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Leppik L Gunst K Lehtinen M Dillner J Streker K de Villiers EM 《Journal of virology》2007,81(17):9346-9356
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We examined the enzyme activities associated with progeny subviral particles isolated from L-cells infected with reovirus at 12 h postinfection. Activities normally present in reovirus cores were also found to be present in the progeny subviral particles, with the exception of the capping enzymes. The methylase and guanyl transferase activities, which constitute the capping system, were present in a masked form that could be activated by chymotrypsin digestion. The appearance of these progeny subviral particles in infected cells coincided with the time when mRNA synthesis was maximal, suggesting that viral mRNA synthesized at later times is uncapped. 相似文献
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Novel transcription map for the B19 (human) pathogenic parvovirus 总被引:30,自引:15,他引:15
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