slight facilitation with an interval of 200 msec. If intervals of 10 to 80 msec were used, the test response was restored more slowly in the association cortex than in the visual cortex. The results are discussed from the standpoint of differences in the character of intracortical spread of excitation as a result of activation of geniculo-cortical and pulvinar-cortical pathways of conduction of information.Institute of Higher Nervous Activity and Neurophysiology, Academy of Sciences of the USSR, Moscow. Translated from Neirofiziologiya, Vol. 16, No. 4, pp. 497–505, July–August, 1984.  相似文献   

4.
Eye movements evoked by local electrical stimulation of the dorsal nucleus of the lateral geniculate body were analyzed after removal of the visual cortex and in intact animals during trials on awake cats. No significant difference was observed between the eye movement patterns of the two animal groups evoked by electrical stimulation. These movements could be classed into three main groups: those unassociated with the starting position of the eyes in orbit (or unidirectional movements), goal-directed, and centered movements, with direction depending on the initial position of the eyes in their orbits. Our findings indicate that the cortical visual areas are neither the principal nor an indispensable link in the chain for transmitting signals evoked by (electrically) stimulating the geniculate body from the cortical structures of the direct visual pathway towards the operative links of the oculomotor system. Potential pathways for conducting information from the dorsal nucleus of the lateral geniculate body to oculomotor system structures are discussed.I. P. Pavlov Institute of Physiology, Academy of Sciences of the USSR, Leningrad. Translated from Neirofiziologiya, Vol. 19, No. 2, pp. 164–170, March–April, 1987.  相似文献   

5.
The effect of amygdaloid stimulation on retrieval of delayed evoked potentials recorded in the cortex, mesencephalic reticular formation, lateral geniculate body, and hippocampus was investigated in unanesthetized curarized cats. Delayed evoked potentials were produced to 10–400 combinations of flashes and hypothalamic stimulation and consisted of potentials arising in response to a conditioned stimulus after a delay equal to the interval between it and the unconditioned stimulus. Amygdaloid stimulation facilitated the retrieval of these potentials if they had first been extinguished or had not appeared during initial testing.Institute of Physiology, Academy of Medical Sciences of the USSR, Siberian Branch, Novosibirsk. Translated from Neirofiziologiya, Vol. 8, No. 3, pp. 300–304, May–June, 1976.  相似文献   

6.
Efferent connections of medial (nucleus cuneiformis) and lateral regions of the midbrain reticular formation (MRF) were investigated using an anterograde autoradiographic technique in cats. Efferent fibers from the MRF ascend to the globus pallidus, substantia innominata, hypothalamus, subthalamus, and nonspecific associative and relay nuclei of the thalamus. Descending pathways to the conclusion that the cuneiform nucleus is more of a nonspecific structure than an association auditory center. The lateral reticular region had numerous projections to the lateral geniculate body and, together with the parabigeminal nucleus, forms the midbrain visual complex.I. P. Pavlov Institute of Physiology, Academy of Sciences of the USSR, Leningrad. Translated from Neirofiziologiya, Vol. 17, No. 5, pp. 646–652, September–October, 1985.  相似文献   

7.
In response to stimulation of the posterior lateral nucleus in unanesthetized cats immobilized with D-tubocurarine an evoked potential consisting of three components with a latent period of 3–5 msec appeared in area 5b of the suprasylvian gyrus. All three components were reversed at about the same depth in the cortex (1500–1600 µ). Reversal of the potential shows that it is generated in that area by neurons evidently located in deeper layers of the cortex and is not conducted to it physically from other regions. Responses of 53 spontaneously active neurons in the same area of the cortex to stimulation of the posterior lateral nucleus were investigated. A characteristic feature of these reponses was that inhibition occurred nearly all of them. In 22 neurons the responses began with inhibition, which lasted from 30 to 400 msec. In 30 neurons inhibition appeared immediately after excitation while one neuron responded by excitation alone. The latent periods of the excitatory responses varied from 3 to 28 msec. The short latent period of the evoked potentials and of some single units responses (3–6 msec) confirms morphological evidence of direct connections between the posterior lateral nucleus and area 5b of the suprasylvian gyrus. Repetitive stimulation of that nucleus led to strengthening of both excitation and inhibition. Influences of the posterior lateral nucleus were opposite to those of the specific nuclei: the posterior ventrolateral nucleus and the lateral and medial geniculate bodies. Stimulation of the nonspecific reticular nucleus, however, evoked discharges from neurons like those produced by stimulation of the posterior lateral nucleus.A. A. Bogomolets Institute of Physiology, Academy of Sciences of the Ukrainian SSR, Kiev. Translated from Neirofiziologiya, Vol. 5, No. 5, pp. 502–509, September–October, 1973.  相似文献   

8.
Systematic research was conducted into the parafascicular complex of the nonspecific nociceptive system of the rabbit hypothalamus using a technique of evoked potentials. Two types of evoked response were recorded during electrocutaneous stimulation of the paw; a compound response consisting of early and late positive-negative potentials in the lateral region and a simple positive-negative evoked potential in the medial area. Evidence suggests a more complex organization of the thalamic parafascicular complex in leporines than previously supposed.I. P. Pavlov Institute of Physiology, Academy of Sciences of the USSR, Leningrad. Translated from Neirofiziologiya, Vol. 18, No. 6, pp. 787–793, November–December, 1986.  相似文献   

9.
In acute experiments on anesthetized cats it was shown that a single stimulation of the ocular muscles leads to unambiguous changes in the formation of the negative and positive components of the evoked response of the lateral geniculate nucleus to the presentation of a light stimulus. It was established that the nature of the muscular influences on the formation of these components of the evoked response of the lateral geniculate nucleus depends on the interval between conditioning muscular and test light stimuli.A. I. Karaev Institute of Physiology, Academy of Sciences of the Azerbaidzhan Republic, Baku. Translated from Neirofiziologiya, Vol. 23, No. 4, pp. 451–455, July–August, 1991.  相似文献   

10.
Data on the evolution of the visual system in vertebrate phylogeny are described. Visual projections are demonstrated in the telencephalon of cyclostomata (lampreys). The existence of a retino-thalamo-telencephalic pathway is demonstrated in elasmobranchs (skates). Two visual pathways are present in amphibians (frogs) and reptiles (turtles): retino-thalamo-telencephalic and retino-tecto-thalamo-telencephalic, and these overlap partly at the thalamic level in the lateral geniculate nucleus and completely in the telencephalon. In turtles the earliest visual and tectal impulses relay on their way to the telencephalon in the lateral geniculate body, and later impulses relay in the nucleus rotundus. In mammals (rats) visual tecto-cortical connections are seen; judging from the latent period of potentials arising in the visual cortex in response to stimulation of the superior colliculi these connections have one synaptic relay in the thalamus. The much shorter latent periods of visual evoked potentials recorded in the tectum of the monkey than in turtles (under identical chronic experimental conditions) confirm the views of morphologists on the progressive development of the tectal division of the visual system in vertebrate phylogeny. It is concluded that corticalization of both divisions of the visual system, i.e., the existence of telencephalic representation, appears in the early stages of vertebrate evolution.  相似文献   

11.
Unit responses in area 17 of the visual cortex to stimulation of the lateral geniculate body and optic tract were studied in experiments on unanesthetized cats immobilized with D-tubocurarine. Of the neurons tested, 53.6% responded to stimulation of the lateral geniculate body. In 92% of these cells the responses were orthodromic with latent periods of between 2 and 12.5 msec. Most cells responded with latent periods of 2.0–2.5, 3.0–3.5, and 4.0–4.5 msec, corresponding to latent periods of the components of the electropositive wave of the primary response. Antidromic responses to stimulation of the lateral geniculate body were given by 8% of neurons. The difference between the latent periods of responses of the same visual cortical neurons to stimulation of the optic tract and lateral geniculate body was 0.1–1.8 msec, but for most neurons (55.8%) it was 0.5–1 msec. The histograms of response latencies of visual cortical neurons to stimulation of the above-mentioned formations were found to be similar. It is concluded that the optic radiation contains three principal groups of fibers with conduction velocities of 28.5–16.6, 11.7–8.9, and 7.4–6.0 m/sec, respectively.A. A. Bogomolets Institute of Physiology, Academy of Sciences of the Ukrainian SSR, Kiev. Translated from Neirofiziologiya, Vol. 7, No. 6, pp. 589–596, November–December, 1975.  相似文献   

12.
Electrophysiological experiments were made on conscious cats with different degree of dissection of the classical and commissural optic tracts to the lateral geniculate body. The data obtained indicated that dissection of the direct retinal tracts to the lateral geniculate body (unilateral dissection of the optic tract) leads merely to the reduction in the amplitude of evoked potentials in response to light flashes. However, the latent period of the first component of the response in this structure appeared the same as in intact animals. Comparison of these data with those obtained in analogous experiments made on the visual cortex allows the conclusion that the geniculate body is the main subcortical relay of the visual commissural effects which are transmitted from the retina to the cortical regions of the brain.  相似文献   

13.
In experiments on immobilized, lightly anesthetized turtles the presence of visual and somatic representation was established in the subcortical striatal division of the forebrain — the pallial thickening, the dorsal ventricular ridge, and the putamen. In their physiological characteristics they are similar to the corresponding representation in the general cortex. The absence of significant differences between the latent periods of cortical and striatal evoked potentials to flashes and to stimulation of the dorsal thalamus indicates that visual projection fibers (from the lateral geniculate body) terminate at both cortical and striatal levels. Differences in the distribution of latent periods of unit responses in the cortex to visual and thalamic stimulation are due to the presence of a rotundo-telencephalic visual channel, with direct connections with the striatal and polysynaptic connections with the general cortex, as well as the geniculo-telencephalic tract. Considerable differences between the latent periods of the evoked potentials and also between unit responses to electrodermal stimulation in the cortical and striatal structures indicate that somatic projection fibers relay in the striatum on their path to the general cortex. Consequently, the somatosensory system of turtles is less corticalized than the visual system. Comparison of the results described with those obtained by workers studying other vertebrates suggests that the afferent supply of the striatum may be reorganized in the transition from premammals to mammals.I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Academy of Sciences of the USSR, Leningrad. Translated from Neirofiziologiya, Vol. 7, No. 2, pp. 184–193, March–April, 1973.  相似文献   

14.
The dynamics of structural and functional characteristics of residual neurons in the degenerating lateral geniculate body was studied in cats during the 4–12 months after division of all cortico-subcortical projection connections, including axons of relay cells of the lateral geniculate body [9]. Spontaneous and evoked activity of the residual cells, their number, and also the dimensions of the cell bodies were investigated. With lengthening of the postoperative period a decrease in the number of cells of the lateral geniculate body responding to photic stimulation and also destruction of their receptive fields were observed; 12 months after the operation the residual neurons of the lateral geniculate body lose their sensitivity to photic stimulation. Morphological investigation revealed a progressive reduction in the number of neurons in the degenerating lateral geniculate body and predominance of small neurons among them. The nature of interneuronal relations in the lateral geniculate body are discussed on the basis of the results.Research Institute of Experimental Medicine, Academy of Medical Sciences of the USSR, Leningrad. Translated from Neirofiziologiya, Vol. 9, No. 6, pp. 575–582, November–December, 1977.  相似文献   

15.
In acute experiments on cats we investigated evoked potentials from the cingulate gyrus developed in response to stimulation of somatic and visceral nerves; also potentials from various parts of the hypothalamus, and midbrain reticular formation. We showed that the nonspecific afferent system influences electrical activity in the limbic cortex through hypothalamic pathways. We consider the limbic cortex to be part of the association area of the neocortex and that the associative responses of the cortex are more complex in nature than is usually thought to be the case, and that they are formed under the influence of impulses arriving at the cortex along many specific and nonspecific pathways. The hypothalamo—cingulate system is one of the main systems of cortico—subcortical integration. It plays an important part in regulation of autonomic, somatic, and emotional responses.L. A. Orbeli Institute of Physiology, Academy of Sciences of the Armenian SSR, Erevan. Translated from Neirofiziologiya, Vol. 2, No. 5, pp. 451–459, September–October, 1970.  相似文献   

16.
Recovery cycles of mass evoked potentials of the optic tract, lateral geniculate body, optic radiation, and primary projection area of the visual cortex were investigated in amytal-anesthetized cats following electrical stimulation of the optic nerve (in some experiments, optic radiation) by paired short stimuli of supraliminal intensity. The recovery of the amplitude and time characteristics of all components of the mass responses to a testing stimulus applied to the nerve at different intervals after an identical conditioning stimulus was studied. The responses of all portions of the visual system (except the retina) were recorded simultaneously, which made it possible to compare the changes of their reactivity arising after the first stimulus under rigorously identical conditions. It was shown that at the upper levels of the visual system the exaltation phase of the recovery cycle and the depression phase following it become increasingly more pronounced and protracted. Depression is especially pronounced in the visual cortex, which maximally affects the recovery of the late components of the mass response. Under the experimental conditions the processes of successive inhibition in the cortex were more pronounced than at the lower levels. There are grounds to assume that the depression of the cortical responses is partially due to pre- and partially postsynaptic inhibition.Institute of Higher Nervous Activity and Neurophysiology, Academy of Sciences of the USSR, Moscow. Translated from Neirofiziologiya, Vol. 2, No. 3, pp. 251–259, May–June, 1970.  相似文献   

17.
The thalamic relays for the conduction of impulses arising during photic stimulation of the eyes and electrical stimulation of the tectum in the general cortex, hyperstriatum (the dorsal ventricular ridge), and the striatum proper were studied in the turtleEmys orbicularis. Acute experiments on immobilized animals showed that anodal polarization temporarily and destruction of n. rotundus irreversibly suppress the main negative wave of the responses to tectal stimulation and to flashes in the hyperstriatum, whereas the corresponding responses in the general cortex still persist. Polarization and destruction of the lateral thalamic region, including the lateral geniculate body, have the opposite effect: responses in the hyperstriatum to photic and tectal stimulation are virtually unchanged whereas those in the general cortex disappear, except their late components. Preceding single stimulation of the tectum or n. rotundus depresses responses in the hyperstriatum evoked by flashes. However, during stimulation of the lateral thalamic region, combined potentials and single unit responses appear in the hyperstriatum and interact with responses evoked by tectal stimulation. It is concluded that the main pathways in turtles which supply visual information to the general cortex and hyperstriatum differ: the former relay in the lateral thalamic region, the latter in n. rotundus, although some overlapping of their projections in the hyperstriatum and striatum is possible.I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Leningrad. Translated from Neirofiziologiya, Vol. 9, No. 5, pp. 486–494, September–October, 1977.  相似文献   

18.
Acute experiments on cats anesthetized with pentobarbital and immobilized with diplacin or listhenon showed that visceral and somatic excitation may either facilitate or inhibit single unit activity in the lateral geniculate body evoked by photic stimulation. The manifestations of facilitation were: a modulatory type of enhancement of responses of silent neurons and neurons with a low level of spontaneous activity; enhancement of responses accompanied by simultaneous depression of spontaneous activity — a sensory contrast effect; enhancement of long-latency responses; appearance of a short-latency discharge from cells with an inhibitory response to light; the appearance of responses to light in neurons not responding previously or stabilization of responses in neurons responding to light irregularly. The inhibitory effects were manifested as immediate inhibition of responses, usually long-latency, and the filling up of the inhibitory pauses of the response to light with spikes, leading to a decrease in the signal-noise ratio. Somatic stimulation was more effective and more frequently evoked facilitation of responses to light (in 74% of cells). Similar results were obtained by stimulation of the mesencephalic reticular formation. Visceral excitation gave rise to facilitatory and inhibitory effects to an almost equal degree. The results show that excitation arising as the result of visceral and somatic stimulation affects the conduction of visual information in the neuronal system of the lateral geniculate body.Ivano-Frankovsk Medical Institute. Institute of Experimental Medicine, Academy of Medical Sciences of the USSR, Leningrad. Translated from Neirofiziologiya, Vol. 5, No. 6, pp. 636–643, November–December, 1973.  相似文献   

19.
Evoked potentials arising in the motor cortex in response to its direct stimulation (dendritic and slow negative potentials), to stimulation of the ventrolateral (primary response) and intralaminar (nonspecific response) thalamic nuclei, and to stimulation of the pyramidal tracts (antidromic response), and also postsynaptic responses of neurons corresponding to them were studied in acute experiments on curarized cats. Evoked potentials arising in response to direct cortical stimulation and also to stimulation of the specific and nonspecific thalamic nuclei and pyramidal tracts were recorded from the same point of the motor cortex, and the corresponding intracellular responses were recorded from the same neuron. Slow negative potentials arising under these conditions of stimulation and the IPSPs corresponding to them were shown to have an identical time course. The results show that slow negative potentials are a reflection of hyperpolarization of pyramidal neurons. It is suggested that the individual components of responses evoked by direct stimulation of the cortex and thalamic nuclei have a common genesis.I. S. Beritashvili Institute of Physiology, Academy of Sciences of the Georgian SSR, Tbilisi. Translated from Neirofiziologiya, Vol. 14, No. 2, pp. 115–121, March–April, 1982.  相似文献   

20.
Elimination of reticular inputs to the lateral geniculate body (LGB) by sectioning of one half of the midbrain operculum, did not affect significantly the characteristics of the LGB evoked potential to light stimulus. At the same time LGB response to stimulation of the reticular formation by a single current impulse, though did not disappear completely, but changed greatly: its latency became twice as long, the negative component of the response was no more recorded. In conditions of LGB deafferentation, the characteristics of all rhythms of its electrical activity, besides the alpha-like one, considerably changed. At the same time, exactly this last rhythm underwent the greatest changes on the EEG of the visual cortex. On the basis of the obtained data it is suggested that the reticular formation takes a considerable and multiple part in generation of LGB rhythmic activity and that changes in its characteristics are clearly reflected in the ECoG rhythms formation. Retention of the LGB visual evoked potential and of the response to stimulation of the reticular formation after the section of one half of the midbrain operculum testifies to the presence of several reticular inputs to LGB.  相似文献   

设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号