Ancient Cuzco: Heartland of the Inca

Ancient Cuzco: Heartland of the Inca . Brian S. Bauer. Austin: University of Texas Press, 2004. 255 pp.     

Inca expansion and parasitism in the lluta valley: preliminary data

Assessing the impact of cultural change on parasitism has been a central goal in archaeoparasitology. The influence of civilization and the development of empires on parasitism has not been evaluated. Presented here is a preliminary analysis of the change in human parasitism associated with the Inca conquest of the Lluta Valley in Northern Chile. Changes in parasite prevalence are described. It can be seen that the change in life imposed on the inhabitants of the Lluta Valley by the Incas caused an increase in parasitism.     

Plant motifs on Inca ceremonial vases from Peru*

Fourteen Families, 21 genera and 23 species have been described in this work, as motifs identified on the ancient wooden carved and painted vases known as keros. These date from the early colonial or transitional epoch between the pre-conquest Inca styles and those coming later with very strong Spanish influence. Although many of the well-known food, medicinal, ornamental and ritual plants are depicted, a large number of plants known to the Incas, both wild and cultivated, is absent. Certain motifs have been impossible to identify, but it is hoped that future studies may throw considerable light on the decorative and symbolic motifs in this interesting group of vases.     

Maintenance of Leukemia-Initiating Cells Is Regulated by the CDK Inhibitor Inca1

Functional differences between healthy progenitor and cancer initiating cells may provide unique opportunities for targeted therapy approaches. Hematopoietic stem cells are tightly controlled by a network of CDK inhibitors that govern proliferation and prevent stem cell exhaustion. Loss of Inca1 led to an increased number of short-term hematopoietic stem cells in older mice, but Inca1 seems largely dispensable for normal hematopoiesis. On the other hand, Inca1-deficiency enhanced cell cycling upon cytotoxic stress and accelerated bone marrow exhaustion. Moreover, AML1-ETO9a-induced proliferation was not sustained in Inca1-deficient cells in vivo. As a consequence, leukemia induction and leukemia maintenance were severely impaired in Inca1^−/− bone marrow cells. The re-initiation of leukemia was also significantly inhibited in absence of Inca1^−/− in MLL—AF9- and c-myc/BCL2-positive leukemia mouse models. These findings indicate distinct functional properties of Inca1 in normal hematopoietic cells compared to leukemia initiating cells. Such functional differences might be used to design specific therapy approaches in leukemia.     

Processes of State Formation in the Inca Heartland (Cuzco, Peru)

This article addresses Inca state formation in the central highlands of Peru. Using ethnohistoric materials and new archaeological survey data from three areas surrounding Cuzco, the capital of the Inca empire, we argue that rapid Inca expansion after C.E. 1400 was made possible by long-term processes of state formation and regional consolidation. From C.E. 1000-1400, a centralized state developed in the Cuzco Valley, extending its direct administrative control over numerous neighboring groups. Less powerful neighboring polities accepted Inca adm nistration early on, perhaps even n tiating Inca patronage. Strong rivals to Inca control maintained their independence, at times depopulating intermediate areas and settling in defensive sites to protect settlements and resources. Finally, groups of intermediate complexity used alliances and violence to align themselves with the strongest regional competitors. Such variability in regional integration strategies reveals how Inca state formation processes influenced later patterns of imperial conquest and administraton. [Keywords: inca, state formation, imperialism, archaeology, ethnicityl     

Bio-Inspired Wooden Actuators for Large Scale Applications

Implementing programmable actuation into materials and structures is a major topic in the field of smart materials. In particular the bilayer principle has been employed to develop actuators that respond to various kinds of stimuli. A multitude of small scale applications down to micrometer size have been developed, but up-scaling remains challenging due to either limitations in mechanical stiffness of the material or in the manufacturing processes. Here, we demonstrate the actuation of wooden bilayers in response to changes in relative humidity, making use of the high material stiffness and a good machinability to reach large scale actuation and application. Amplitude and response time of the actuation were measured and can be predicted and controlled by adapting the geometry and the constitution of the bilayers. Field tests in full weathering conditions revealed long-term stability of the actuation. The potential of the concept is shown by a first demonstrator. With the sensor and actuator intrinsically incorporated in the wooden bilayers, the daily change in relative humidity is exploited for an autonomous and solar powered movement of a tracker for solar modules.